产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
水闸蛋白1多克隆抗体(MH25)
目录 :
71-7800
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
MH25
反应物种 :
人类, 小鼠, 大鼠, , domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 75
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:500; 图 6d
Xing T, Benderman L, Sabu S, Parker J, Yang J, Lu Q, et al. Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation. Cell Mol Gastroenterol Hepatol. 2020;9:641-659 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3a
Rogerson C, Gissen P. VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1609-1621 pubmed 出版商
  • 免疫印迹; 大鼠; 1:250; 图 7c
Beaumont M, Andriamihaja M, Armand L, Grauso M, Jaffrézic F, Laloë D, et al. Epithelial response to a high-protein diet in rat colon. BMC Genomics. 2017;18:116 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Wu C, Feng X, Lu M, Morimura S, Udey M. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis. J Clin Invest. 2017;127:623-634 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 1b
Fall B, Scott C, Mauer M, Shankland S, Pippin J, Jefferson J, et al. Urinary Podocyte Loss Is Increased in Patients with Fabry Disease and Correlates with Clinical Severity of Fabry Nephropathy. PLoS ONE. 2016;11:e0168346 pubmed 出版商
  • 免疫组化; 小鼠; 图 3e
Yuan J, Cha J, Deng W, Bartos A, Sun X, Ho H, et al. Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation. Proc Natl Acad Sci U S A. 2016;113:E8079-E8088 pubmed
  • 免疫印迹; 人类; 1:1000; 图 2a
Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed 出版商
  • 免疫细胞化学; domestic rabbit; 1:100; 图 6a
  • 免疫印迹; domestic rabbit; 1:1000; 图 6b
Martínez Rendón J, Sánchez Guzmán E, Rueda A, González J, Gulias Cañizo R, Aquino Jarquin G, et al. TRPV4 Regulates Tight Junctions and Affects Differentiation in a Cell Culture Model of the Corneal Epithelium. J Cell Physiol. 2017;232:1794-1807 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5a
Keppner A, Malsure S, Nobile A, Auberson M, Bonny O, Hummler E. Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis. Inflamm Bowel Dis. 2016;22:2824-2839 pubmed
  • 免疫印迹; 人类; 图 1a
  • 免疫细胞化学; 犬; 图 7a
  • 免疫印迹; 犬; 图 1b
Fujii N, Matsuo Y, Matsunaga T, Endo S, Sakai H, Yamaguchi M, et al. Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells. J Biol Chem. 2016;291:24787-24799 pubmed
  • 免疫印迹; 小鼠; 1:250; 图 7a
Lan A, Blais A, Coelho D, Capron J, Maarouf M, Benamouzig R, et al. Dual effects of a high-protein diet on DSS-treated mice during colitis resolution phase. Am J Physiol Gastrointest Liver Physiol. 2016;311:G624-G633 pubmed 出版商
  • 免疫组化; 小鼠; 图 3c
Porat Shliom N, Tietgens A, Van Itallie C, Vitale Cross L, Jarnik M, Harding O, et al. Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo. Hepatology. 2016;64:1317-29 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Teo W, Merino V, Cho S, Korangath P, Liang X, Wu R, et al. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. 2016;35:5539-5551 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3
Strazielle N, Creidy R, Malcus C, Boucraut J, Ghersi Egea J. T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium. PLoS ONE. 2016;11:e0150945 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s2
Achamrah N, Nobis S, Breton J, Jésus P, Belmonte L, Maurer B, et al. Maintaining physical activity during refeeding improves body composition, intestinal hyperpermeability and behavior in anorectic mice. Sci Rep. 2016;6:21887 pubmed 出版商
Zhou Y, Zhang Z, Sun Y, Zhou D, Zhao Y, Li J, et al. Liangxue Tongyu Prescription Alleviates Brain Damage in Acute Intracerebral Hemorrhage Rats by Regulating Intestinal Mucosal Barrier Function. Evid Based Complement Alternat Med. 2022;2022:2197763 pubmed 出版商
Park N, Cha J, Sung P, Jang J, Choi J, Yoon S, et al. MiR-23b-3p suppresses epithelial-mesenchymal transition, migration, and invasion of hepatocellular carcinoma cells by targeting c-MET. Heliyon. 2022;8:e11135 pubmed 出版商
Singh V, Almpani M, Maura D, Kitao T, Ferrari L, Fontana S, et al. Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy. Nat Commun. 2022;13:5103 pubmed 出版商
Hinman S, Massaro A, Wang Y, Sims C, Kim R, Allbritton N. Suspended Collagen Hydrogels to Replicate Human Colonic Epithelial Cell Interactions with Immune Cells. Adv Biol (Weinh). 2022;6:e2200129 pubmed 出版商
Zinserling V, Semenova N, Bikmurzina A, Kruglova N, Rybalchenko O, Markov A. SARS-CoV-2-Induced Pathology-Relevance to COVID-19 Pathophysiology. Pathophysiology. 2022;29:281-297 pubmed 出版商
Zhao X, Zheng S, Wei S, Tian Q, Tao Y, Bo R, et al. The protective effect and potential mechanisms of eugenol against Salmonella in vivo and in vitro. Poult Sci. 2022;101:101801 pubmed 出版商
Klingler S, Hsu K, Hua G, Martin M, Adileh M, Baslan T, et al. Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells. JCI Insight. 2022;7: pubmed 出版商
Chiu K, Bashir S, Abdel Hamid A, Clark L, Laws M, Cann I, et al. Isolation of DiNP-Degrading Microbes from the Mouse Colon and the Influence DiNP Exposure Has on the Microbiota, Intestinal Integrity, and Immune Status of the Colon. Toxics. 2022;10: pubmed 出版商
Wilson S, Howden S, Vanslambrouck J, Dorison A, Alquicira Hernández J, Powell J, et al. DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets. Genome Med. 2022;14:19 pubmed 出版商
Habibi M, Shili C, Sutton J, Goodarzi P, Pezeshki A. Dietary branched-chain amino acids modulate the dynamics of calcium absorption and reabsorption in protein-restricted pigs. J Anim Sci Biotechnol. 2022;13:15 pubmed 出版商
Mircea M, Hochane M, Fan X, Chuva de Sousa Lopes S, Garlaschelli D, Semrau S. Phiclust: a clusterability measure for single-cell transcriptomics reveals phenotypic subpopulations. Genome Biol. 2022;23:18 pubmed 出版商
Boonhai S, Bootdee K, Saisorn W, Takkavatakarn K, Sitticharoenchai P, Tungsanga S, et al. TMAO reductase, a biomarker for gut permeability defect induced inflammation, in mouse model of chronic kidney disease and dextran sulfate solution-induced mucositis. Asian Pac J Allergy Immunol. 2021;: pubmed 出版商
Crakes K, Pires J, Quach N, Ellis Reis R, Greathouse R, Chittum K, et al. Fenofibrate promotes PPARα-targeted recovery of the intestinal epithelial barrier at the host-microbe interface in dogs with diabetes mellitus. Sci Rep. 2021;11:13454 pubmed 出版商
Hasegawa T, Mizugaki A, Inoue Y, Kato H, Murakami H. Cystine reduces tight junction permeability and intestinal inflammation induced by oxidative stress in Caco-2 cells. Amino Acids. 2021;53:1021-1032 pubmed 出版商
Scalisi J, Balau B, Deneyer L, Bouchat J, Gilloteaux J, Nicaise C. Blood-brain barrier permeability towards small and large tracers in a mouse model of osmotic demyelination syndrome. Neurosci Lett. 2021;746:135665 pubmed 出版商
Zhao X, Zhou J, Liang W, Sheng Q, Lu L, Chen T, et al. Probiotics mixture reinforces barrier function to ameliorate necrotizing enterocolitis by regulating PXR-JNK pathway. Cell Biosci. 2021;11:20 pubmed 出版商
El Chami C, Foster A, Johnson C, Clausen R, Cornwell P, Haslam I, et al. Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes. Br J Dermatol. 2021;184:482-494 pubmed 出版商
Rui Zhi T, Hui D, Jian Chun L, Xia Z, Xiao Jia W, Dan W, et al. Astragalus mongholicus Bunge and Panax Notoginseng Formula (A&P) Combined With Bifidobacterium Contribute a Renoprotective Effect in Chronic Kidney Disease Through Inhibiting Macrophage Inflammatory Response in Kidney and Intestine. Front Physiol. 2020;11:583668 pubmed 出版商
Ling J, Sckaff M, Tiwari M, Chen Y, Li J, Jones J, et al. RAS-mediated suppression of PAR3 and its effects on SCC initiation and tissue architecture occur independently of hyperplasia. J Cell Sci. 2020;133: pubmed 出版商
Kimura S, Tsuchiya A, Ogawa M, Ono M, Suda N, Sekimoto K, et al. Tissue-scale tensional homeostasis in skin regulates structure and physiological function. Commun Biol. 2020;3:637 pubmed 出版商
Yamashita K, Mizuno K, Furukawa K, Hirose H, Sakurai N, Masuda Hirata M, et al. Phosphorylation and dephosphorylation of Ser852 and Ser889 control the clustering, localization and function of PAR3. J Cell Sci. 2020;133: pubmed 出版商
GAO P, Guo K, Pu Q, Wang Z, Lin P, Qin S, et al. oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa. Front Immunol. 2020;11:1696 pubmed 出版商
Shi Y, Cui X, Sun Y, Zhao Q, Liu T. Intestinal vitamin D receptor signaling ameliorates dextran sulfate sodium-induced colitis by suppressing necroptosis of intestinal epithelial cells. FASEB J. 2020;34:13494-13506 pubmed 出版商
Alberto Silva C, Franzin C, Gilio J, Bonfim R, Querobino S. Toxicological effects of bioactive peptide fractions obtained from Bothrops jararaca snake venom on the structure and function of mouse seminiferous epithelium. J Venom Anim Toxins Incl Trop Dis. 2020;26:e20200007 pubmed 出版商
Shin M, Yong C, Oh S. Regulatory Effect of Lactobacillus brevis Bmb6 on Gut Barrier Functions in Experimental Colitis. Foods. 2020;9: pubmed 出版商
Yu S, Li Y, Zhao H, Wang Q, Chen P. The Histone Demethylase JMJD1C Regulates CAMKK2-AMPK Signaling to Participate in Cardiac Hypertrophy. Front Physiol. 2020;11:539 pubmed 出版商
Shi Y, Liu Z, Cui X, Zhao Q, Liu T. Intestinal vitamin D receptor knockout protects from oxazolone-induced colitis. Cell Death Dis. 2020;11:461 pubmed 出版商
Wu C, Lu M, Feng X, Nakato G, Udey M. Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins. Cells. 2020;9: pubmed 出版商
Molloy K, Cagney G, Dillon E, Wynne K, Greene C, McElvaney N. Impaired Airway Epithelial Barrier Integrity in Response to Stenotrophomonas maltophilia Proteases, Novel Insights Using Cystic Fibrosis Bronchial Epithelial Cell Secretomics. Front Immunol. 2020;11:198 pubmed 出版商
Koumangoye R, Omer S, Kabeer M, Delpire E. Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation. Cell Mol Gastroenterol Hepatol. 2020;9:239-255 pubmed 出版商
Tulyeu J, Kumagai H, Jimbo E, Watanabe S, Yokoyama K, Cui L, et al. Probiotics Prevents Sensitization to Oral Antigen and Subsequent Increases in Intestinal Tight Junction Permeability in Juvenile-Young Adult Rats. Microorganisms. 2019;7: pubmed 出版商
Al Kindi A, Alkahtani A, Nalubega M, El Chami C, O Neill C, Arkwright P, et al. Staphylococcus aureus Internalized by Skin Keratinocytes Evade Antibiotic Killing. Front Microbiol. 2019;10:2242 pubmed 出版商
Cremonini E, Daveri E, Mastaloudis A, Adamo A, Mills D, Kalanetra K, et al. Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis. Redox Biol. 2019;26:101269 pubmed 出版商
Marunaka K, Fujii N, Kimura T, Furuta T, Hasegawa H, Matsunaga T, et al. Rescue of tight junctional localization of a claudin-16 mutant D97S by antimalarial medicine primaquine in Madin-Darby canine kidney cells. Sci Rep. 2019;9:9647 pubmed 出版商
Kim H, Lee S, Jeong S, Hong S. Protease-Activated Receptors 2-Antagonist Suppresses Asthma by Inhibiting Reactive Oxygen Species-Thymic Stromal Lymphopoietin Inflammation and Epithelial Tight Junction Degradation. Allergy Asthma Immunol Res. 2019;11:560-571 pubmed 出版商
Wagner T, Beer L, Gschwandtner M, Eckhart L, Kalinina P, Laggner M, et al. The differentiation-associated keratinocyte protein cornifelin contributes to cell-cell adhesion of epidermal and mucosal keratinocytes. J Invest Dermatol. 2019;: pubmed 出版商
Van Itallie C, Lidman K, Tietgens A, Anderson J. Newly synthesized claudins but not occludin are added to the basal side of the tight junction. Mol Biol Cell. 2019;30:1406-1424 pubmed 出版商
Peng J, Leng J, Tian H, Yang T, Fang Y, Feng Q, et al. Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet. Front Pharmacol. 2018;9:1399 pubmed 出版商
Lee S, Cieply B, Yang Y, Peart N, Glaser C, Chan P, et al. Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity. Cell Rep. 2018;25:2417-2430.e5 pubmed 出版商
Chen H, Lu R, Zhang Y, Sun J. Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs. Tissue Barriers. 2018;6:1-13 pubmed 出版商
Steenbergen R, Oti M, Ter Horst R, Tat W, Neufeldt C, Belovodskiy A, et al. Establishing normal metabolism and differentiation in hepatocellular carcinoma cells by culturing in adult human serum. Sci Rep. 2018;8:11685 pubmed 出版商
Rodríguez Uribe G, Serafín Higuera N, Damian Morales G, Cortés Malagón E, García Hernández V, Verdejo Torres O, et al. HPV16-E6 Oncoprotein Activates TGF-β and Wnt/β-Catenin Pathways in the Epithelium-Mesenchymal Transition of Cataracts in a Transgenic Mouse Model. Biomed Res Int. 2018;2018:2847873 pubmed 出版商
Ma Y, Han X, de Castro R, Zhang P, Zhang K, Hu Z, et al. Analysis of the bystander effect in cone photoreceptors via a guided neural network platform. Sci Adv. 2018;4:eaas9274 pubmed 出版商
Shigetomi K, Ono Y, Inai T, Ikenouchi J. Adherens junctions influence tight junction formation via changes in membrane lipid composition. J Cell Biol. 2018;217:2373-2381 pubmed 出版商
Singh A, Sharma S, Pagarware K, Siraji R, Ansari I, Mandal A, et al. Enteropathogenic E. coli effectors EspF and Map independently disrupt tight junctions through distinct mechanisms involving transcriptional and post-transcriptional regulation. Sci Rep. 2018;8:3719 pubmed 出版商
Gilbert A, Chevez Barrios P, Cykowski M. Perineurial-like Cells and EMA Expression in the Suprachoroidal Region of the Human Eye. J Histochem Cytochem. 2018;66:367-375 pubmed 出版商
Cremonini E, Wang Z, Bettaieb A, Adamo A, Daveri E, Mills D, et al. (-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance. Redox Biol. 2018;14:588-599 pubmed 出版商
Shimada H, Satohisa S, Kohno T, Konno T, Takano K, Takahashi S, et al. Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer. Oncol Lett. 2017;14:6776-6782 pubmed 出版商
Lee Y, Lim J, Jeoun U, Min S, Lee E, Kwon S, et al. Lactate-mediated mitoribosomal defects impair mitochondrial oxidative phosphorylation and promote hepatoma cell invasiveness. J Biol Chem. 2017;292:20208-20217 pubmed 出版商
Ahmad R, Rah B, Bastola D, Dhawan P, Singh A. Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching. Sci Rep. 2017;7:5125 pubmed 出版商
Buzza M, Johnson T, Conway G, Martin E, Mukhopadhyay S, Shea Donohue T, et al. Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis. J Biol Chem. 2017;292:10801-10812 pubmed 出版商
Hichino A, Okamoto M, Taga S, Akizuki R, Endo S, Matsunaga T, et al. Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. J Biol Chem. 2017;292:2411-2421 pubmed 出版商
Guo J, Hsu H, Tyan S, Li F, Shew J, Lee W, et al. Serglycin in tumor microenvironment promotes non-small cell lung cancer aggressiveness in a CD44-dependent manner. Oncogene. 2017;36:2457-2471 pubmed 出版商
Banushi B, Forneris F, Straatman Iwanowska A, Strange A, Lyne A, Rogerson C, et al. Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis. Nat Commun. 2016;7:12111 pubmed 出版商
Merino V, Nguyen N, Jin K, Sadik H, Cho S, Korangath P, et al. Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer. Cancer Res. 2016;76:2013-2024 pubmed 出版商
Zwanziger D, Badziong J, Ting S, Moeller L, Schmid K, Siebolts U, et al. The impact of CLAUDIN-1 on follicular thyroid carcinoma aggressiveness. Endocr Relat Cancer. 2015;22:819-30 pubmed 出版商
Lee J, Lee Y, Lim J, Byun H, Park I, Kim G, et al. Mitochondrial Respiratory Dysfunction Induces Claudin-1 Expression via Reactive Oxygen Species-mediated Heat Shock Factor 1 Activation, Leading to Hepatoma Cell Invasiveness. J Biol Chem. 2015;290:21421-31 pubmed 出版商
Barkho B, Monuki E. Proliferation of cultured mouse choroid plexus epithelial cells. PLoS ONE. 2015;10:e0121738 pubmed 出版商
Klein W, Westendorf C, Schmidt A, Conill Cortés M, Rutz C, Blohs M, et al. Defining a conformational consensus motif in cotransin-sensitive signal sequences: a proteomic and site-directed mutagenesis study. PLoS ONE. 2015;10:e0120886 pubmed 出版商
Kreft M, Jerman U, Lasič E, LaniÅ¡nik Rižner T, Hevir Kene N, Peternel L, et al. The characterization of the human nasal epithelial cell line RPMI 2650 under different culture conditions and their optimization for an appropriate in vitro nasal model. Pharm Res. 2015;32:665-79 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
水闸蛋白1多克隆抗体(MH25)
目录# :
71-7800
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
狗, 人类, 小鼠, 大鼠
应用 :
ELISA: 0.1-1.0 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1-2 µg/mL
物种 :
狗, 人类, 小鼠, 大鼠
克隆 :
MH25
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
免疫原 :
A synthetic peptide derived from the C-terminus of the human/mouse Claudin-1 protein.
格式 :
液体
应用w/稀释 :
ELISA: 0.1-1.0 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1-2 µg/mL
别名 :
AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国