产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TGF乙2重组多克隆抗体(12HCLC)
目录 :
710276
规格 :
100微克
价格 :
美国375.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
12HCLC
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 流式细胞仪
更多信息或购买 :
文章摘录数: 1
产品信息
产品类型 :
抗体
产品名称 :
TGF乙2重组多克隆抗体(12HCLC)
目录# :
710276
规格 :
100微克
价格 :
美国375.00
克隆性 :
重组多克隆
纯度 :
蛋白质A
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: Assay-dependent, Western Blot: 1-2 µg/mL
物种 :
人类, 小鼠
克隆 :
12HCLC
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
免疫原 :
Recombinant protein corresponding to amino acids 331–442 of human Transforming Growth Factor Beta 2
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Western Blot: 1-2 µg/mL
别名 :
BB105277; BSC-1 cell growth inhibitor; cetermin; glioblastoma-derived T-cell suppressor factor; G-TSF; LAP; Latency-associated peptide; LDS4; polyergin; prepro-transforming growth factor beta-2; TGF beta 2 protein; TGFB; TGFB2; TGF-B2; Tgfb-2; TGF-beta2; TGF-beta-2; TGFß2; Transforming growth factor; transforming growth factor beta 2; transforming growth factor beta-2; Transforming growth factor beta-2 proprotein; transforming growth factor, beta 2
更多信息或购买 :
公司信息
赛默飞世尔