产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
p38 MAPK甲单克隆抗体(L53F8)
目录 :
82382
规格 :
100微升
价格 :
425美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
L53F8
反应物种 :
人类, 小鼠, 大鼠, 犬, pigs
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
图像
图像 1 :
A549 cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ON-TARGETplus MAPK14 siRNA (Lane 3). Western blot data for Cycolphilin B is included as a control for equal protein loading.
产品信息
产品类型 :
抗体
产品名称 :
p38 MAPK甲单克隆抗体(L53F8)
目录# :
82382
规格 :
100微升
价格 :
425美元
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
Canine, Human, Mouse, Non-human primate, Porcine, Rat, Yeast
应用 :
Flow Cytometry: 1:200, Immunocytochemistry: 1:25, Immunofluorescence: 1:25, Western Blot: 1:1000
物种 :
Canine, Human, Mouse, Non-human primate, Porcine, Rat, Yeast
克隆 :
L53F8
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
The p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation, and other signals. p38 MAPK is relatively inactive in the nonphosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs. There are four isoforms of p38 MAPK, which differ in their tissue expression and affinity for upstream activators and downstream effectors. When cells are exposed to tumor necrosis factor, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 occurs by phosphorylation. Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK. Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factors through phosphorylation.
免疫原 :
重组丝裂原活化蛋白激酶14
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:200, Immunocytochemistry: 1:25, Immunofluorescence: 1:25, Western Blot: 1:1000
别名 :
186F5S; anon-sts23; BG:DS00797.3; CG7393; CG7393 gene product from transcript CG7393-RA; CG7393-PA; CRK1; CSAID-binding protein; Csaids binding protein; CSBP; CSBP1; CSBP2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Dm p38b; Dmel CG7393; Dmel_CG7393; Dmp38b; Dp38; D-p38; D-p38 MAPK; dp38b; D-p38b; EC 2.7.11.24; ERK1; ERT2; ESTS:186F5S; etID18993.8; EXIP; fk28c03; hm:zeh1243; Hog; I79_016605; MAP 14; MAP kinase 1; MAP kinase 14; MAP kinase 14A; MAP kinase 2; MAP kinase MXI2; MAP kinase p38; MAP kinase p38 alpha; MAP kinase p38a; MAP kinase p38alpha; MAP kinase p38b; MAPK; MAPK 14; MAPK 14A; MAPK1 antibody; MAPK14; mapk14a; MAX-interacting protein 2; mitogen activated protein kinase 14; mitogen-activated protein kinase 14; Mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; Mitogen-activated protein kinase p38a; Mitogen-activated protein kinase p38b; MK14; Mpk34C; Mxi2; OTTHUMP00000216563; OTTHUMP00000216566; p38; p38 alpha; p38 alpha/Mxi2; p38 beta; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38 mitogen-activated protein kinase; p38a; p38alpha; p38-alpha; p38alpha Exip; p38b; p38b MAP kinase; p38beta; p38b-PA; p38Hog; p38Kb; p38MAPK; Prkm14; PRKM15; reactive kinase; RK; RP1-179N16.5; SAPK2A; stress-activated p38b MAP kinase; stress-activated protein kinase 2A; tRNA synthetase cofactor p38; wu:fk28c03; zeh1243; zp38a
更多信息或购买 :
公司信息
赛默飞世尔