产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
ELISA/assay
产品名称 :
IL-15 Human Uncoated ELISA Kit
目录 :
88-7620-88
规格 :
10 x 96试验
价格 :
459.00美元
更多信息或购买 :
产品信息
产品类型 :
酶联免疫吸附测定
目录号 :
88-7620-88
类别 :
酶联免疫吸附试剂盒
靶标 :
IL-15
产品名称 :
IL-15 Human Uncoated ELISA Kit
描述 :
IL-15 (Interleukin 15 ) is a cytokine that regulates T and natural killer cell activation and proliferation. IL-15 and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. IL-15 induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules. As such, IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases. Further, IL-15 is a widely expressed pro-inflammatory cytokine and has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases. Emerging data suggest that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes.
同义词 :
AI503618;白细胞介素15;白细胞介素-15;IL-15;ILN;白细胞介素;白细胞介素15;Interleukin15;白细胞介素15;MGC9721;M-IL
价格(美元) :
459.00美元
规格 :
10 x 96试验
物种活性 :
人类
应用 :
酶联免疫吸附测定
储存 :
2-8°C
检测范围 :
20-2,500 pg/mL
样品类型 :
Plasma, 100 µL Serum, 100 µL Supernatant, 100 µL
Assay Length :
1小时45分钟
提示 :
This product is for research use only.
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国