产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
转铁蛋白受体单克隆抗体(236-15375)
目录 :
A-11130
规格 :
50微克
价格 :
美国219.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
236-15375
反应物种 :
African green monkey, 人类, 小鼠, 猕猴
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
文章摘录数: 15
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 3f
Burr M, Sparbier C, Chan Y, Williamson J, Woods K, Beavis P, et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity. Nature. 2017;549:101-105 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 3c
Larson C, Heinzen R. High-Content Imaging Reveals Expansion of the Endosomal Compartment during Coxiella burnetii Parasitophorous Vacuole Maturation. Front Cell Infect Microbiol. 2017;7:48 pubmed 出版商
  • 免疫细胞化学; 人类; 图 8a
Blagojević Zagorac G, Mahmutefendić H, Macesic S, Karleuša L, Lucin P. Quantitative Analysis of Endocytic Recycling of Membrane Proteins by Monoclonal Antibody-Based Recycling Assays. J Cell Physiol. 2017;232:463-476 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Atkin G, Moore S, Lu Y, Nelson R, Tipper N, Rajpal G, et al. Loss of F-box only protein 2 (Fbxo2) disrupts levels and localization of select NMDA receptor subunits, and promotes aberrant synaptic connectivity. J Neurosci. 2015;35:6165-78 pubmed 出版商
  • 免疫沉淀; 人类; 图 6a
Fennessey C, Sheng J, Rubin D, McClain M. Oligomerization of Clostridium perfringens epsilon toxin is dependent upon caveolins 1 and 2. PLoS ONE. 2012;7:e46866 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
Eyster C, Cole N, Petersen S, Viswanathan K, Fruh K, Donaldson J. MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation. Mol Biol Cell. 2011;22:3218-30 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Takenouchi T, Nakai M, Iwamaru Y, Sugama S, Tsukimoto M, Fujita M, et al. The activation of P2X7 receptor impairs lysosomal functions and stimulates the release of autophagolysosomes in microglial cells. J Immunol. 2009;182:2051-62 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6
Kunita R, Otomo A, Mizumura H, Suzuki Utsunomiya K, Hadano S, Ikeda J. The Rab5 activator ALS2/alsin acts as a novel Rac1 effector through Rac1-activated endocytosis. J Biol Chem. 2007;282:16599-611 pubmed
  • 免疫细胞化学; 人类; 图 4C
Fili N, Calleja V, Woscholski R, Parker P, Larijani B. Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting. Proc Natl Acad Sci U S A. 2006;103:15473-8 pubmed
  • 免疫印迹; African green monkey; 图 1
Tanos B, Pendergast A. Abl tyrosine kinase regulates endocytosis of the epidermal growth factor receptor. J Biol Chem. 2006;281:32714-23 pubmed
  • 免疫细胞化学; 小鼠
Brown L, Harris D. Copper and zinc cause delivery of the prion protein from the plasma membrane to a subset of early endosomes and the Golgi. J Neurochem. 2003;87:353-63 pubmed
  • 免疫印迹; 猕猴; 图 3
Ashbourne Excoffon K, Moninger T, Zabner J. The coxsackie B virus and adenovirus receptor resides in a distinct membrane microdomain. J Virol. 2003;77:2559-67 pubmed
Wevers N, Kasi D, Gray T, Wilschut K, Smith B, van Vught R, et al. A perfused human blood-brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport. Fluids Barriers CNS. 2018;15:23 pubmed 出版商
Wikström K, Reid H, Hill M, English K, O Keeffe M, Kimbembe C, et al. Recycling of the human prostacyclin receptor is regulated through a direct interaction with Rab11a GTPase. Cell Signal. 2008;20:2332-46 pubmed 出版商
Laftah A, Sharma N, Brookes M, McKie A, Simpson R, Iqbal T, et al. Tumour necrosis factor alpha causes hypoferraemia and reduced intestinal iron absorption in mice. Biochem J. 2006;397:61-7 pubmed
产品信息
产品类型 :
抗体
产品名称 :
转铁蛋白受体单克隆抗体(236-15375)
目录# :
A-11130
规格 :
50微克
价格 :
美国219.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunocytochemistry: 1-2 µg/mL
物种 :
人类
克隆 :
236-15375
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
免疫原 :
人类转铁蛋白受体
格式 :
冻干
应用w/稀释 :
Immunocytochemistry: 1-2 µg/mL
别名 :
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国