产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
HuC/HuD Monoclonal Antibody (16A11), Biotin
目录 :
A-21272
规格 :
100µg
价格 :
美国408
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
16A11
反应物种 :
豚鼠, 豚鼠, 人类, 小鼠, 大鼠, pigs , 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:200; 图 1a
Brown I, Gulbransen B. The antioxidant glutathione protects against enteric neuron death in situ, but its depletion is protective during colitis. Am J Physiol Gastrointest Liver Physiol. 2018;314:G39-G52 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 2
Wiley L, Burnight E, DeLuca A, Anfinson K, Cranston C, Kaalberg E, et al. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep. 2016;6:30742 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 2
Bubenheimer R, Brown I, Fried D, McClain J, Gulbransen B. Sirtuin-3 Is Expressed by Enteric Neurons but It Does not Play a Major Role in Their Regulation of Oxidative Stress. Front Cell Neurosci. 2016;10:73 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 表 1
Brown I, McClain J, Watson R, Patel B, Gulbransen B. Enteric glia mediate neuron death in colitis through purinergic pathways that require connexin-43 and nitric oxide. Cell Mol Gastroenterol Hepatol. 2016;2:77-91 pubmed
  • 免疫组化; 斑马鱼; 1:800; 图 1a
Schill E, Lake J, Tusheva O, Nagy N, Bery S, Foster L, et al. Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. Dev Biol. 2016;409:473-88 pubmed 出版商
  • 免疫细胞化学; pigs ; 1:100; 图 5
Mazzuoli Weber G, Schemann M. Mechanosensitive enteric neurons in the guinea pig gastric corpus. Front Cell Neurosci. 2015;9:430 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1
Avetisyan M, Wang H, Schill E, Bery S, Grider J, Hassell J, et al. Hepatocyte Growth Factor and MET Support Mouse Enteric Nervous System Development, the Peristaltic Response, and Intestinal Epithelial Proliferation in Response to Injury. J Neurosci. 2015;35:11543-58 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 s13
Thys A, Vandenberghe P, Hague P, Klein O, Erneux C, Vanderwinden J. Hyperplasia of interstitial cells of cajal in sprouty homolog 4 deficient mice. PLoS ONE. 2015;10:e0124861 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:600; 图 1
Voss U, Ekblad E. Lipopolysaccharide-induced loss of cultured rat myenteric neurons - role of AMP-activated protein kinase. PLoS ONE. 2014;9:e114044 pubmed 出版商
  • 免疫组化; 人类
Walstab J, Wohlfarth C, Hovius R, Schmitteckert S, Roth R, Lasitschka F, et al. Natural compounds boldine and menthol are antagonists of human 5-HT3 receptors: implications for treating gastrointestinal disorders. Neurogastroenterol Motil. 2014;26:810-20 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:600
Voss U, Turesson M, Robaye B, Boeynaems J, Olde B, Erlinge D, et al. The enteric nervous system of P2Y13 receptor null mice is resistant against high-fat-diet- and palmitic-acid-induced neuronal loss. Purinergic Signal. 2014;10:455-64 pubmed 出版商
  • 免疫组化; 小鼠; 1:600; 图 1
Voss U, Sand E, Olde B, Ekblad E. Enteric neuropathy can be induced by high fat diet in vivo and palmitic acid exposure in vitro. PLoS ONE. 2013;8:e81413 pubmed 出版商
  • 免疫组化; 小鼠; 图 5
Lake J, Tusheva O, Graham B, Heuckeroth R. Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis. J Clin Invest. 2013;123:4875-87 pubmed
  • 免疫组化; 小鼠; 1:250; 图 1
Wright Jin E, Grider J, Duester G, Heuckeroth R. Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function. Dev Biol. 2013;381:28-37 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4
Shaham O, Gueta K, Mor E, Oren Giladi P, Grinberg D, Xie Q, et al. Pax6 regulates gene expression in the vertebrate lens through miR-204. PLoS Genet. 2013;9:e1003357 pubmed 出版商
  • 免疫组化; 豚鼠; 1:100; 图 2
Giaroni C, Marchet S, Carpanese E, Prandoni V, Oldrini R, Bartolini B, et al. Role of neuronal and inducible nitric oxide synthases in the guinea pig ileum myenteric plexus during in vitro ischemia and reperfusion. Neurogastroenterol Motil. 2013;25:e114-26 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 1
Moreira M, Brehmer A, de Oliveira E, Neto S, Luquetti A, Bueno L, et al. Regenerative process evaluation of neuronal subclasses in chagasic patients with megacolon. Hum Immunol. 2013;74:181-8 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:20; 图 7
Gross E, Gershon M, Margolis K, Gertsberg Z, Li Z, Cowles R. Neuronal serotonin regulates growth of the intestinal mucosa in mice. Gastroenterology. 2012;143:408-17.e2 pubmed 出版商
  • 免疫组化; 小鼠; 1:250; 图 3
Viader A, Wright Jin E, Vohra B, Heuckeroth R, Milbrandt J. Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction. PLoS ONE. 2011;6:e27727 pubmed 出版商
  • 免疫组化; 小鼠; 1:250; 图 3
Freyer L, Aggarwal V, Morrow B. Dual embryonic origin of the mammalian otic vesicle forming the inner ear. Development. 2011;138:5403-14 pubmed 出版商
  • 免疫组化; 大鼠; 1:1000; 图 4
Vera G, Castillo M, Cabezos P, Chiarlone A, Martin M, Gori A, et al. Enteric neuropathy evoked by repeated cisplatin in the rat. Neurogastroenterol Motil. 2011;23:370-8, e162-3 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:100
Kapeller J, Möller D, Lasitschka F, Autschbach F, Hovius R, Rappold G, et al. Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E. J Comp Neurol. 2011;519:420-32 pubmed 出版商
  • 免疫组化; pigs ; 1:100; 图 1
Giaroni C, Zanetti E, Giuliani D, Oldrini R, Marchet S, Moro E, et al. Protein kinase C modulates NMDA receptors in the myenteric plexus of the guinea pig ileum during in vitro ischemia and reperfusion. Neurogastroenterol Motil. 2011;23:e91-103 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50
CHALAZONITIS A, D Autréaux F, Pham T, Kessler J, Gershon M. Bone morphogenetic proteins regulate enteric gliogenesis by modulating ErbB3 signaling. Dev Biol. 2011;350:64-79 pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼; 1:500
Ramachandran R, Reifler A, Parent J, Goldman D. Conditional gene expression and lineage tracing of tuba1a expressing cells during zebrafish development and retina regeneration. J Comp Neurol. 2010;518:4196-212 pubmed 出版商
  • 免疫组化; 豚鼠; 1:1000
Abalo R, Vera G, Rivera A, Moro Rodríguez E, Martín Fontelles M. Postnatal maturation of the gastrointestinal tract: a functional and immunohistochemical study in the guinea-pig ileum at weaning. Neurosci Lett. 2009;467:105-10 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50; 图 2A
Liu M, Kuan Y, Wang J, Hen R, Gershon M. 5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. J Neurosci. 2009;29:9683-99 pubmed 出版商
  • 免疫组化; 人类; 1:50
  • 免疫组化; 豚鼠; 1:50
Hoff S, Zeller F, Von Weyhern C, Wegner M, Schemann M, Michel K, et al. Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody. J Comp Neurol. 2008;509:356-71 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 10 ug/ml; 图 3
Boyer L, Ghoreishi M, Templeman V, Vallance B, Buchan A, Jevon G, et al. Myenteric plexus injury and apoptosis in experimental colitis. Auton Neurosci. 2005;117:41-53 pubmed
Leggieri A, Attanasio C, Palladino A, Cellerino A, Lucini C, Paolucci M, et al. Identification and Expression of Neurotrophin-6 in the Brain of Nothobranchius furzeri: One More Piece in Neurotrophin Research. J Clin Med. 2019;8: pubmed 出版商
Bistoletti M, Caputi V, Baranzini N, Marchesi N, Filpa V, Marsilio I, et al. Antibiotic treatment-induced dysbiosis differently affects BDNF and TrkB expression in the brain and in the gut of juvenile mice. PLoS ONE. 2019;14:e0212856 pubmed 出版商
Larsson S, Voss U. Neuroprotective effects of vitamin D on high fat diet- and palmitic acid-induced enteric neuronal loss in mice. BMC Gastroenterol. 2018;18:175 pubmed 出版商
Delvalle N, Dharshika C, Morales Soto W, Fried D, Gaudette L, Gulbransen B. Communication Between Enteric Neurons, Glia, and Nociceptors Underlies the Effects of Tachykinins on Neuroinflammation. Cell Mol Gastroenterol Hepatol. 2018;6:321-344 pubmed 出版商
Filpa V, Bistoletti M, Caon I, Moro E, Grimaldi A, Moretto P, et al. Changes in hyaluronan deposition in the rat myenteric plexus after experimentally-induced colitis. Sci Rep. 2017;7:17644 pubmed 出版商
Pelletier J, Agonsanou H, Delvalle N, Fausther M, Salem M, Gulbransen B, et al. Generation and characterization of polyclonal and monoclonal antibodies to human NTPDase2 including a blocking antibody. Purinergic Signal. 2017;13:293-304 pubmed 出版商
Filpa V, Carpanese E, Marchet S, Pirrone C, Conti A, Rainero A, et al. Nitric oxide regulates homeoprotein OTX1 and OTX2 expression in the rat myenteric plexus after intestinal ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol. 2017;312:G374-G389 pubmed 出版商
Heanue T, Boesmans W, Bell D, Kawakami K, Vanden Berghe P, Pachnis V. A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity. PLoS Genet. 2016;12:e1006439 pubmed 出版商
Israel J, Cabelguen J, Le Masson G, Oliet S, Ciofi P. Neonatal testosterone suppresses a neuroendocrine pulse generator required for reproduction. Nat Commun. 2014;5:3285 pubmed 出版商
Pacal M, Bremner R. Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012;241:1525-44 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
HuC/HuD Monoclonal Antibody (16A11), Biotin
目录# :
A-21272
规格 :
100µg
价格 :
美国408
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: 1-10 µg/mL, Immunofluorescence: Assay Dependent, Immunohistochemistry: 5-20 µg/mL, Western Blot: 1-5 µg/mL
物种 :
人类
克隆 :
16A11
抗体亚型 :
IgG2b, kappa
储存 :
-20°C
描述 :
Anti-Hu antibodies were originally isolated from a patient with paraneoplastic encephalomyelitis, a rare condition of selective neural tissue injury associated with small cell lung carcinoma. The antibodies bind specifically to antigens present exclusively in neuronal cells and are thus useful as markers of neuronal cells in tissue. The Hu antigen is an RNA-binding protein of the embryonic lethal abnormal visual (Elav) family.
免疫原 :
Human HuC/HuD neuronal protein.
格式 :
冻干
应用w/稀释 :
ELISA: 1-10 µg/mL, Immunofluorescence: Assay Dependent, Immunohistochemistry: 5-20 µg/mL, Western Blot: 1-5 µg/mL
别名 :
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV like neuron-specific RNA binding protein 3; ELAV like neuron-specific RNA binding protein 4; elavC; ELAVL3; elavl3 protein; ELAVL4; ELAV-like protein 3; ELAV-like protein 4; elav-related C; elav-related D; elrc; elrd; embryonic lethal, abnormal vision-related C; embryonic lethal, abnormal vision-related D; etID309927.3; Hu antigen C; Hu antigen D; Hu-antigen C; Hu-antigen D; HUC; HUCL; HUD; id:ibd1248; Paraneoplastic cerebellar degeneration-associated antigen; Paraneoplastic encephalomyelitis antigen HuD; Paraneoplastic limbic encephalitis antigen 21; PLE21; PNEM; Protein elrD; ribonucleoprotein; RNA-binding protein HuD; wu:fb77b03; wu:fc24h01; zHuC
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国