产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
HuR Monoclonal Antibody (19F12)
目录 :
A-21277
规格 :
100µg
价格 :
399.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
19F12
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:1250; 图 5b
Blanco F, Preet R, Aguado A, Vishwakarma V, Stevens L, Vyas A, et al. Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. Oncotarget. 2016;7:74043-74058 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
Willett M, Pollard H, Vlasak M, Morley S. Localization of ribosomes and translation initiation factors to talin/beta3-integrin-enriched adhesion complexes in spreading and migrating mammalian cells. Biol Cell. 2010;102:265-76 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Trojanowicz B, Brodauf L, Sekulla C, Lorenz K, Finke R, Dralle H, et al. The role of AUF1 in thyroid carcinoma progression. Endocr Relat Cancer. 2009;16:857-71 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Yi X, Zhou Y, Zheng W, Chambers S. HuR expression in the nucleus correlates with high histological grade and poor disease-free survival in ovarian cancer. Aust N Z J Obstet Gynaecol. 2009;49:93-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1250
  • 免疫细胞化学; 人类; 1:250
Young L, Sanduja S, Bemis Standoli K, PENA E, Price R, Dixon D. The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. Gastroenterology. 2009;136:1669-79 pubmed 出版商
  • 免疫组化; 人类; 图 2
  • 免疫印迹; 人类; 图 6
Woo H, Zhou Y, Yi X, David C, Zheng W, Gilmore Hebert M, et al. Regulation of non-AU-rich element containing c-fms proto-oncogene expression by HuR in breast cancer. Oncogene. 2009;28:1176-86 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1
  • 免疫细胞化学; 小鼠; 1:1000; 图 2
  • 免疫印迹; 小鼠; 图 3
Tiruchinapalli D, Caron M, Keene J. Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. J Neurochem. 2008;107:1529-43 pubmed 出版商
  • 免疫沉淀; 人类; 图 8
Esnault S, Shen Z, Whitesel E, Malter J. The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes. J Immunol. 2006;177:6999-7006 pubmed
  • 免疫印迹; 人类
Shen Z, Esnault S, Malter J. The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils. Nat Immunol. 2005;6:1280-7 pubmed
  • 免疫细胞化学; 人类
  • 免疫沉淀; 小鼠; 图 6
  • 免疫印迹; 小鼠
Westmark C, Bartleson V, Malter J. RhoB mRNA is stabilized by HuR after UV light. Oncogene. 2005;24:502-11 pubmed
  • 免疫印迹; 人类; 1:10,000; 图 1
Sheflin L, Zou A, Spaulding S. Androgens regulate the binding of endogenous HuR to the AU-rich 3'UTRs of HIF-1alpha and EGF mRNA. Biochem Biophys Res Commun. 2004;322:644-51 pubmed
  • 免疫印迹; 人类; 图 7
Bergmann M, Staples K, Smith S, Barnes P, Newton R. Glucocorticoid inhibition of granulocyte macrophage-colony-stimulating factor from T cells is independent of control by nuclear factor-kappaB and conserved lymphokine element 0. Am J Respir Cell Mol Biol. 2004;30:555-63 pubmed
  • 免疫印迹; 人类; 图 6
Kullmann M, Göpfert U, Siewe B, Hengst L. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR. Genes Dev. 2002;16:3087-99 pubmed
Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, et al. Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018;20:285-295 pubmed 出版商
Peng W, Furuuchi N, Aslanukova L, Huang Y, Brown S, Jiang W, et al. Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development. Mol Cell Biol. 2018;38: pubmed 出版商
Hudy M, Proud D. Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells. Respir Res. 2013;14:88 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
HuR Monoclonal Antibody (19F12)
目录# :
A-21277
规格 :
100µg
价格(美元) :
399.00美元
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Western Blot: 1-5 µg/mL
物种 :
人类
克隆 :
19F12
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
免疫原 :
Human HuR mRNA-binding protein.
格式 :
液体
应用w/稀释 :
Western Blot: 1-5 µg/mL
别名 :
2410055N02Rik; ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV like 1; ELAV like RNA binding protein 1; ELAV like RNA binding protein 1a; ELAV1; elavl1; elavl1 protein; elavl1a; elav-like generic protein; ELAV-like protein 1; elav-related A; elra; embryonic lethal, abnormal vision, drosophila, homolog-like 1; embryonic lethal, abnormal vision-related A; etID309757.2; fa25f08; fb59a02; fc60g02; Hu antigen R; Hua; HU-antigen A; Hu-antigen R; Human antigen R; HuR; MelG; ribonucleoprotein; W91709; wu:fa25f08; wu:fb59a02; wu:fc60g02; zHuA
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国