产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GFAP单克隆抗体(131-17719)
目录 :
A-21282
规格 :
100µL
价格 :
美国349.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
131-17719
反应物种 :
Styela clava, 人类, 小鼠, 大鼠, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, immunohistochemistry - free floating section
更多信息或购买 :
文章摘录数: 27
出版应用/物种/样品/稀释参考文献
  • 免疫细胞化学; 人类; 1:500; 图 3
Ishikawa M, Ohnishi H, Skerleva D, Sakamoto T, Yamamoto N, Hotta A, et al. Transplantation of neurons derived from human iPS cells cultured on collagen matrix into guinea-pig cochleae. J Tissue Eng Regen Med. 2017;11:1766-1778 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 2g
Ellman D, Degn M, Lund M, Clausen B, Novrup H, Flæng S, et al. Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice. Mediators Inflamm. 2016;2016:2684098 pubmed 出版商
  • 免疫组化; 小鼠; 1:250; 图 3f
Choi Y, Lee B, Hansen K, Aten S, Horning P, Wheaton K, et al. Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brain. Neuroscience. 2016;331:1-12 pubmed 出版商
  • immunohistochemistry - free floating section; 大鼠; 1:400
Gorojod R, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler M. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions. Free Radic Biol Med. 2015;87:237-51 pubmed 出版商
  • immunohistochemistry - free floating section; 小鼠; 1:600
Heng Y, Zhou B, Harris L, Harvey T, Smith A, Horne E, et al. NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche. Cereb Cortex. 2015;25:3758-78 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400; 图 2
Novrup H, Bracchi Ricard V, Ellman D, Ricard J, Jain A, Runko E, et al. Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice. J Neuroinflammation. 2014;11:159 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 8
Schneider Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, et al. VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. J Exp Med. 2014;211:1833-46 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200
Chen N, Huang S, Lu C, Chen C, Feng C, Chen C, et al. Flexibilide obtained from cultured soft coral has anti-neuroinflammatory and analgesic effects through the upregulation of spinal transforming growth factor-?1 in neuropathic rats. Mar Drugs. 2014;12:3792-817 pubmed 出版商
  • 免疫印迹; 大鼠
Alarcón Aguilar A, Luna López A, Ventura Gallegos J, Lazzarini R, Galvan Arzate S, González Puertos V, et al. Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment. Neurobiol Aging. 2014;35:1901-12 pubmed 出版商
  • 免疫组化; Styela clava; 1:500
Potter K, Jorfi M, Householder K, Foster E, Weder C, Capadona J. Curcumin-releasing mechanically adaptive intracortical implants improve the proximal neuronal density and blood-brain barrier stability. Acta Biomater. 2014;10:2209-22 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200; 图 4
Chen N, Huang S, Chen W, Chen C, Lu C, Chen C, et al. TGF-?1 attenuates spinal neuroinflammation and the excitatory amino acid system in rats with neuropathic pain. J Pain. 2013;14:1671-85 pubmed 出版商
  • 免疫组化; 大鼠; 1:500; 图 3
Potter K, Buck A, Self W, Callanan M, Sunil S, Capadona J. The effect of resveratrol on neurodegeneration and blood brain barrier stability surrounding intracortical microelectrodes. Biomaterials. 2013;34:7001-15 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Kao C, Hsu Y, Liu J, Lee D, Chung Y, Chiu I. The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. J Neurochem. 2013;126:4-18 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
Huang S, Chen N, Chen W, Hung H, Lee H, Lin Y, et al. Sinularin from indigenous soft coral attenuates nociceptive responses and spinal neuroinflammation in carrageenan-induced inflammatory rat model. Mar Drugs. 2012;10:1899-919 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Chauhan V, Kluttz J, Bost K, Marriott I. Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis. J Immunol. 2011;186:7255-63 pubmed 出版商
  • 免疫组化; 猕猴; 1:500
Sekizawa S, Bechtold A, Tham R, Kott K, Hyde D, Joad J, et al. House-dust mite allergen and ozone exposure decreases histamine H3 receptors in the brainstem respiratory nuclei. Toxicol Appl Pharmacol. 2010;247:204-10 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 3
Wainwright D, Xin J, Mesnard N, Sanders V, Jones K. Toll-like receptor 2 and facial motoneuron survival after facial nerve axotomy. Neurosci Lett. 2010;471:10-4 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:600
Caron E, Sachot C, Prevot V, Bouret S. Distribution of leptin-sensitive cells in the postnatal and adult mouse brain. J Comp Neurol. 2010;518:459-76 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Wainwright D, Xin J, Mesnard N, Beahrs T, Politis C, Sanders V, et al. Exacerbation of facial motoneuron loss after facial nerve axotomy in CCR3-deficient mice. ASN Neuro. 2009;1:e00024 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Wainwright D, Xin J, Mesnard N, Politis C, Sanders V, Jones K. Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice. J Neuroimmunol. 2009;216:66-75 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 4
Rastegar M, Hotta A, Pasceri P, Makarem M, Cheung A, Elliott S, et al. MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy. PLoS ONE. 2009;4:e6810 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:500; 图 1
Franz C, Federici T, Yang J, Backus C, Oh S, Teng Q, et al. Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS. Neurobiol Dis. 2009;33:473-81 pubmed 出版商
  • immunohistochemistry - free floating section; 小鼠; 1:500
  • 免疫细胞化学; 小鼠; 1:500
Puverel S, Nakatani H, Parras C, Soussi Yanicostas N. Prokineticin receptor 2 expression identifies migrating neuroblasts and their subventricular zone transient-amplifying progenitors in adult mice. J Comp Neurol. 2009;512:232-42 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 2
  • 免疫组化-冰冻切片; 小鼠; 图 1
Cebulla C, Jockovich M, Pina Y, Boutrid H, Alegret A, Kulak A, et al. Basic fibroblast growth factor impact on retinoblastoma progression and survival. Invest Ophthalmol Vis Sci. 2008;49:5215-21 pubmed 出版商
  • 流式细胞仪; 小鼠
  • 免疫组化; 小鼠
Balasingam V, Yong V. Attenuation of astroglial reactivity by interleukin-10. J Neurosci. 1996;16:2945-55 pubmed
Jiang S, Xu W, Emery A, Gerfen C, Eiden M, Eiden L. NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain. Eneuro. 2017;4: pubmed 出版商
Zachariah R, Olson C, Ezeonwuka C, Rastegar M. Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes. PLoS ONE. 2012;7:e49763 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
GFAP单克隆抗体(131-17719)
目录# :
A-21282
规格 :
100µL
价格 :
美国349.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent
物种 :
人类
克隆 :
131-17719
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily, and specifically, expressed in astrocytes and certain astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
免疫原 :
蛋白胶质纤维酸性蛋白
格式 :
Liquid
应用w/稀释 :
Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent
别名 :
胶质纤维酸性蛋白, GFAP, GFAP
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
www.thermo.com.cn
1084193588
公司总部: 美国