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NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
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反应物种 :
Styela clava, 人类, 小鼠, 大鼠, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
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文章摘录数: 36
  • 免疫组化-自由浮动切片; 小鼠; 1:1000; 图 s7c
Bhattarai P, Cosacak M, Mashkaryan V, Demir S, Popova S, Govindarajan N, et al. Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain. PLoS Biol. 2020;18:e3000585 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 2g
Ellman D, Degn M, Lund M, Clausen B, Novrup H, Flæng S, et al. Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice. Mediators Inflamm. 2016;2016:2684098 pubmed 出版商
  • 免疫组化; 小鼠; 1:250; 图 3f
Choi Y, Lee B, Hansen K, Aten S, Horning P, Wheaton K, et al. Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brain. Neuroscience. 2016;331:1-12 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 3
Ishikawa M, Ohnishi H, Skerleva D, Sakamoto T, Yamamoto N, Hotta A, et al. Transplantation of neurons derived from human iPS cells cultured on collagen matrix into guinea-pig cochleae. J Tissue Eng Regen Med. 2017;11:1766-1778 pubmed 出版商
  • 免疫组化-自由浮动切片; 大鼠; 1:400
Gorojod R, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler M. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions. Free Radic Biol Med. 2015;87:237-51 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:600
Heng Y, Zhou B, Harris L, Harvey T, Smith A, Horne E, et al. NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche. Cereb Cortex. 2015;25:3758-78 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400; 图 2
Novrup H, Bracchi Ricard V, Ellman D, Ricard J, Jain A, Runko E, et al. Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice. J Neuroinflammation. 2014;11:159 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 8
Schneider Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, et al. VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. J Exp Med. 2014;211:1833-46 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200
Chen N, Huang S, Lu C, Chen C, Feng C, Chen C, et al. Flexibilide obtained from cultured soft coral has anti-neuroinflammatory and analgesic effects through the upregulation of spinal transforming growth factor-?1 in neuropathic rats. Mar Drugs. 2014;12:3792-817 pubmed 出版商
  • 免疫印迹; 大鼠
Alarcón Aguilar A, Luna López A, Ventura Gallegos J, Lazzarini R, Galvan Arzate S, González Puertos V, et al. Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment. Neurobiol Aging. 2014;35:1901-12 pubmed 出版商
  • 免疫组化; Styela clava; 1:500
Potter K, Jorfi M, Householder K, Foster E, Weder C, Capadona J. Curcumin-releasing mechanically adaptive intracortical implants improve the proximal neuronal density and blood-brain barrier stability. Acta Biomater. 2014;10:2209-22 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200; 图 4
Chen N, Huang S, Chen W, Chen C, Lu C, Chen C, et al. TGF-?1 attenuates spinal neuroinflammation and the excitatory amino acid system in rats with neuropathic pain. J Pain. 2013;14:1671-85 pubmed 出版商
  • 免疫组化; 大鼠; 1:500; 图 3
Potter K, Buck A, Self W, Callanan M, Sunil S, Capadona J. The effect of resveratrol on neurodegeneration and blood brain barrier stability surrounding intracortical microelectrodes. Biomaterials. 2013;34:7001-15 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Kao C, Hsu Y, Liu J, Lee D, Chung Y, Chiu I. The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. J Neurochem. 2013;126:4-18 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
Huang S, Chen N, Chen W, Hung H, Lee H, Lin Y, et al. Sinularin from indigenous soft coral attenuates nociceptive responses and spinal neuroinflammation in carrageenan-induced inflammatory rat model. Mar Drugs. 2012;10:1899-919 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Chauhan V, Kluttz J, Bost K, Marriott I. Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis. J Immunol. 2011;186:7255-63 pubmed 出版商
  • 免疫组化; 猕猴; 1:500
Sekizawa S, Bechtold A, Tham R, Kott K, Hyde D, Joad J, et al. House-dust mite allergen and ozone exposure decreases histamine H3 receptors in the brainstem respiratory nuclei. Toxicol Appl Pharmacol. 2010;247:204-10 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 3
Wainwright D, Xin J, Mesnard N, Sanders V, Jones K. Toll-like receptor 2 and facial motoneuron survival after facial nerve axotomy. Neurosci Lett. 2010;471:10-4 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:600
Caron E, Sachot C, Prevot V, Bouret S. Distribution of leptin-sensitive cells in the postnatal and adult mouse brain. J Comp Neurol. 2010;518:459-76 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Wainwright D, Xin J, Mesnard N, Beahrs T, Politis C, Sanders V, et al. Exacerbation of facial motoneuron loss after facial nerve axotomy in CCR3-deficient mice. ASN Neuro. 2009;1:e00024 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Wainwright D, Xin J, Mesnard N, Politis C, Sanders V, Jones K. Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice. J Neuroimmunol. 2009;216:66-75 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 4
Rastegar M, Hotta A, Pasceri P, Makarem M, Cheung A, Elliott S, et al. MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy. PLoS ONE. 2009;4:e6810 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:500; 图 1
Franz C, Federici T, Yang J, Backus C, Oh S, Teng Q, et al. Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS. Neurobiol Dis. 2009;33:473-81 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:500
  • 免疫细胞化学; 小鼠; 1:500
Puverel S, Nakatani H, Parras C, Soussi Yanicostas N. Prokineticin receptor 2 expression identifies migrating neuroblasts and their subventricular zone transient-amplifying progenitors in adult mice. J Comp Neurol. 2009;512:232-42 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1
  • 免疫组化-冰冻切片; 人类; 图 2
Cebulla C, Jockovich M, Pina Y, Boutrid H, Alegret A, Kulak A, et al. Basic fibroblast growth factor impact on retinoblastoma progression and survival. Invest Ophthalmol Vis Sci. 2008;49:5215-21 pubmed 出版商
  • 流式细胞仪; 小鼠
  • 免疫组化; 小鼠
Balasingam V, Yong V. Attenuation of astroglial reactivity by interleukin-10. J Neurosci. 1996;16:2945-55 pubmed
Zhang J, Fang S, Song W, Zhang B, Fan W, Jin G, et al. Biological Characterization and Therapeutics for Subscalp Recurrent in Intracranial Glioblastoma. Onco Targets Ther. 2020;13:9085-9099 pubmed 出版商
Zhan X, Guo S, Li Y, Ran H, Huang H, Mi L, et al. Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation. J Exp Med. 2020;217: pubmed 出版商
Ye M, Solarana K, Rafi H, Patel S, Nabili M, Liu Y, et al. Longitudinal Functional Assessment of Brain Injury Induced by High-Intensity Ultrasound Pulse Sequences. Sci Rep. 2019;9:15518 pubmed 出版商
Cheng A, Bouchard Cannon P, Hegazi S, Lowden C, Fung S, Chiang C, et al. SOX2-Dependent Transcription in Clock Neurons Promotes the Robustness of the Central Circadian Pacemaker. Cell Rep. 2019;26:3191-3202.e8 pubmed 出版商
Hauser M, Yan R, Li W, Repina N, Schaffer D, Xu K. The Spectrin-Actin-Based Periodic Cytoskeleton as a Conserved Nanoscale Scaffold and Ruler of the Neural Stem Cell Lineage. Cell Rep. 2018;24:1512-1522 pubmed 出版商
Kaverina N, Borovjagin A, Kadagidze Z, Baryshnikov A, Baryshnikova M, Malin D, et al. Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy. Autophagy. 2017;13:1905-1923 pubmed 出版商
Jiang S, Xu W, Emery A, Gerfen C, Eiden M, Eiden L. NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain. Eneuro. 2017;4: pubmed 出版商
He Z, Xia B, Wang Y, Li J, Feng G, Zhang L, et al. Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening. Cell Rep. 2017;20:2227-2237 pubmed 出版商
Potter Baker K, Ravikumar M, Burke A, Meador W, Householder K, Buck A, et al. A comparison of neuroinflammation to implanted microelectrodes in rat and mouse models. Biomaterials. 2014;35:5637-46 pubmed 出版商
Zachariah R, Olson C, Ezeonwuka C, Rastegar M. Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes. PLoS ONE. 2012;7:e49763 pubmed 出版商
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克隆性 :
纯度 :
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反应物种 :
应用 :
Immunocytochemistry: Assay-dependent
物种 :
克隆 :
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
免疫原 :
格式 :
应用w/稀释 :
Immunocytochemistry: Assay-dependent
别名 :
6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
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公司总部: 美国