产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GFAP单克隆抗体(131-17719), Alexa Fluor系列荧光染料488
目录 :
A-21294
规格 :
50µL
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF488
克隆名称 :
131-17719
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 14
出版应用/物种/样品/稀释参考文献
  • 免疫组化; scFv; 1:1000; 图 7b
Griffith C, Xie M, Qiu W, Sharp A, Ma C, Pan A, et al. Aberrant expression of the pore-forming KATP channel subunit Kir6.2 in hippocampal reactive astrocytes in the 3xTg-AD mouse model and human Alzheimer's disease. Neuroscience. 2016;336:81-101 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 5 ug/ml
Steffensen M, Fenger C, Christensen J, Jørgensen C, Bassi M, Christensen J, et al. Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways. J Virol. 2014;88:14090-104 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400
Ghosh D, Levault K, Brewer G. Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species. Neurobiol Aging. 2014;35:179-90 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 5
Wainwright D, Balyasnikova I, Chang A, Ahmed A, Moon K, Auffinger B, et al. IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival. Clin Cancer Res. 2012;18:6110-21 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 5 ug/ml
Christensen J, Fenger C, Issazadeh Navikas S, Krug A, Liljestrøm P, Goriely S, et al. Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery. J Virol. 2012;86:7384-92 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Furr S, Chauhan V, Moerdyk Schauwecker M, Marriott I. A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells. J Neuroinflammation. 2011;8:99 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1
Wainwright D, Sengupta S, Han Y, Ulasov I, Lesniak M. The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma. PLoS ONE. 2010;5:e15390 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Chauhan V, Furr S, Sterka D, Nelson D, Moerdyk Schauwecker M, Marriott I, et al. Vesicular stomatitis virus infects resident cells of the central nervous system and induces replication-dependent inflammatory responses. Virology. 2010;400:187-96 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Moussaud S, Draheim H. A new method to isolate microglia from adult mice and culture them for an extended period of time. J Neurosci Methods. 2010;187:243-53 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 3
Wainwright D, Xin J, Mesnard N, Sanders V, Jones K. Toll-like receptor 2 and facial motoneuron survival after facial nerve axotomy. Neurosci Lett. 2010;471:10-4 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Wainwright D, Xin J, Mesnard N, Politis C, Sanders V, Jones K. Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice. J Neuroimmunol. 2009;216:66-75 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 5 ug/ml; 图 10
Christensen J, Simonsen S, Fenger C, Sørensen M, Moos T, Christensen J, et al. Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade. J Immunol. 2009;182:1079-87 pubmed
  • 免疫组化-冰冻切片; 小鼠; 1:200
Tang X, Wang Q, Koike M, Cheng D, Goris M, Blankenberg F, et al. Monitoring the protective effects of minocycline treatment with radiolabeled annexin V in an experimental model of focal cerebral ischemia. J Nucl Med. 2007;48:1822-8 pubmed
Brewer G, Boehler M, Leondopulos S, Pan L, Alagapan S, Demarse T, et al. Toward a self-wired active reconstruction of the hippocampal trisynaptic loop: DG-CA3. Front Neural Circuits. 2013;7:165 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
GFAP单克隆抗体(131-17719), Alexa Fluor系列荧光染料488
目录# :
A-21294
规格 :
50µL
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: Assay Dependent
物种 :
人类
克隆 :
131-17719
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark
描述 :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily, and specifically, expressed in astrocytes and certain astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
免疫原 :
蛋白胶质纤维酸性蛋白
格式 :
Liquid
应用w/稀释 :
Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: Assay Dependent
别名 :
胶质纤维酸性蛋白, GFAP, GFAP
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
www.thermo.com.cn
1084193588
公司总部: 美国