产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
α微管蛋白单克隆抗体(236-10501)
目录 :
A11126
规格 :
50微克
价格 :
美国219.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
236-10501
反应物种 :
malaria parasite P. falciparum, Cyrtanthus mackenii, kangaroo, field poppy, African green monkey, Leishmania , 仓鼠, 人类, 小鼠, 大鼠, , fruit fly , 非洲爪蛙
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 123
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 8d
Sierra Potchanant E, Cerabona D, Sater Z, He Y, Sun Z, Gehlhausen J, et al. INPP5E Preserves Genomic Stability through Regulation of Mitosis. Mol Cell Biol. 2017;37: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400; 图 3a
Hamdan M, Jones K, Cheong Y, Lane S. The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis. Sci Rep. 2016;6:36994 pubmed 出版商
  • 免疫组化; fruit fly ; 1:100; 图 s4
Tofangchi A, Fan A, Saif M. Mechanism of Axonal Contractility in Embryonic Drosophila Motor Neurons In Vivo. Biophys J. 2016;111:1519-1527 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Zhuang J, Kamp W, Li J, Liu C, Kang J, Wang P, et al. Forkhead Box O3A (FOXO3) and the Mitochondrial Disulfide Relay Carrier (CHCHD4) Regulate p53 Protein Nuclear Activity in Response to Exercise. J Biol Chem. 2016;291:24819-24827 pubmed
  • 免疫细胞化学; 小鼠; 1:50; 图 7
Busse B, Bezrukov L, Blank P, Zimmerberg J. Resin embedded multicycle imaging (REMI): a tool to evaluate protein domains. Sci Rep. 2016;6:30284 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 2b
Mihajlovic A, Bruce A. Rho-associated protein kinase regulates subcellular localisation of Angiomotin and Hippo-signalling during preimplantation mouse embryo development. Reprod Biomed Online. 2016;33:381-90 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Harwardt T, Lukas S, Zenger M, Reitberger T, Danzer D, Übner T, et al. Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like Response. PLoS Pathog. 2016;12:e1005748 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:250; 图 s5
Elbaz B, Traka M, Kunjamma R, Dukala D, Brosius Lutz A, Anton E, et al. Adenomatous polyposis coli regulates radial axonal sorting and myelination in the PNS. Development. 2016;143:2356-66 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400; 图 6
Camlin N, Sobinoff A, Sutherland J, Beckett E, Jarnicki A, Vanders R, et al. Maternal Smoke Exposure Impairs the Long-Term Fertility of Female Offspring in a Murine Model. Biol Reprod. 2016;94:39 pubmed 出版商
  • 免疫细胞化学; malaria parasite P. falciparum; 1:2000; 图 3
Kono M, Heincke D, Wilcke L, Wong T, Bruns C, Herrmann S, et al. Pellicle formation in the malaria parasite. J Cell Sci. 2016;129:673-80 pubmed 出版商
  • 免疫细胞化学; 人类; 图 8
Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000
Cooper S, Sadok A, Bousgouni V, Bakal C. Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells. Mol Biol Cell. 2015;26:4163-70 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1
Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed 出版商
  • 免疫细胞化学; 小鼠
Omari S, Waters M, Naranian T, Kim K, Perumalsamy A, Chi M, et al. Mcl-1 is a key regulator of the ovarian reserve. Cell Death Dis. 2015;6:e1755 pubmed 出版商
  • 免疫印迹; 人类
Navis A, van Lith S, van Duijnhoven S, de Pooter M, Yetkin Arik B, Wesseling P, et al. Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein. Acta Neuropathol. 2015;130:131-44 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200
Wu L, Russell D, Wong S, Chen M, Tsai T, St John J, et al. Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors. Development. 2015;142:681-91 pubmed 出版商
  • 免疫细胞化学; African green monkey
Ali M, Chuang C, Saif M. Reprogramming cellular phenotype by soft collagen gels. Soft Matter. 2014;10:8829-37 pubmed 出版商
  • 免疫印迹; 小鼠
Strickland A, Rebelo A, Zhang F, Price J, Bolon B, Silva J, et al. Characterization of the mitofusin 2 R94W mutation in a knock-in mouse model. J Peripher Nerv Syst. 2014;19:152-64 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 0.5 ug/ml
Gu L, Talati P, Vogiatzi P, Romero Weaver A, Abdulghani J, Liao Z, et al. Pharmacologic suppression of JAK1/2 by JAK1/2 inhibitor AZD1480 potently inhibits IL-6-induced experimental prostate cancer metastases formation. Mol Cancer Ther. 2014;13:1246-58 pubmed 出版商
  • 免疫印迹; 牛; 图 5, 6
Turner M, Cronin J, Healey G, Sheldon I. Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6. Endocrinology. 2014;155:1453-65 pubmed 出版商
  • 免疫细胞化学; 人类
Proia D, Zhang C, Sequeira M, Jimenez J, He S, Spector N, et al. Preclinical activity profile and therapeutic efficacy of the HSP90 inhibitor ganetespib in triple-negative breast cancer. Clin Cancer Res. 2014;20:413-24 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Tan C, Hagen T. mTORC1 dependent regulation of REDD1 protein stability. PLoS ONE. 2013;8:e63970 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Tan C, Hagen T. Destabilization of CDC6 upon DNA damage is dependent on neddylation but independent of Cullin E3 ligases. Int J Biochem Cell Biol. 2013;45:1489-98 pubmed 出版商
  • 免疫细胞化学; Cyrtanthus mackenii; 1 ug/ml; 图 3
Hirano T, Takagi K, Hoshino Y, Abe T. DNA damage response in male gametes of Cyrtanthus mackenii during pollen tube growth. AoB Plants. 2013;5:plt004 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Navis A, Bourgonje A, Wesseling P, Wright A, Hendriks W, Verrijp K, et al. Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2. PLoS ONE. 2013;8:e58262 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Tan C, Hagen T. Post-translational regulation of mTOR complex 1 in hypoxia and reoxygenation. Cell Signal. 2013;25:1235-44 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200
Lang J, Maeda Y, Bannerman P, Xu J, Horiuchi M, Pleasure D, et al. Adenomatous polyposis coli regulates oligodendroglial development. J Neurosci. 2013;33:3113-30 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Greer Y, Fields A, Brown A, Rubin J. Atypical protein kinase C? is required for Wnt3a-dependent neurite outgrowth and binds to phosphorylated dishevelled 2. J Biol Chem. 2013;288:9438-46 pubmed 出版商
  • 免疫细胞化学; 人类; 1 ug/ml; 图 5
  • 免疫印迹; 人类; 1:1000; 图 s5
Brandhagen B, Tieszen C, Ulmer T, Tracy M, Goyeneche A, Telleria C. Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics. BMC Cancer. 2013;13:35 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
  • 免疫印迹; 人类; 图 1
Hu C, Sethi J, Hagen T. The role of the cullin-5 e3 ubiquitin ligase in the regulation of insulin receptor substrate-1. Biochem Res Int. 2012;2012:282648 pubmed 出版商
  • 免疫细胞化学; 牛; 1:200
Duncan A, Forcina J, Birt A, Townson D. Estrous cycle-dependent changes of Fas expression in the bovine corpus luteum: influence of keratin 8/18 intermediate filaments and cytokines. Reprod Biol Endocrinol. 2012;10:90 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4
Loessner D, Quent V, Kraemer J, Weber E, Hutmacher D, Magdolen V, et al. Combined expression of KLK4, KLK5, KLK6, and KLK7 by ovarian cancer cells leads to decreased adhesion and paclitaxel-induced chemoresistance. Gynecol Oncol. 2012;127:569-78 pubmed 出版商
  • 免疫细胞化学; 小鼠
Holt J, Lane S, Jennings P, Garcia Higuera I, Moreno S, Jones K. APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing. Mol Biol Cell. 2012;23:3970-81 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s7
Gartner S, Liu Y, Natesan S. De novo generation of cells within human nurse macrophages and consequences following HIV-1 infection. PLoS ONE. 2012;7:e40139 pubmed 出版商
  • 免疫印迹; 人类
Dimberg L, Dimberg A, Ivarsson K, Fryknäs M, Rickardson L, Tobin G, et al. Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma. BMC Cancer. 2012;12:318 pubmed 出版商
  • 免疫组化; 大鼠; 1:50; 图 6
Watanabe T, Sakai Y, Koga D, Bochimoto H, Hira Y, Hosaka M, et al. A unique ball-shaped Golgi apparatus in the rat pituitary gonadotrope: its functional implications in relation to the arrangement of the microtubule network. J Histochem Cytochem. 2012;60:588-602 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400
Lane S, Yun Y, Jones K. Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension. Development. 2012;139:1947-55 pubmed 出版商
  • 免疫印迹; 人类
Beriault D, Haddad O, McCuaig J, Robinson Z, Russell D, Lane E, et al. The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes. PLoS ONE. 2012;7:e31320 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Charters G, Stones C, Shelling A, Baguley B, Finlay G. Centrosomal dysregulation in human metastatic melanoma cell lines. Cancer Genet. 2011;204:477-85 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Choo Y, Boh B, Lou J, Eng J, Leck Y, Anders B, et al. Characterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activity. Mol Biol Cell. 2011;22:4706-15 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
He H, Yu F, Sun C, Luo Y. CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes. PLoS ONE. 2011;6:e22088 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Vanderperre B, Staskevicius A, Tremblay G, McCoy M, O Neill M, Cashman N, et al. An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein. FASEB J. 2011;25:2373-86 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Boh B, Smith P, Hagen T. Neddylation-induced conformational control regulates cullin RING ligase activity in vivo. J Mol Biol. 2011;409:136-45 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1
Stern C, Luoma J, Meitzen J, Mermelstein P. Corticotropin releasing factor-induced CREB activation in striatal neurons occurs via a novel G?? signaling pathway. PLoS ONE. 2011;6:e18114 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2
Chang H, Jennings P, Stewart J, Verrills N, Jones K. Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720. J Biol Chem. 2011;286:14705-12 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Chua Y, Boh B, Ponyeam W, Hagen T. Regulation of cullin RING E3 ubiquitin ligases by CAND1 in vivo. PLoS ONE. 2011;6:e16071 pubmed 出版商
  • 免疫印迹; 仓鼠; 图 4
Skalski M, Sharma N, Williams K, Kruspe A, Coppolino M. SNARE-mediated membrane traffic is required for focal adhesion kinase signaling and Src-regulated focal adhesion turnover. Biochim Biophys Acta. 2011;1813:148-58 pubmed 出版商
  • 免疫细胞化学; 仓鼠; 图 4
  • 免疫印迹; 仓鼠; 图 8
Mire C, White J, Whitt M. A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating. PLoS Pathog. 2010;6:e1000994 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
Richter A, Schagdarsurengin U, Rastetter M, Steinmann K, Dammann R. Protein kinase A-mediated phosphorylation of the RASSF1A tumour suppressor at Serine 203 and regulation of RASSF1A function. Eur J Cancer. 2010;46:2986-95 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Leck Y, Choo Y, Tan C, Smith P, Hagen T. Biochemical and cellular effects of inhibiting Nedd8 conjugation. Biochem Biophys Res Commun. 2010;398:588-93 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Yu F, Chai T, He H, Hagen T, Luo Y. Thioredoxin-interacting protein (Txnip) gene expression: sensing oxidative phosphorylation status and glycolytic rate. J Biol Chem. 2010;285:25822-30 pubmed 出版商
  • 免疫组化; Cyrtanthus mackenii; 1 ug/ml; 图 2
Hirano T, Hoshino Y. Sperm dimorphism in terms of nuclear shape and microtubule accumulation in Cyrtanthus mackenii. Sex Plant Reprod. 2010;23:153-62 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Irvine M, Philipsz S, Frausto M, Mijatov B, Gallagher S, Fung C, et al. Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria. Cell Cycle. 2010;9:829-39 pubmed
  • 免疫细胞化学; 小鼠; 1:200
Chang H, Minahan K, Merriman J, Jones K. Calmodulin-dependent protein kinase gamma 3 (CamKIIgamma3) mediates the cell cycle resumption of metaphase II eggs in mouse. Development. 2009;136:4077-81 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Shkarupeta M, Kostrjukova E, Lazarev V, Levitskii S, Basovskii Y, Govorun V. Localization of C. trachomatis Inc proteins in expression of their genes in HeLa cell culture. Bull Exp Biol Med. 2008;146:237-42 pubmed
  • 免疫印迹; 人类; 图 3
Haferkamp S, Becker T, Scurr L, Kefford R, Rizos H. p16INK4a-induced senescence is disabled by melanoma-associated mutations. Aging Cell. 2008;7:733-45 pubmed
  • 免疫细胞化学; 人类; 1:200; 图 7
Kim Y, Park S, Park J. Biomechanical analysis of cancerous and normal cells based on bulge generation in a microfluidic device. Analyst. 2008;133:1432-9 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Nakaya T, Kawai T, Suzuki T. Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells. J Biol Chem. 2008;283:19119-31 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠
Carneiro A, Fragel Madeira L, Silva Neto M, Linden R. A role for CK2 upon interkinetic nuclear migration in the cell cycle of retinal progenitor cells. Dev Neurobiol. 2008;68:620-31 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:40; 图 3
Woost P, Kolb R, Chang C, Finesilver M, Inagami T, Hopfer U. Development of an AT2-deficient proximal tubule cell line for transport studies. In Vitro Cell Dev Biol Anim. 2007;43:352-60 pubmed
  • 免疫细胞化学; 人类; 1:400
Gabet A, Accardi R, Bellopede A, Popp S, Boukamp P, Sylla B, et al. Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin human papillomavirus type 38. FASEB J. 2008;22:622-32 pubmed
  • 免疫细胞化学; kangaroo; 2 ug/ml
Egner A, Geisler C, von Middendorff C, Bock H, Wenzel D, Medda R, et al. Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters. Biophys J. 2007;93:3285-90 pubmed
  • 免疫细胞化学; 人类; 1:200; 图 3
Nishiya T, Kajita E, Horinouchi T, Nishimoto A, Miwa S. Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD88. FEBS Lett. 2007;581:3223-9 pubmed
  • 免疫印迹; 人类; 表 1
Supino R, Favini E, Cuccuru G, Zunino F, Scovassi A. Effect of paclitaxel on intracellular localization of c-Myc and P-c-Myc in prostate carcinoma cell lines. Ann N Y Acad Sci. 2007;1095:175-81 pubmed
  • 免疫组化; field poppy; 1:200; 图 8
Gossot O, Geitmann A. Pollen tube growth: coping with mechanical obstacles involves the cytoskeleton. Planta. 2007;226:405-16 pubmed
  • 免疫印迹; 人类; 图 1
Chew E, Poobalasingam T, Hawkey C, Hagen T. Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization. Cell Signal. 2007;19:1071-80 pubmed
  • 免疫印迹; 小鼠
Wegmüller D, Raineri I, Gross B, Oakeley E, Moroni C. A cassette system to study embryonic stem cell differentiation by inducible RNA interference. Stem Cells. 2007;25:1178-85 pubmed
  • 免疫细胞化学; 人类; 1 ug/ml; 图 1
Henley D, Isbill M, Fernando R, Foster J, Wimalasena J. Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity. Cancer Chemother Pharmacol. 2007;59:235-49 pubmed
  • 免疫细胞化学; Leishmania ; 1:1000; 图 3
Valdes R, Liu W, Ullman B, Landfear S. Comprehensive examination of charged intramembrane residues in a nucleoside transporter. J Biol Chem. 2006;281:22647-55 pubmed
  • 免疫细胞化学; 小鼠; 1:200; 图 1
Sharma M, Leung L, Brocardo M, Henderson J, Flegg C, Henderson B. Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin. J Biol Chem. 2006;281:17140-9 pubmed
  • 免疫细胞化学; 小鼠; 图 6
Hao M, Li X, Rizzo M, Rocheleau J, Dawant B, Piston D. Regulation of two insulin granule populations within the reserve pool by distinct calcium sources. J Cell Sci. 2005;118:5873-84 pubmed
  • 免疫细胞化学; 人类; 图 1
Remacle A, Rozanov D, Baciu P, Chekanov A, Golubkov V, Strongin A. The transmembrane domain is essential for the microtubular trafficking of membrane type-1 matrix metalloproteinase (MT1-MMP). J Cell Sci. 2005;118:4975-84 pubmed
  • 免疫细胞化学; 非洲爪蛙; 图 2
Nascimento A, Roland J, Gelfand V. Pigment cells: a model for the study of organelle transport. Annu Rev Cell Dev Biol. 2003;19:469-91 pubmed
  • 免疫印迹; 人类; 0.4 ug/ml; 图 2
Martin K, Hart C, Liu J, Leung W, Patton W. Simultaneous trichromatic fluorescence detection of proteins on Western blots using an amine-reactive dye in combination with alkaline phosphatase- and horseradish peroxidase-antibody conjugates. Proteomics. 2003;3:1215-27 pubmed
  • 免疫印迹; 人类; 图 6
Ashton A, Ware G, Kaul D, Ware J. Inhibition of tumor necrosis factor alpha-mediated NFkappaB activation and leukocyte adhesion, with enhanced endothelial apoptosis, by G protein-linked receptor (TP) ligands. J Biol Chem. 2003;278:11858-66 pubmed
  • 免疫印迹; 大鼠; 图 3
Rohde G, Wenzel D, Haucke V. A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosis. J Cell Biol. 2002;158:209-14 pubmed
  • 免疫细胞化学; African green monkey; 1:250; 图 3
Errico A, Ballabio A, Rugarli E. Spastin, the protein mutated in autosomal dominant hereditary spastic paraplegia, is involved in microtubule dynamics. Hum Mol Genet. 2002;11:153-63 pubmed
  • 免疫细胞化学; 小鼠; 1:20,000; 图 6g
Hernandez Blazquez F, Joazeiro P, Omori Y, Yamasaki H. Control of intracellular movement of connexins by E-cadherin in murine skin papilloma cells. Exp Cell Res. 2001;270:235-47 pubmed
  • 免疫细胞化学; 小鼠
Gramolini A, Belanger G, Jasmin B. Distinct regions in the 3' untranslated region are responsible for targeting and stabilizing utrophin transcripts in skeletal muscle cells. J Cell Biol. 2001;154:1173-83 pubmed
  • 免疫细胞化学; 仓鼠; 图 6
Vogelsberg Ragaglia V, Bruce J, Richter Landsberg C, Zhang B, Hong M, Trojanowski J, et al. Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells. Mol Biol Cell. 2000;11:4093-104 pubmed
  • 免疫印迹; 人类; 1:20,000
Deloulme J, Assard N, Mbele G, Mangin C, Kuwano R, Baudier J. S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo. J Biol Chem. 2000;275:35302-10 pubmed
  • 免疫印迹; 人类; 图 4
Pryde J, Walker A, Rossi A, Hannah S, Haslett C. Temperature-dependent arrest of neutrophil apoptosis. Failure of Bax insertion into mitochondria at 15 degrees C prevents the release of cytochrome c. J Biol Chem. 2000;275:33574-84 pubmed
  • 免疫印迹; 小鼠; 1:500; 图 5
Berggren K, Steinberg T, Lauber W, Carroll J, Lopez M, Chernokalskaya E, et al. A luminescent ruthenium complex for ultrasensitive detection of proteins immobilized on membrane supports. Anal Biochem. 1999;276:129-43 pubmed
  • 免疫细胞化学; 大鼠; 1:200; 图 2
  • 免疫印迹; 大鼠; 1:12,000; 图 4
Timm S, Titus B, Bernd K, Barroso M. The EF-hand Ca(2+)-binding protein p22 associates with microtubules in an N-myristoylation-dependent manner. Mol Biol Cell. 1999;10:3473-88 pubmed
  • 免疫组化; 牛; 图 7
Panchuk Voloshina N, Bishop Stewart J, Bhalgat M, Millard P, Mao F, Leung W, et al. Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, photostable conjugates. J Histochem Cytochem. 1999;47:1179-88 pubmed
  • 流式细胞仪; 人类; 1:10
Koester S, Schlossman S, Zhang C, Decker S, Bolton W. APO2.7 defines a shared apoptotic-necrotic pathway in a breast tumor hypoxia model. Cytometry. 1998;33:324-32 pubmed
  • 免疫组化; fruit fly ; 图 4
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产品信息
产品类型 :
抗体
产品名称 :
α微管蛋白单克隆抗体(236-10501)
目录# :
A11126
规格 :
50微克
价格 :
美国219.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
牛, 人类, 小鼠
应用 :
Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000-1:5,000
物种 :
牛, 人类, 小鼠
克隆 :
236-10501
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
免疫原 :
牛α微管蛋白
格式 :
冻干
应用w/稀释 :
Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000-1:5,000
别名 :
&agr-tubulin 84B; 1t; a1t; ALPHA 84C; alpha tubulin; alpha tubulin 84B; alpha[[1]] tubulin; alpha[[1]]-tubulin; alpha1; alpha1 tubulin; alpha1t; alpha1tub; alpha1tub84B; alpha1-tubulin; alpha84B; alphaT; alphat-1; alphatub; alpha-tub; alphaTub1; alphatub84; alphaTUB84B; alpha-tub84B; alphaTub84B-PA; alphatubulin; alpha-tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3D; Alpha-tubulin 3E; alpha-tubulin 4; Alpha-tubulin 6; alphaTubulin 84B; alpha-Tubulin 84B; alpha-Tubulin at 84B; alpha-tubulin I; Alpha-tubulin II; alpha-tubulin III; Alpha-tubulin isotype M-alpha-1; alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; alpha-tubulin isotype M-alpha-6; alpha-tubulin TUB1; alpha-tubulin ubiquitous; alphaTubulin84B; Alpha-Tubulin84B; ALS22; anon-EST:Liang-1.59; anon-EST:Liang-2.30; AT25469p; aTub84B; a-tub84B; bA408E5.3; B-ALPHA-1; bcm948; BEST:LD32507; cb944; CG1913; CG1913-PA; chr3R:2914276. 2914416; clone 1.59; clone 2.30; Detyrosinated tubulin alpha-1A chain; Detyrosinated tubulin alpha-1B chain; Detyrosinated tubulin alpha-1C chain; Detyrosinated tubulin alpha-3 chain; Detyrosinated tubulin alpha-3C chain; Detyrosinated tubulin alpha-3D chain; Detyrosinated tubulin alpha-3E chain; DM1alpha; Dmel CG1913; Dmel_CG1913; DTA1; fb22g06; FLJ30169; H2 ALPHA; H2-ALPHA; hum-a-tub1; hum-a-tub2; I79_019110; K-ALPHA-1; l(3)84Bd; l(3)g3; lis3; LOC100726777; LOC100731885; LOC100857858; LOC101118307; LOC106557476; M[a]4; M[a]6; ms(3)nc33; nc33; RGD1565476; similar to alpha-tubulin isoform 1; similar to tubulin alpha 1; T; Talpha1; Talpha1 alpha-tubulin; TBA1_DROME; Testis-specific alpha-tubulin; Tub; Tub 84B; TUB1; Tub1C; Tub84B; TUBA1; Tuba-1; tuba1 protein; TUBA1/3/4; Tuba1a; tuba1a.L; tuba1a-a; tuba1a-b; TUBA1B; TUBA1C; tuba1l; tuba1l2; TUBA2; TUBA3; TUBA3C; TUBA3D; TUBA3E; Tuba4; Tuba4a; TUBA5; Tuba6; tuba8.S; tubA84B; tubal2; Tubalpha1; tubulin; tubulin 1 alpha-chain; tubulin 1alpha; tubulin alpha; tubulin alpha 1a; tubulin alpha 1a L homeolog; tubulin alpha 1b; tubulin alpha 1c; tubulin alpha 3; tubulin alpha 3c; tubulin alpha 3e; tubulin alpha 4a; tubulin alpha 6; tubulin alpha 8 S homeolog; tubulin alpha1; tubulin alpha-1 chain; tubulin alpha1 promoter; Tubulin alpha-1A chain; tubulin alpha-1B chain; Tubulin alpha-1C chain; tubulin alpha-1C chain-like; tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-3C chain; tubulin alpha-3C/D chain; Tubulin alpha-3D chain; Tubulin alpha-3E chain; tubulin alpha-4 chain; Tubulin alpha-4A chain; Tubulin alpha-5 chain; tubulin alpha-5 chain-like; tubulin alpha-6 chain; tubulin alpha-8 chain; tubulin alpha-ubiquitous chain; tubulin B-alpha-1; Tubulin H2-alpha; tubulin K-alpha-1; tubulin(alpha1); tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1, like; tubulin, alpha 1, like 2; tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 1c; tubulin, alpha 2; tubulin, alpha 3c; tubulin, alpha 3e; tubulin, alpha 4; tubulin, alpha 4a; tubulin, alpha 5; tubulin, alpha 6; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous; tubulin1alpha; tubulin84B; Tubulin-alpha1; Unknown (protein for MGC:133894); unnamed protein product; wu:fb22g06; wu:fb37a10; XELAEV_18019849mg; XELAEV_18020901mg; YML085C
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国