产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
α微管蛋白单克隆抗体(236-10501)
目录 :
A11126
规格 :
50微克
价格 :
美国219.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
236-10501
反应物种 :
malaria parasite P. falciparum, Cyrtanthus mackenii, kangaroo, field poppy, African green monkey, Leishmania , 仓鼠, 人类, 小鼠, 大鼠, 牛, fruit fly , 非洲爪蛙
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 123
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| Zhuang J, Kamp W, Li J, Liu C, Kang J, Wang P, et al. Forkhead Box O3A (FOXO3) and the Mitochondrial Disulfide Relay Carrier (CHCHD4) Regulate p53 Protein Nuclear Activity in Response to Exercise. J Biol Chem. 2016;291:24819-24827 pubmed
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| Irvine M, Philipsz S, Frausto M, Mijatov B, Gallagher S, Fung C, et al. Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria. Cell Cycle. 2010;9:829-39 pubmed
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| Shkarupeta M, Kostrjukova E, Lazarev V, Levitskii S, Basovskii Y, Govorun V. Localization of C. trachomatis Inc proteins in expression of their genes in HeLa cell culture. Bull Exp Biol Med. 2008;146:237-42 pubmed
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| Haferkamp S, Becker T, Scurr L, Kefford R, Rizos H. p16INK4a-induced senescence is disabled by melanoma-associated mutations. Aging Cell. 2008;7:733-45 pubmed
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| Woost P, Kolb R, Chang C, Finesilver M, Inagami T, Hopfer U. Development of an AT2-deficient proximal tubule cell line for transport studies. In Vitro Cell Dev Biol Anim. 2007;43:352-60 pubmed
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| Gabet A, Accardi R, Bellopede A, Popp S, Boukamp P, Sylla B, et al. Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin human papillomavirus type 38. FASEB J. 2008;22:622-32 pubmed
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| Egner A, Geisler C, von Middendorff C, Bock H, Wenzel D, Medda R, et al. Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters. Biophys J. 2007;93:3285-90 pubmed
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| Nishiya T, Kajita E, Horinouchi T, Nishimoto A, Miwa S. Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD88. FEBS Lett. 2007;581:3223-9 pubmed
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| Supino R, Favini E, Cuccuru G, Zunino F, Scovassi A. Effect of paclitaxel on intracellular localization of c-Myc and P-c-Myc in prostate carcinoma cell lines. Ann N Y Acad Sci. 2007;1095:175-81 pubmed
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| Gossot O, Geitmann A. Pollen tube growth: coping with mechanical obstacles involves the cytoskeleton. Planta. 2007;226:405-16 pubmed
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| Chew E, Poobalasingam T, Hawkey C, Hagen T. Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization. Cell Signal. 2007;19:1071-80 pubmed
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| Wegmüller D, Raineri I, Gross B, Oakeley E, Moroni C. A cassette system to study embryonic stem cell differentiation by inducible RNA interference. Stem Cells. 2007;25:1178-85 pubmed
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| Henley D, Isbill M, Fernando R, Foster J, Wimalasena J. Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity. Cancer Chemother Pharmacol. 2007;59:235-49 pubmed
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| Valdes R, Liu W, Ullman B, Landfear S. Comprehensive examination of charged intramembrane residues in a nucleoside transporter. J Biol Chem. 2006;281:22647-55 pubmed
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| Sharma M, Leung L, Brocardo M, Henderson J, Flegg C, Henderson B. Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin. J Biol Chem. 2006;281:17140-9 pubmed
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| Hao M, Li X, Rizzo M, Rocheleau J, Dawant B, Piston D. Regulation of two insulin granule populations within the reserve pool by distinct calcium sources. J Cell Sci. 2005;118:5873-84 pubmed
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| Remacle A, Rozanov D, Baciu P, Chekanov A, Golubkov V, Strongin A. The transmembrane domain is essential for the microtubular trafficking of membrane type-1 matrix metalloproteinase (MT1-MMP). J Cell Sci. 2005;118:4975-84 pubmed
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| Nascimento A, Roland J, Gelfand V. Pigment cells: a model for the study of organelle transport. Annu Rev Cell Dev Biol. 2003;19:469-91 pubmed
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| Martin K, Hart C, Liu J, Leung W, Patton W. Simultaneous trichromatic fluorescence detection of proteins on Western blots using an amine-reactive dye in combination with alkaline phosphatase- and horseradish peroxidase-antibody conjugates. Proteomics. 2003;3:1215-27 pubmed
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| Ashton A, Ware G, Kaul D, Ware J. Inhibition of tumor necrosis factor alpha-mediated NFkappaB activation and leukocyte adhesion, with enhanced endothelial apoptosis, by G protein-linked receptor (TP) ligands. J Biol Chem. 2003;278:11858-66 pubmed
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| Rohde G, Wenzel D, Haucke V. A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosis. J Cell Biol. 2002;158:209-14 pubmed
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| Errico A, Ballabio A, Rugarli E. Spastin, the protein mutated in autosomal dominant hereditary spastic paraplegia, is involved in microtubule dynamics. Hum Mol Genet. 2002;11:153-63 pubmed
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| Hernandez Blazquez F, Joazeiro P, Omori Y, Yamasaki H. Control of intracellular movement of connexins by E-cadherin in murine skin papilloma cells. Exp Cell Res. 2001;270:235-47 pubmed
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| Gramolini A, Belanger G, Jasmin B. Distinct regions in the 3' untranslated region are responsible for targeting and stabilizing utrophin transcripts in skeletal muscle cells. J Cell Biol. 2001;154:1173-83 pubmed
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| Vogelsberg Ragaglia V, Bruce J, Richter Landsberg C, Zhang B, Hong M, Trojanowski J, et al. Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells. Mol Biol Cell. 2000;11:4093-104 pubmed
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| Deloulme J, Assard N, Mbele G, Mangin C, Kuwano R, Baudier J. S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo. J Biol Chem. 2000;275:35302-10 pubmed
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| Pryde J, Walker A, Rossi A, Hannah S, Haslett C. Temperature-dependent arrest of neutrophil apoptosis. Failure of Bax insertion into mitochondria at 15 degrees C prevents the release of cytochrome c. J Biol Chem. 2000;275:33574-84 pubmed
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| Berggren K, Steinberg T, Lauber W, Carroll J, Lopez M, Chernokalskaya E, et al. A luminescent ruthenium complex for ultrasensitive detection of proteins immobilized on membrane supports. Anal Biochem. 1999;276:129-43 pubmed
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| Timm S, Titus B, Bernd K, Barroso M. The EF-hand Ca(2+)-binding protein p22 associates with microtubules in an N-myristoylation-dependent manner. Mol Biol Cell. 1999;10:3473-88 pubmed
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| Panchuk Voloshina N, Bishop Stewart J, Bhalgat M, Millard P, Mao F, Leung W, et al. Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, photostable conjugates. J Histochem Cytochem. 1999;47:1179-88 pubmed
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| Koester S, Schlossman S, Zhang C, Decker S, Bolton W. APO2.7 defines a shared apoptotic-necrotic pathway in a breast tumor hypoxia model. Cytometry. 1998;33:324-32 pubmed
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| Hime G, Saint R. Zygotic expression of the pebble locus is required for cytokinesis during the postblastoderm mitoses of Drosophila. Development. 1992;114:165-71 pubmed
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Modamio Hoybjor S, Mencia A, Goodyear R, del Castillo I, Richardson G, Moreno F, et al. A mutation in CCDC50, a gene encoding an effector of epidermal growth factor-mediated cell signaling, causes progressive hearing loss. Am J Hum Genet. 2007;80:1076-89 pubmed
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Burstein E, Hoberg J, Wilkinson A, Rumble J, Csomos R, Komarck C, et al. COMMD proteins, a novel family of structural and functional homologs of MURR1. J Biol Chem. 2005;280:22222-32 pubmed
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Babcock H, Chen C, Zhuang X. Using single-particle tracking to study nuclear trafficking of viral genes. Biophys J. 2004;87:2749-58 pubmed
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Hasegawa H, Zinsser S, Rhee Y, Vik Mo E, Davanger S, Hay J. Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain. Mol Biol Cell. 2003;14:698-720 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
α微管蛋白单克隆抗体(236-10501)
目录# :
A11126
规格 :
50微克
价格 :
美国219.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
牛, 人类, 小鼠
应用 :
Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000-1:5,000
物种 :
牛, 人类, 小鼠
克隆 :
236-10501
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
免疫原 :
牛α微管蛋白
格式 :
冻干
应用w/稀释 :
Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000-1:5,000
别名 :
&agr-tubulin 84B; 1t; a1t; ALPHA 84C; alpha tubulin; alpha tubulin 84B; alpha[[1]] tubulin; alpha[[1]]-tubulin; alpha1; alpha1 tubulin; alpha1t; alpha1tub; alpha1tub84B; alpha1-tubulin; alpha84B; alphaT; alphat-1; alphatub; alpha-tub; alphaTub1; alphatub84; alphaTUB84B; alpha-tub84B; alphaTub84B-PA; alphatubulin; alpha-tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3D; Alpha-tubulin 3E; alpha-tubulin 4; Alpha-tubulin 6; alphaTubulin 84B; alpha-Tubulin 84B; alpha-Tubulin at 84B; alpha-tubulin I; Alpha-tubulin II; alpha-tubulin III; Alpha-tubulin isotype M-alpha-1; alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; alpha-tubulin isotype M-alpha-6; alpha-tubulin TUB1; alpha-tubulin ubiquitous; alphaTubulin84B; Alpha-Tubulin84B; ALS22; anon-EST:Liang-1.59; anon-EST:Liang-2.30; AT25469p; aTub84B; a-tub84B; bA408E5.3; B-ALPHA-1; bcm948; BEST:LD32507; cb944; CG1913; CG1913-PA; chr3R:2914276. 2914416; clone 1.59; clone 2.30; Detyrosinated tubulin alpha-1A chain; Detyrosinated tubulin alpha-1B chain; Detyrosinated tubulin alpha-1C chain; Detyrosinated tubulin alpha-3 chain; Detyrosinated tubulin alpha-3C chain; Detyrosinated tubulin alpha-3D chain; Detyrosinated tubulin alpha-3E chain; DM1alpha; Dmel CG1913; Dmel_CG1913; DTA1; fb22g06; FLJ30169; H2 ALPHA; H2-ALPHA; hum-a-tub1; hum-a-tub2; I79_019110; K-ALPHA-1; l(3)84Bd; l(3)g3; lis3; LOC100726777; LOC100731885; LOC100857858; LOC101118307; LOC106557476; M[a]4; M[a]6; ms(3)nc33; nc33; RGD1565476; similar to alpha-tubulin isoform 1; similar to tubulin alpha 1; T; Talpha1; Talpha1 alpha-tubulin; TBA1_DROME; Testis-specific alpha-tubulin; Tub; Tub 84B; TUB1; Tub1C; Tub84B; TUBA1; Tuba-1; tuba1 protein; TUBA1/3/4; Tuba1a; tuba1a.L; tuba1a-a; tuba1a-b; TUBA1B; TUBA1C; tuba1l; tuba1l2; TUBA2; TUBA3; TUBA3C; TUBA3D; TUBA3E; Tuba4; Tuba4a; TUBA5; Tuba6; tuba8.S; tubA84B; tubal2; Tubalpha1; tubulin; tubulin 1 alpha-chain; tubulin 1alpha; tubulin alpha; tubulin alpha 1a; tubulin alpha 1a L homeolog; tubulin alpha 1b; tubulin alpha 1c; tubulin alpha 3; tubulin alpha 3c; tubulin alpha 3e; tubulin alpha 4a; tubulin alpha 6; tubulin alpha 8 S homeolog; tubulin alpha1; tubulin alpha-1 chain; tubulin alpha1 promoter; Tubulin alpha-1A chain; tubulin alpha-1B chain; Tubulin alpha-1C chain; tubulin alpha-1C chain-like; tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-3C chain; tubulin alpha-3C/D chain; Tubulin alpha-3D chain; Tubulin alpha-3E chain; tubulin alpha-4 chain; Tubulin alpha-4A chain; Tubulin alpha-5 chain; tubulin alpha-5 chain-like; tubulin alpha-6 chain; tubulin alpha-8 chain; tubulin alpha-ubiquitous chain; tubulin B-alpha-1; Tubulin H2-alpha; tubulin K-alpha-1; tubulin(alpha1); tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1, like; tubulin, alpha 1, like 2; tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 1c; tubulin, alpha 2; tubulin, alpha 3c; tubulin, alpha 3e; tubulin, alpha 4; tubulin, alpha 4a; tubulin, alpha 5; tubulin, alpha 6; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous; tubulin1alpha; tubulin84B; Tubulin-alpha1; Unknown (protein for MGC:133894); unnamed protein product; wu:fb22g06; wu:fb37a10; XELAEV_18019849mg; XELAEV_18020901mg; YML085C
更多信息或购买 :
公司信息
赛默飞世尔