产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD31 Monoclonal Antibody (390), Alexa Fluor™ 647
目录 :
A14716
规格 :
25微克
价格 :
美国142
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
AF647
克隆名称 :
390
反应物种 :
小鼠
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 4
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:1000; 图 2a
Kameritsch P, Singer M, Nuernbergk C, Ríos N, Reyes A, Schmidt K, et al. The mitochondrial thioredoxin reductase system (TrxR2) in vascular endothelium controls peroxynitrite levels and tissue integrity. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
Pulido R, Munji R, Chan T, Quirk C, Weiner G, Weger B, et al. Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes. Neuron. 2020;108:937-952.e7 pubmed 出版商
Munji R, Soung A, Weiner G, Sohet F, Semple B, Trivedi A, et al. Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module. Nat Neurosci. 2019;22:1892-1902 pubmed 出版商
Veerman K, Tardiveau C, Martins F, Coudert J, Girard J. Single-Cell Analysis Reveals Heterogeneity of High Endothelial Venules and Different Regulation of Genes Controlling Lymphocyte Entry to Lymph Nodes. Cell Rep. 2019;26:3116-3131.e5 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD31 Monoclonal Antibody (390), Alexa Fluor™ 647
目录# :
A14716
规格 :
25微克
价格 :
美国142
克隆性 :
单克隆
纯度 :
纯化
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.2 µg/1x10^6 cells
物种 :
小鼠
克隆 :
390
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark
描述 :
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
免疫原 :
小鼠白细胞 细胞株32D
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.2 µg/1x10^6 cells
别名 :
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国