产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
人类神经生长因子重组蛋白
目录 :
A42576
规格 :
5 x 50微克
价格 :
美国349
更多信息或购买 :
产品信息
产品类型 :
蛋白
产品名称 :
人类神经生长因子重组蛋白
目录# :
A42576
规格 :
5 x 50微克
价格 :
美国349
克隆性 :
重组
纯度 :
纯化
宿主 :
CHO细胞
反应物种 :
人类
应用 :
Control: Assay-dependent, ELISA: Assay-dependent, Functional assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类
储存 :
-20°C
描述 :
Nerve growth factor (NGF) influences the survival and differentiation of a variety of neuronal and nonneuronal cells. The actions of this polypeptide result from binding to specific cell surface receptors which are present as both high and low affinity sites. Although both types of receptor bind NGF only the high affinity form is capable of signal transduction. Cross-linking studies with 125I-NGF have shown that the high affinity receptor of rat PC12 cells forms an Mr 158,000 complex with NGF while the low affinity receptor forms an Mr 100,000 complex. Full length cDNA clones for both the human and rat NGF receptor genes have been produced and sequenced, revealing greater than 90% homology between the two species. NGF exhibits nerve growth stimulating activity and is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Further, NGF stimulates division and differentiation of sympathetic and embryonic sensory neurons. Mutations in the NGF gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF gene expression is associated with allergic rhinitis.
格式 :
冻干
应用w/稀释 :
Control: Assay-dependent, ELISA: Assay-dependent, Functional assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
别名 :
B nerve growth factor; beta ngf; beta-nerve growth factor; BetaNGF; beta-NGF; bNGF; b-NGF; HSAN5; MGC161426; MGC161428; nerve growth factor; nerve growth factor (beta polypeptide); nerve growth factor, beta; nerve growth factor, beta polypeptide; nerve growth factor, beta subunit; NGF; NGF b; NGF ß; Ngfb; NGFbeta; NGFß; ß nerve growth factor; ß NGF; ßNGF
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国