产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-13单克隆抗体(JES10-5A2)
目录 :
AHC0132
规格 :
500微克
价格 :
美国418
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
JES10-5A2
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪
更多信息或购买 :
文章摘录数: 5
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Koscher V, Milhe F, El Biaze M, Vervloet D, Magnan A. Variation of T-cell activation in allergic subjects during natural pollen exposure. Allergy. 2006;61:35-42 pubmed
|
| Boniface S, Koscher V, Mamessier E, El Biaze M, Dupuy P, Lorec A, et al. Assessment of T lymphocyte cytokine production in induced sputum from asthmatics: a flow cytometry study. Clin Exp Allergy. 2003;33:1238-43 pubmed
|
Vargas Hernandez A, Mace E, Zimmerman O, Zerbe C, Freeman A, Rosenzweig S, et al. Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations. J Allergy Clin Immunol. 2018;141:2142-2155.e5 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
IL-13单克隆抗体(JES10-5A2)
目录# :
AHC0132
规格 :
500微克
价格 :
美国418
克隆性 :
单克隆
纯度 :
纯化
宿主 :
大鼠
反应物种 :
人类
应用 :
ELISA: Assay Dependent, Flow Cytometry: Assay Dependent, Immunohistochemistry: Assay Dependent, Neutralization: Assay Dependent, Western Blot: Assay Dependent
物种 :
人类
克隆 :
JES10-5A2
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
免疫原 :
纯化重组人类IL-13
格式 :
液体
应用w/稀释 :
ELISA: Assay Dependent, Flow Cytometry: Assay Dependent, Immunohistochemistry: Assay Dependent, Neutralization: Assay Dependent, Western Blot: Assay Dependent
别名 :
ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; Interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
更多信息或购买 :
公司信息
赛默飞世尔