产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲单克隆抗体(68B2B3)
目录 :
AHC3912
规格 :
500微克
价格 :
美国375.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
68B2B3
反应物种 :
人类
应用 :
酶联免疫吸附测定, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 13
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:200
Freysdottir J, Zhang S, Tilakaratne W, Fortune F. Oral biopsies from patients with orofacial granulomatosis with histology resembling Crohn's disease have a prominent Th1 environment. Inflamm Bowel Dis. 2007;13:439-45 pubmed
  • 酶联免疫吸附测定; 人类
Janke M, Witsch E, Mages H, Hutloff A, Kroczek R. Eminent role of ICOS costimulation for T cells interacting with plasmacytoid dendritic cells. Immunology. 2006;118:353-60 pubmed
  • 酶联免疫吸附测定; 人类; 8 ug/ml
Njemini R, Lambert M, Demanet C, Mets T. The effect of aging and inflammation on heat shock protein 27 in human monocytes and lymphocytes. Exp Gerontol. 2006;41:312-9 pubmed
  • 酶联免疫吸附测定; 人类; 图 4
Shen C, Maerten P, Geboes K, Van Assche G, Rutgeerts P, Ceuppens J. Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model. Clin Immunol. 2005;115:250-9 pubmed
  • 酶联免疫吸附测定; 人类; 图 4
Shen C, Assche G, Colpaert S, Maerten P, Geboes K, Rutgeerts P, et al. Adalimumab induces apoptosis of human monocytes: a comparative study with infliximab and etanercept. Aliment Pharmacol Ther. 2005;21:251-8 pubmed
  • 酶联免疫吸附测定; 人类; 图 1
Arredouani M, Kasran A, Vanoirbeek J, Berger F, Baumann H, Ceuppens J. Haptoglobin dampens endotoxin-induced inflammatory effects both in vitro and in vivo. Immunology. 2005;114:263-71 pubmed
  • 酶联免疫吸附测定; 人类
Vinogradov E, Paul C, Li J, Zhou Y, Lyle E, Tapping R, et al. The structure and biological characteristics of the Spirochaeta aurantia outer membrane glycolipid LGLB. Eur J Biochem. 2004;271:4685-95 pubmed
  • 酶联免疫吸附测定; 人类; 1 ug/ml
Soop M, Duxbury H, Agwunobi A, Gibson J, Hopkins S, Childs C, et al. Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans. Am J Physiol Endocrinol Metab. 2002;282:E1276-85 pubmed
  • 酶联免疫吸附测定; 人类
Kooijman R, Coppens A, Hooghe Peters E. Igf-I inhibits spontaneous apoptosis in human granulocytes. Endocrinology. 2002;143:1206-12 pubmed
  • 酶联免疫吸附测定; 人类; 图 1
Bullens D, Kasran A, Thielemans K, Bakkus M, Ceuppens J. CD40L-induced IL-12 production is further enhanced by the Th2 cytokines IL-4 and IL-13. Scand J Immunol. 2001;53:455-63 pubmed
  • 酶联免疫吸附测定; 人类; 图 2, 3
Bullens D, Rafiq K, Charitidou L, Peng X, Kasran A, Warmerdam P, et al. Effects of co-stimulation by CD58 on human T cell cytokine production: a selective cytokine pattern with induction of high IL-10 production. Int Immunol. 2001;13:181-91 pubmed
  • 免疫组化-冰冻切片; 人类; 1:200; 图 2
Shields D, Avgeropoulos N, Banik N, Tyor W. Acute multiple sclerosis characterized by extensive mononuclear phagocyte infiltration. Neurochem Res. 2000;25:1517-20 pubmed
  • 酶联免疫吸附测定; 人类; 图 1
Tapping R, Akashi S, Miyake K, Godowski P, Tobias P. Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides. J Immunol. 2000;165:5780-7 pubmed
产品信息
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲单克隆抗体(68B2B3)
目录# :
AHC3912
规格 :
500微克
价格 :
美国375.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA:依实验方法而定
物种 :
人类
克隆 :
68B2B3
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
免疫原 :
纯化重组人类肿瘤坏死因子甲
格式 :
液体
应用w/稀释 :
ELISA:依实验方法而定
别名 :
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国