产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IFN丙单克隆抗体(67F 12A8 L1), 生物素
目录 :
AHC4539
规格 :
100µg
价格 :
美国345
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
67F 12A8 L1
反应物种 :
人类, 黑猩猩
应用 :
酶联免疫吸附测定, 其他
更多信息或购买 :
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 其他; 人类; 表 1
Wu F, Wang L, Guo Q, Zhao M, Gu H, Xu H, et al. A Homogeneous Immunoassay Method for Detecting Interferon-Gamma in Patients with Latent Tuberculosis Infection. J Microbiol Biotechnol. 2016;26:588-95 pubmed 出版商
  • 酶联免疫吸附测定; 黑猩猩; 图 3
Daubersies P, Ollomo B, Sauzet J, Brahimi K, Perlaza B, Eling W, et al. Genetic immunisation by liver stage antigen 3 protects chimpanzees against malaria despite low immune responses. PLoS ONE. 2008;3:e2659 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 图 3
Takeda K, Suzuki T, Shimada S, Shida K, Nanno M, Okumura K. Interleukin-12 is involved in the enhancement of human natural killer cell activity by Lactobacillus casei Shirota. Clin Exp Immunol. 2006;146:109-15 pubmed
  • 酶联免疫吸附测定; 人类
Gorski K, Waller E, Bjornton Severson J, Hanten J, Riter C, Kieper W, et al. Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists. Int Immunol. 2006;18:1115-26 pubmed
  • 酶联免疫吸附测定; 人类; 1:1000
Njemini R, Lambert M, Demanet C, Mets T. The effect of aging and inflammation on heat shock protein 27 in human monocytes and lymphocytes. Exp Gerontol. 2006;41:312-9 pubmed
  • 酶联免疫吸附测定; 人类
Haddeland U, Sletten G, Brandtzaeg P, Nakstad B. Impaired interleukin (IL)-4-associated generation of CCR4-expressing T cells in neonates with hereditary allergy risk. Clin Exp Immunol. 2005;139:314-22 pubmed
  • 酶联免疫吸附测定; 人类
Temmerman S, Pethe K, Parra M, Alonso S, Rouanet C, Pickett T, et al. Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin. Nat Med. 2004;10:935-41 pubmed
  • 酶联免疫吸附测定; 人类
Singh S, Soe S, Mejia J, Roussilhon C, Theisen M, Corradin G, et al. Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design. J Infect Dis. 2004;190:1010-8 pubmed
  • 酶联免疫吸附测定; 人类; 0.2 ug/ml; 表 1
Kooijman R, Coppens A. Insulin-like growth factor-I stimulates IL-10 production in human T cells. J Leukoc Biol. 2004;76:862-7 pubmed
  • 酶联免疫吸附测定; 人类; 0.5 ug/ml; 图 1
Stewart S, Vidali M, Day C, Albano E, Jones D. Oxidative stress as a trigger for cellular immune responses in patients with alcoholic liver disease. Hepatology. 2004;39:197-203 pubmed
  • 酶联免疫吸附测定; 人类; 图 4
Mascart F, Verscheure V, Malfroot A, Hainaut M, Pierard D, Temerman S, et al. Bordetella pertussis infection in 2-month-old infants promotes type 1 T cell responses. J Immunol. 2003;170:1504-9 pubmed
  • 酶联免疫吸附测定; 人类; 图 2, 3
Bullens D, Rafiq K, Charitidou L, Peng X, Kasran A, Warmerdam P, et al. Effects of co-stimulation by CD58 on human T cell cytokine production: a selective cytokine pattern with induction of high IL-10 production. Int Immunol. 2001;13:181-91 pubmed
  • 酶联免疫吸附测定; 人类
Braun M, He J, Wu C, Kelsall B. Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor beta1 and beta2 chain expression. J Exp Med. 1999;189:541-52 pubmed
Gordón Alonso M, Hirsch T, Wildmann C, van der Bruggen P. Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration. Nat Commun. 2017;8:793 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
IFN丙单克隆抗体(67F 12A8 L1), 生物素
目录# :
AHC4539
规格 :
100µg
价格 :
美国345
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA:依实验方法而定
物种 :
人类
克隆 :
67F 12A8 L1
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines. Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. IFN gamma gene mutations are associated with aplastic anemia.
免疫原 :
重组人类干扰素丙
格式 :
液体
应用w/稀释 :
ELISA:依实验方法而定
别名 :
IFN丙, IFN-y, 干扰素y, IFNG
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国