产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
AKT1单克隆抗体(9Q7)
目录 :
AHO1112
规格 :
100微克
价格 :
美国500
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
9Q7
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 s1a
  • 免疫印迹; 小鼠; 图 2c
Michael J, Wurtzel J, Goldfinger L. Regulation of H-Ras-driven MAPK signaling, transformation and tumorigenesis, but not PI3K signaling and tumor progression, by plasma membrane microdomains. Oncogenesis. 2016;5:e228 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s7
Nim S, Jeon J, Corbi Verge C, Seo M, Ivarsson Y, Moffat J, et al. Pooled screening for antiproliferative inhibitors of protein-protein interactions. Nat Chem Biol. 2016;12:275-81 pubmed 出版商
Cuellar Vite L, Weber Bonk K, Abdul Karim F, Booth C, Keri R. Focal Adhesion Kinase Provides a Collateral Vulnerability That Can Be Leveraged to Improve mTORC1 Inhibitor Efficacy. Cancers (Basel). 2022;14: pubmed 出版商
Shi L, Zhu W, Huang Y, Zhuo L, Wang S, Chen S, et al. Cancer-associated fibroblast-derived exosomal microRNA-20a suppresses the PTEN/PI3K-AKT pathway to promote the progression and chemoresistance of non-small cell lung cancer. Clin Transl Med. 2022;12:e989 pubmed 出版商
Duan S, Moro L, Qu R, Simoneschi D, Cho H, Jiang S, et al. Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis. Cell Rep. 2021;37:109870 pubmed 出版商
Rajendran N, Houreld N, Abrahamse H. In Vitro Wound Healing Potential of Photobiomodulation Is Possibly Mediated by Its Stimulatory Effect on AKT Expression in Adipose-Derived Stem Cells. Oxid Med Cell Longev. 2021;2021:6664627 pubmed 出版商
Gilmore J, Sardiu M, Groppe B, Thornton J, Liu X, Dayebgadoh G, et al. WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage. PLoS ONE. 2016;11:e0155492 pubmed 出版商
Banks C, Boanca G, Lee Z, Florens L, Washburn M. Proteins interacting with cloning scars: a source of false positive protein-protein interactions. Sci Rep. 2015;5:8530 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
AKT1单克隆抗体(9Q7)
目录# :
AHO1112
规格 :
100微克
价格 :
美国500
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:1000
物种 :
人类, 小鼠, 大鼠
克隆 :
9Q7
抗体亚型 :
IgG3, kappa
储存 :
-20°C
描述 :
AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
免疫原 :
重组人类AKT1蛋白
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:1000
别名 :
Akt; Akt kinase; AKT serine/threonine kinase 1; AKT/PKB; AKT1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006 gene product from transcript CG4006-RE; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dakt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel CG4006; Dmel_CG4006; DPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; p-Akt; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; Protein kinase B; protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; Rac; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; serine/threonine protein kinase; serine-threonine protein kinase; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国