产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-6受体单克隆抗体(B-N12)
目录 :
AHR0961
规格 :
100微克
价格 :
美国456.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B-N12
反应物种 :
人类
应用 :
酶联免疫吸附测定, 流式细胞仪
更多信息或购买 :
文章摘录数: 2
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Cervello M, Notarbartolo M, Landino M, Cusimano A, Virruso L, Montalto G, et al. Downregulation of wild-type beta-catenin expression by interleukin 6 in human hepatocarcinoma HepG2 cells: a possible role in the growth-regulatory effects of the cytokine?. Eur J Cancer. 2001;37:512-9 pubmed
|
| Bank U, Reinhold D, Schneemilch C, Kunz D, Synowitz H, Ansorge S. Selective proteolytic cleavage of IL-2 receptor and IL-6 receptor ligand binding chains by neutrophil-derived serine proteases at foci of inflammation. J Interferon Cytokine Res. 1999;19:1277-87 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
IL-6受体单克隆抗体(B-N12)
目录# :
AHR0961
规格 :
100微克
价格 :
美国456.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: Assay-dependent, Flow Cytometry: Assay-dependent
物种 :
人类
克隆 :
B-N12
抗体亚型 :
IgG1, kappa
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
免疫原 :
CHO cells transfected with cDNA produced from the gp80 IL-6 receptor mRNA.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Flow Cytometry: Assay-dependent
别名 :
CD126;CD126抗原;gp80;IL-6受体;白细胞介素-6受体甲;IL-6受体甲链;IL-6受体亚单位甲;IL6Q;IL6R;IL-6R;IL-6R 1;IL-6R亚单位甲;IL6R1;IL-6R;Il6ra;IL-6RA;IL-6R;IL6RQ;ILN;白细胞介素;白细胞介素6受体;白细胞介素6受体, 甲;白细胞介素6受体亚单位甲;膜糖蛋白80;MGC104991
更多信息或购买 :
公司信息
赛默飞世尔