产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IFN丙单克隆抗体(DB-1(DB1))
目录 :
ARC4033
规格 :
1毫克
价格 :
399.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DB-1(DB1)
反应物种 :
小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 29
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
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| Hoentjen F, Tonkonogy S, Liu B, Sartor R, Taurog J, Dieleman L. Adoptive transfer of nontransgenic mesenteric lymph node cells induces colitis in athymic HLA-B27 transgenic nude rats. Clin Exp Immunol. 2006;143:474-83 pubmed
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| Al Qaoud K, Abdel Hafez S. Humoral and cytokine response during protection of mice against secondary hydatidosis caused by Echinococcus granulosus. Parasitol Res. 2005;98:54-60 pubmed
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| Hoentjen F, Welling G, Harmsen H, Zhang X, Snart J, Tannock G, et al. Reduction of colitis by prebiotics in HLA-B27 transgenic rats is associated with microflora changes and immunomodulation. Inflamm Bowel Dis. 2005;11:977-85 pubmed
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| Qian B, Tonkonogy S, Hoentjen F, Dieleman L, Sartor R. Dysregulated luminal bacterial antigen-specific T-cell responses and antigen-presenting cell function in HLA-B27 transgenic rats with chronic colitis. Immunology. 2005;116:112-21 pubmed
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| Janelidze S, Enell K, Visse E, Darabi A, Salford L, Siesjo P. Activation of purified allogeneic CD4(+) T cells by rat bone marrow-derived dendritic cells induces concurrent secretion of IFN-gamma, IL-4, and IL-10. Immunol Lett. 2005;101:193-201 pubmed
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| Moalem G, Xu K, Yu L. T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats. Neuroscience. 2004;129:767-77 pubmed
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| Todd D, Forsberg E, Greiner D, Mordes J, Rossini A, Bortell R. Deficiencies in gut NK cell number and function precede diabetes onset in BB rats. J Immunol. 2004;172:5356-62 pubmed
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| Cabarrocas J, Piaggio E, Zappulla J, Desbois S, Mars L, Lassmann H, et al. A transgenic mouse model for T-cell ignorance of a glial autoantigen. J Autoimmun. 2004;22:179-89 pubmed
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| Dieleman L, Hoentjen F, Qian B, Sprengers D, Tjwa E, Torres M, et al. Reduced ratio of protective versus proinflammatory cytokine responses to commensal bacteria in HLA-B27 transgenic rats. Clin Exp Immunol. 2004;136:30-9 pubmed
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| Chakir H, Wang H, Lefebvre D, Webb J, Scott F. T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3. J Immunol Methods. 2003;278:157-69 pubmed
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| Archin N, Atherton S. Infiltration of T-lymphocytes in the brain after anterior chamber inoculation of a neurovirulent and neuroinvasive strain of HSV-1. J Neuroimmunol. 2002;130:117-27 pubmed
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| Sorkness R, Castleman W, Mikus L, Mosser A, Lemanske R. Chronic postbronchiolitis airway instability induced with anti-IFN-gamma antibody in F344 rats. Pediatr Res. 2002;52:382-6 pubmed
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| Hylkema M, Timens W, Luinge M, Van Der Werf N, Hoekstra M. The effect of bacillus Calmette-Guérin immunization depends on the genetic predisposition to Th2-type responsiveness. Am J Respir Cell Mol Biol. 2002;27:244-9 pubmed
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| Uehara K, Ichida T, Sugahara S, Ishikawa T, Yamagiwa S, Yoshida Y, et al. Systemic administration of liposome-encapsulated OK-432 prolongs the survival of rats with hepatocellular carcinoma through the induction of IFN-gamma-producing hepatic lymphocytes. J Gastroenterol Hepatol. 2002;17:81-90 pubmed
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| Todd D, Greiner D, Rossini A, Mordes J, Bortell R. An atypical population of NK cells that spontaneously secrete IFN-gamma and IL-4 is present in the intraepithelial lymphoid compartment of the rat. J Immunol. 2001;167:3600-9 pubmed
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| Liva S, Voskuhl R. Testosterone acts directly on CD4+ T lymphocytes to increase IL-10 production. J Immunol. 2001;167:2060-7 pubmed
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| Caraher E, Parenteau M, Gruber H, Scott F. Flow cytometric analysis of intracellular IFN-gamma, IL-4 and IL-10 in CD3(+)4(+) T-cells from rat spleen. J Immunol Methods. 2000;244:29-40 pubmed
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| Lin Y, Soares M, Sato K, Csizmadia E, Robson S, Smith N, et al. Long-term survival of hamster hearts in presensitized rats. J Immunol. 2000;164:4883-92 pubmed
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| Kawai T, Seki M, Hiromatsu K, Eastcott J, Watts G, Sugai M, et al. Selective diapedesis of Th1 cells induced by endothelial cell RANTES. J Immunol. 1999;163:3269-78 pubmed
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| Cetre C, Pierrot C, Cocude C, Lafitte S, Capron A, Capron M, et al. Profiles of Th1 and Th2 cytokines after primary and secondary infection by Schistosoma mansoni in the semipermissive rat host. Infect Immun. 1999;67:2713-9 pubmed
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| Lin Y, Soares M, Sato K, Takigami K, Csizmadia E, Anrather J, et al. Rejection of cardiac xenografts by CD4+ or CD8+ T cells. J Immunol. 1999;162:1206-14 pubmed
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| Miyatake T, Koyamada N, Hancock W, Soares M, Bach F. Survival of accommodated cardiac xenografts upon retransplantation into cyclosporine-treated recipients. Transplantation. 1998;65:1563-9 pubmed
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| Shibata Y, Metzger W, Myrvik Q. Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan: mannose receptor-mediated phagocytosis initiates IL-12 production. J Immunol. 1997;159:2462-7 pubmed
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| Shibata Y, Foster L, Metzger W, Myrvik Q. Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in mice. Infect Immun. 1997;65:1734-41 pubmed
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| Früh R, Blum B, Mossmann H, Domdey H, von Specht B. TH1 cells trigger tumor necrosis factor alpha-mediated hypersensitivity to Pseudomonas aeruginosa after adoptive transfer into SCID mice. Infect Immun. 1995;63:1107-12 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IFN丙单克隆抗体(DB-1(DB1))
目录# :
ARC4033
规格 :
1毫克
价格(美元) :
399.00美元
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
小鼠, 大鼠
应用 :
ELISA: 10 µg/mL, Immunocytochemistry: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Neutralization: Assay Dependent, Western Blot: Assay Dependent
物种 :
小鼠, 大鼠
克隆 :
DB-1(DB1)
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines. Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. IFN gamma gene mutations are associated with aplastic anemia.
免疫原 :
大鼠/小鼠IFN丙
格式 :
冻干
应用w/稀释 :
ELISA: 10 µg/mL, Immunocytochemistry: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Neutralization: Assay Dependent, Western Blot: Assay Dependent
别名 :
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; Ifg; IFI; IFN gamma; IFN ?; IFNG; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g
更多信息或购买 :
公司信息
赛默飞世尔