产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD44var (v6) Monoclonal Antibody (VFF-18), eBioscience
目录 :
BMS125
规格 :
100微克
价格 :
美国231
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
VFF-18
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 1:100; 图 1
Santhana Kumar K, Tripolitsioti D, Ma M, Grählert J, Egli K, Fiaschetti G, et al. The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma. Springerplus. 2015;4:19 pubmed 出版商
Goldstein L, Mansutti M, Levy C, Chang J, Henry S, Fernández Pérez I, et al. A randomized, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as front-line therapy for metastatic triple-negative breast cancer (fRida). Breast Cancer Res Treat. 2021;190:265-275 pubmed 出版商
Jowett G, Norman M, Yu T, Rosell Arévalo P, Hoogland D, Lust S, et al. ILC1 drive intestinal epithelial and matrix remodelling. Nat Mater. 2021;20:250-259 pubmed 出版商
Huang L, Bockorny B, Paul I, Akshinthala D, Frappart P, Gandarilla O, et al. PDX-derived organoids model in vivo drug response and secrete biomarkers. JCI Insight. 2020;5: pubmed 出版商
Loh T, Moon H, Cho S, Jang H, Liu Y, Tai H, et al. CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer. Oncol Rep. 2015;34:1231-8 pubmed 出版商
Casucci M, Nicolis Di Robilant B, Falcone L, Camisa B, Norelli M, Genovese P, et al. CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma. Blood. 2013;122:3461-72 pubmed 出版商
Vermeulen J, van der Wall E, Witkamp A, van Diest P. Analysis of expression of membrane-bound tumor markers in ductal carcinoma in situ of the breast: paving the way for molecular imaging. Cell Oncol (Dordr). 2013;36:333-40 pubmed 出版商
Zeilstra J, Joosten S, van Andel H, Tolg C, Berns A, Snoek M, et al. Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling. Oncogene. 2014;33:665-70 pubmed 出版商
Vermeulen J, van Brussel A, Adams A, Mali W, van der Wall E, van Diest P, et al. Near-infrared fluorescence molecular imaging of ductal carcinoma in situ with CD44v6-specific antibodies in mice: a preclinical study. Mol Imaging Biol. 2013;15:290-8 pubmed 出版商
Girbl T, Hinterseer E, Grössinger E, Asslaber D, Oberascher K, Weiss L, et al. CD40-mediated activation of chronic lymphocytic leukemia cells promotes their CD44-dependent adhesion to hyaluronan and restricts CCL21-induced motility. Cancer Res. 2013;73:561-70 pubmed 出版商
Vermeulen J, van Brussel A, van der Groep P, Morsink F, Bult P, van der Wall E, et al. Immunophenotyping invasive breast cancer: paving the road for molecular imaging. BMC Cancer. 2012;12:240 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD44var (v6) Monoclonal Antibody (VFF-18), eBioscience
目录# :
BMS125
规格 :
100微克
价格 :
美国231
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: Assay-Dependent
物种 :
人类
克隆 :
VFF-18
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
免疫原 :
Rec. Human CD44var (v6)
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: Assay-Dependent
别名 :
AL133330.1; AU023126; AW121933; AW146109; CD44; CD44 antigen; CD44 molecule (Indian blood group); CD44 splice variant; CD44 V6; CD44 var; CD44 variant; CD44v6; CD44var (v6); CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCHI; HUTCH-I; Hyaluronate receptor; IN; LHR; Ly-24; Lymphocyte antigen 24; MC56; MDU2; MDU3; MGC10468; MIC4; MUTCH-I; PGP I; Pgp1; Pgp-1; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; soluble CD44
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国