产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
纤连蛋白单克隆抗体(A32)
目录 :
CSI 005-32-02
规格 :
200微升
价格 :
美国796
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A32
反应物种 :
人类,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 3
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 人类; 1:100; 图 3a
Degendorfer G, Chuang C, Kawasaki H, Hammer A, Malle E, Yamakura F, et al. Peroxynitrite-mediated oxidation of plasma fibronectin. Free Radic Biol Med. 2016;97:602-615 pubmed 出版商
  • 免疫组化; 人类; 1:200
  • 酶联免疫吸附测定; 人类
Hubbard B, Buczek Thomas J, Nugent M, Smith M. Heparin-dependent regulation of fibronectin matrix conformation. Matrix Biol. 2014;34:124-31 pubmed 出版商
Gamon L, Dieterich S, Ignasiak M, Schrameyer V, Davies M. Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase. Redox Biol. 2020;28:101331 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
纤连蛋白单克隆抗体(A32)
目录# :
CSI 005-32-02
规格 :
200微升
价格 :
美国796
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
牛, 人类
应用 :
ELISA: 1:4,000, Immunohistochemistry (Frozen): Assay dependent, Immunoprecipitation: Assay dependent, Western Blot: 1:100
物种 :
牛, 人类
克隆 :
A32
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark
描述 :
Fibronectin is a disulfide-bonded dimer with a molecular weight range of 230-250 kDa. In the extracellular matrix of several connective tissues and vessels, fibronectin is present as an insoluble protein that is extensively cross-linked by interchain disulfide bonds forming high molecular mass polymers. Fibronectin is most abundant during embryonic development and tissue remodeling. Fibronectin is also present at high concentrations as a soluble plasma protein. Fibronectin is organized as a linear series of repeating modules which form domains for interaction with fibronectin itself, other matrix components (e.g. collagen and heparin) and receptors on cells (e.g. integrins). Fibronectin is present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. Fibronectin has been implicated in carcinoma development in lung cancer. Further, Fibronectin expression is increased especially in non-small cell lung carcinoma. The adhesion of lung carcinoma cells to Fibronectin enhances tumorgenecity and confers resistance to apoptosis induced by standard chemotherapeutic agents. The gene encoding Fibronectin has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some Fibronectin variants has not been determined.
免疫原 :
Bovine corneal endothelial cells.
格式 :
液体
应用w/稀释 :
ELISA: 1:4,000, Immunohistochemistry (Frozen): Assay dependent, Immunoprecipitation: Assay dependent, Western Blot: 1:100
别名 :
Anastellin; CIG; Cold-insoluble globulin; cumulus cell-specific fibronectin 1 transcript; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; E330027I09; ED-B; embryo-specific fibronectin 1 transcript; ferritin L subunit; ferritin L-chain; FIBNEC; Fibronectin; fibronectin 1; fibronectin ED-A- region; fibronectin ED-B+ region; fibronectin variable region; FINC; Fn; FN1; fn-1; FNZ; GFND; GFND2; LETS; LOW QUALITY PROTEIN: fibronectin; migration-stimulating factor; MSF; Ugl-Y1; Ugl-Y2; Ugl-Y3
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国