产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD103单克隆抗体(2E7), PE
目录 :
HMCD10304
规格 :
100微克
价格 :
美国261.00
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
PE
克隆名称 :
2E7
反应物种 :
人类, 小鼠
应用 :
免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 2
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| |
| Cerf Bensussan N, Begue B, Gagnon J, Meo T. The human intraepithelial lymphocyte marker HML-1 is an integrin consisting of a beta 7 subunit associated with a distinctive alpha chain. Eur J Immunol. 1992;22:273-7 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
CD103单克隆抗体(2E7), PE
目录# :
HMCD10304
规格 :
100微克
价格 :
美国261.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
亚美尼亚仓鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.1-0.2 µg / 1x10^6 cells
物种 :
小鼠
克隆 :
2E7
抗体亚型 :
IgG2
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD103 (ITGAE, Integrin alpha E) is molecule that is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells. In particular, CD103 includes a 150kDa alpha chain and a 120kDa beta chain. CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs. CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. CD103 is part of the integrin family which are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, CD103 protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. CD103 is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. Diseases associated with CD103 dysfunction include hairy cell leukemia and splenic marginal zone lymphoma.
免疫原 :
Mouse CD103. from C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL)
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.1-0.2 µg / 1x10^6 cells
别名 :
A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen
更多信息或购买 :
公司信息
赛默飞世尔