产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CTLA-4单克隆抗体(1B8), 异硫氰酸荧光素
目录 :
HMCD15201
规格 :
500微克
价格 :
美国427.00
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
1B8
反应物种 :
小鼠
应用 :
酶联免疫吸附测定, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 4
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Leach D, Krummel M, Allison J. Enhancement of antitumor immunity by CTLA-4 blockade. Science. 1996;271:1734-6 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
CTLA-4单克隆抗体(1B8), 异硫氰酸荧光素
目录# :
HMCD15201
规格 :
500微克
价格 :
美国427.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
亚美尼亚仓鼠
反应物种 :
小鼠
应用 :
ELISA: 3 µg/10^6 cells, Flow Cytometry: 0.1-0.2 µg / 1x10^6 cells
物种 :
小鼠
克隆 :
1B8
抗体亚型 :
IgG1
储存 :
4° C, store in dark
描述 :
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
免疫原 :
Mouse CD152 (CTLA-4). from Extracellular portion of murine CTLA-4 fused to a murine IgG2a
格式 :
液体
应用w/稀释 :
ELISA: 3 µg/10^6 cells, Flow Cytometry: 0.1-0.2 µg / 1x10^6 cells
别名 :
ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form
更多信息或购买 :
公司信息
赛默飞世尔