产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
ELISA/assay
产品名称 :
纤维生长因子2人类酶联免疫吸附试剂盒
目录 :
KHG0021
规格 :
96试验
价格 :
459.00美元
更多信息或购买 :
文章摘录数: 2
参考文献
DiGiacomo J, Godet I, Trautmann Rodriguez M, Gilkes D. Extracellular Matrix-Bound FGF2 Mediates Estrogen Receptor Signaling and Therapeutic Response in Breast Cancer. Mol Cancer Res. 2021;19:136-149 pubmed 出版商
Ali Z, Islam A, Sherrell P, Le Moine M, Lolas G, Syrigos K, et al. Adjustable delivery of pro-angiogenic FGF-2 by alginate:collagen microspheres. Biol Open. 2018;7: pubmed 出版商
产品信息
产品类型 :
酶联免疫吸附测定
目录号 :
KHG0021
类别 :
酶联免疫吸附试剂盒
靶标 :
纤维生长因子2
产品名称 :
纤维生长因子2人类酶联免疫吸附试剂盒
描述 :
FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.
同义词 :
Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin
价格(美元) :
459.00美元
规格 :
96试验
物种活性 :
人类
应用 :
酶联免疫吸附测定
储存 :
2-8°C
检测范围 :
15.6-1000 pg/mL
样品类型 :
Plasma, 50 µL Serum, 50 µL Supernatant, 50 µL
Assay Length :
1小时20分钟
提示 :
This product is for research use only.
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国