产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PRDX2单克隆抗体(1E8)
目录 :
LF-MA0144
规格 :
100微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1E8
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:2000; 图 5c
Yeung P, Lai A, Son H, Zhang X, Hwang O, Chung S, et al. Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson's disease. Neurobiol Aging. 2017;50:119-133 pubmed 出版商
Talwar D, Messens J, Dick T. A role for annexin A2 in scaffolding the peroxiredoxin 2-STAT3 redox relay complex. Nat Commun. 2020;11:4512 pubmed 出版商
Wang S, Chen Z, Zhu S, Lu H, Peng D, Soutto M, et al. PRDX2 protects against oxidative stress induced by H. pylori and promotes resistance to cisplatin in gastric cancer. Redox Biol. 2020;28:101319 pubmed 出版商
Kim M, Lee H, Lee S, Lee H, Huh J, Bae Y, et al. Peroxiredoxin 5 Inhibits Glutamate-Induced Neuronal Cell Death through the Regulation of Calcineurin-Dependent Mitochondrial Dynamics in HT22 Cells. Mol Cell Biol. 2019;39: pubmed 出版商
Liu S, Mahairaki V, Bai H, Ding Z, Li J, Witwer K, et al. Highly Purified Human Extracellular Vesicles Produced by Stem Cells Alleviate Aging Cellular Phenotypes of Senescent Human Cells. Stem Cells. 2019;37:779-790 pubmed 出版商
Lee E, Lee H. Peroxidase expression is decreased by palmitate in cultured podocytes but increased in podocytes of advanced diabetic nephropathy. J Cell Physiol. 2018;233:9060-9069 pubmed 出版商
Kim J, Park S, Kim B, Choe Y, Lee D. Insulin-stimulated lipid accumulation is inhibited by ROS-scavenging chemicals, but not by the Drp1 inhibitor Mdivi-1. PLoS ONE. 2017;12:e0185764 pubmed 出版商
Hintsala H, Soini Y, Haapasaari K, Karihtala P. Dysregulation of redox-state-regulating enzymes in melanocytic skin tumours and the surrounding microenvironment. Histopathology. 2015;67:348-57 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
PRDX2单克隆抗体(1E8)
目录# :
LF-MA0144
规格 :
100微升
价格 :
美国425.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
ELISA: Assay-dependent, Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
1E8
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
免疫原 :
重组人类蛋白纯化来自大肠杆菌
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 µg/mL
别名 :
AL022839; Band-8; Calpromotin; epididymis secretory sperm binding protein Li 2a; HEL-S-2a; HGNC:9353; MGC4104; Natural killer cell-enhancing factor B; NkefB; NKEF-B; peroxiredoxin 2; peroxiredoxin-2; Prdx2; protector protein; PRP; Prx II-1; PRX2; PRXII; PTX1; Tdpx1; TDX1; thiol specific antioxidant protein; thiol-specific antioxidant 1; thiol-specific antioxidant protein; thioredoxin dependent peroxide reductase 1; thioredoxin peroxidase 1; thioredoxin reductase; thioredoxin-dependent peroxide reductase 1; Torin; TPx; TPX1; TPx-B; TR; Trx dependent peroxide reductase 1; TSA
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国