产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PRDX4多克隆抗体
目录 :
LF-PA0009
规格 :
100µL
价格 :
美国390
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 1
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 6f
Seo B, Min K, Woo S, Choe M, Choi K, Lee Y, et al. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Antioxid Redox Signal. 2017;27:215-233 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
PRDX4多克隆抗体
目录# :
LF-PA0009
规格 :
100µL
价格 :
美国390
克隆性 :
多克隆
纯度 :
硫酸铵沉淀
宿主 :
反应物种 :
人类
应用 :
Immunohistochemistry (Paraffin): Assay Dependent, Western Blot: 1:2000
物种 :
人类
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
免疫原 :
Recombinant human fragment protein (without secretion leader sequence) purified from E.coli.
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): Assay Dependent, Western Blot: 1:2000
别名 :
Antioxidant enzyme AOE372; AOE372; AOE37-2; epididymis secretory sperm binding protein Li 97n; HEL-S-97n; peroxiredoxin 4; Peroxiredoxin IV; Peroxiredoxin-4; PRDX4; Prx 4; Prx IV; Prx4; PRX-4; Prx-IV; Rno2CysPrx04; thioredoxin peroxidase (antioxidant enzyme); Thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372; TRANK
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国