产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-10单克隆抗体(12G8), 生物素
目录 :
M011B
规格 :
250微克
价格 :
美国430.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
12G8
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 酶联免疫吸附测定; 人类; 1:1,000
Gregori S, Roncarolo M, Bacchetta R. Methods for in vitro generation of human type 1 regulatory T cells. Methods Mol Biol. 2011;677:31-46 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Bacchetta R, Gregori S, Serafini G, Sartirana C, Schulz U, Zino E, et al. Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy. Haematologica. 2010;95:2134-43 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Eksioglu E, Bess J, Zhu H, Xu Y, Dong H, Elyar J, et al. Hepatitis C virus modulates human monocyte-derived dendritic cells. J Viral Hepat. 2010;17:757-69 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Serafini G, Andreani M, Testi M, Battarra M, Bontadini A, Biral E, et al. Type 1 regulatory T cells are associated with persistent split erythroid/lymphoid chimerism after allogeneic hematopoietic stem cell transplantation for thalassemia. Haematologica. 2009;94:1415-26 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Lee T, Leu S, Huang J, Song Y, Jhou R, Tang S, et al. Anti-ribosomal phosphoprotein autoantibody triggers interleukin-10 overproduction via phosphatidylinositol 3-kinase-dependent signalling pathways in lipopolysaccharide-activated macrophages. Immunology. 2009;127:91-102 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Della Bella S, Riva A, Tanzi E, Nicola S, Amendola A, Vecchi L, et al. Hepatitis C virus-specific reactivity of CD4+-lymphocytes in children born from HCV-infected women. J Hepatol. 2005;43:394-402 pubmed
  • 酶联免疫吸附测定; 人类; 图 1
Suwa T, Hogg J, Vincent R, Mukae H, Fujii T, van Eeden S. Ambient air particulates stimulate alveolar macrophages of smokers to promote differentiation of myeloid precursor cells. Exp Lung Res. 2002;28:1-18 pubmed
Schotte H, Schluter B, Willeke P, Mickholz E, Schorat M, Domschke W, et al. Long-term treatment with etanercept significantly reduces the number of proinflammatory cytokine-secreting peripheral blood mononuclear cells in patients with rheumatoid arthritis. Rheumatology (Oxford). 2004;43:960-4 pubmed
Della Bella S, Gennaro M, Vaccari M, Ferraris C, Nicola S, Riva A, et al. Altered maturation of peripheral blood dendritic cells in patients with breast cancer. Br J Cancer. 2003;89:1463-72 pubmed
Meloni F, Cascina A, Paschetto E, Marone Bianco A, Morosini M, Pellegrini C, et al. Monocyte chemoattractant protein-1 levels in bronchoalveolar lavage fluid of lung-transplanted patients treated with tacrolimus as rescue treatment for refractory acute rejection. Transplant Proc. 2003;35:1523-6 pubmed
Solomon S, Masilamani M, Mohanty S, Schwab J, Boneberg E, Illges H. Generation of three-dimensional pannus-like tissues in vitro from single cell suspensions of synovial fluid cells from arthritis patients. Rheumatol Int. 2004;24:71-6 pubmed
Loffreda S, Muratori P, Muratori L, Mele L, Bianchi F, Lenzi M. Enhanced monocyte Th1 cytokine production in HCV-infected cryoglobulinemic patients. J Hepatol. 2003;38:230-6 pubmed
McDowell M, Marovich M, Lira R, Braun M, Sacks D. Leishmania priming of human dendritic cells for CD40 ligand-induced interleukin-12p70 secretion is strain and species dependent. Infect Immun. 2002;70:3994-4001 pubmed
Zarzaur B, Wu Y, Fukatsu K, Johnson C, Kudsk K. The neuropeptide bombesin improves IgA-mediated mucosal immunity with preservation of gut interleukin-4 in total parenteral nutrition-fed mice. Surgery. 2002;131:59-65 pubmed
Boneberg E, Hartung T. Mistletoe lectin-1 increases tumor necrosis factor-alpha release in lipopolysaccharide-stimulated whole blood via inhibition of interleukin-10 production. J Pharmacol Exp Ther. 2001;298:996-1000 pubmed
Whittaker D, Bahjat K, Moldawer L, Clare Salzler M. Autoregulation of human monocyte-derived dendritic cell maturation and IL-12 production by cyclooxygenase-2-mediated prostanoid production. J Immunol. 2000;165:4298-304 pubmed
Chung S, Yoshida E, Cattral M, Hu Y, Gorczynski R. Donor-specific stimulation of peripheral blood mononuclear cells from recipients of orthotopic liver transplants is associated, in the absence of rejection, with type-2 cytokine production. Immunol Lett. 1998;63:91-6 pubmed
Anstey N, Weinberg J, Hassanali M, Mwaikambo E, Manyenga D, Misukonis M, et al. Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. J Exp Med. 1996;184:557-67 pubmed
Chomarat P, Rissoan M, Pin J, Banchereau J, Miossec P. Contribution of IL-1, CD14, and CD13 in the increased IL-6 production induced by in vitro monocyte-synoviocyte interactions. J Immunol. 1995;155:3645-52 pubmed
产品信息
产品类型 :
抗体
产品名称 :
IL-10单克隆抗体(12G8), 生物素
目录# :
M011B
规格 :
250微克
价格 :
美国430.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
人类
应用 :
ELISA: Assay-dependent, Western Blot: 1:1000
物种 :
人类
克隆 :
12G8
抗体亚型 :
IgG2a
储存 :
-20°C
描述 :
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
免疫原 :
Recombinant human IL-10 (COS cell-derived)
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Western Blot: 1:1000
别名 :
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国