产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GM-CSF单克隆抗体(1089)
目录 :
M501
规格 :
500微克
价格 :
美国428
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1089
反应物种 :
人类
应用 :
酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 11
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
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Tsunoda M, Litonjua A, Kuniak M, Weiss S, Satoh T, Guevarra L, et al. Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women. Int Arch Allergy Immunol. 2003;130:158-64 pubmed
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Kim M, Manoukian R, Yeh R, Silbiger S, Danilenko D, Scully S, et al. Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production. Blood. 2002;100:2330-40 pubmed
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Gao W, Wortis H, Pereira M. The Trypanosoma cruzi trans-sialidase is a T cell-independent B cell mitogen and an inducer of non-specific Ig secretion. Int Immunol. 2002;14:299-308 pubmed
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Lee C, Kim J, Kim K, Han S. A mouse thymic stromal cell line producing macrophage-colony stimulating factor and interleukin-6. Arch Pharm Res. 2000;23:252-6 pubmed
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Lees C, Apostolopoulos V, Acres B, Ong C, Popovski V, McKenzie I. The effect of T1 and T2 cytokines on the cytotoxic T cell response to mannan-MUC1. Cancer Immunol Immunother. 2000;48:644-52 pubmed
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Cavallo F, Signorelli P, Giovarelli M, Musiani P, Modesti A, Brunda M, et al. Antitumor efficacy of adenocarcinoma cells engineered to produce interleukin 12 (IL-12) or other cytokines compared with exogenous IL-12. J Natl Cancer Inst. 1997;89:1049-58 pubmed
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Rennert P, Furlong K, Jellis C, Greenfield E, Freeman G, Ueda Y, et al. The IgV domain of human B7-2 (CD86) is sufficient to co-stimulate T lymphocytes and induce cytokine secretion. Int Immunol. 1997;9:805-13 pubmed
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Vitkovic L, Chatham J, da Cunha A. Distinct expressions of three cytokines by IL-1-stimulated astrocytes in vitro and in AIDS brain. Brain Behav Immun. 1995;9:378-88 pubmed
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Gabriele L, Kaido T, Woodrow D, Moss J, Ferrantini M, Proletti E, et al. Local and systemic response of mice to interferon-alpha 1-transfected Friend leukemia cells. Am J Pathol. 1995;147:445-60 pubmed
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Kanakura Y, Cannistra S, Brown C, Nakamura M, Seelig G, Prosise W, et al. Identification of functionally distinct domains of human granulocyte-macrophage colony-stimulating factor using monoclonal antibodies. Blood. 1991;77:1033-43 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
GM-CSF单克隆抗体(1089)
目录# :
M501
规格 :
500微克
定价 :
美国428
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA:依实验方法而定
物种 :
人类
克隆 :
1089
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).
免疫原 :
Glycosylated, CHO-derived recombinant human GM-CSF
格式 :
液体
应用w/稀释 :
ELISA:依实验方法而定
别名 :
colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
更多信息或购买 :
公司信息
赛默飞世尔