产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GM-CSF单克隆抗体(1089), 生物素
目录 :
M501B
规格 :
250微克
价格 :
美国428
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
1089
反应物种 :
人类
应用 :
酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 3
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| |
Cakouros D, Cockerill P, Bert A, Mital R, Roberts D, Shannon M. A NF-kappa B/Sp1 region is essential for chromatin remodeling and correct transcription of a human granulocyte-macrophage colony-stimulating factor transgene. J Immunol. 2001;167:302-10 pubmed
| |
Kanakura Y, Cannistra S, Brown C, Nakamura M, Seelig G, Prosise W, et al. Identification of functionally distinct domains of human granulocyte-macrophage colony-stimulating factor using monoclonal antibodies. Blood. 1991;77:1033-43 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
GM-CSF单克隆抗体(1089), 生物素
目录# :
M501B
规格 :
250微克
定价 :
美国428
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA:依实验方法而定
物种 :
人类
克隆 :
1089
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).
免疫原 :
Glycosylated, CHO-derived recombinant human GM-CSF
格式 :
液体
应用w/稀释 :
ELISA:依实验方法而定
别名 :
colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
更多信息或购买 :
公司信息
赛默飞世尔