产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-6单克隆抗体(7IL6), 生物素
目录 :
M621B
规格 :
250微克
价格 :
美国489
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
7IL6
反应物种 :
人类, 小鼠, pigs
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 20
| 出版应用/物种/样本/稀释 | 参考文献 |
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| Saffar A, Alphonse M, Shan L, Hayglass K, Simons F, Gounni A. IgE modulates neutrophil survival in asthma: role of mitochondrial pathway. J Immunol. 2007;178:2535-41 pubmed
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| Urbanowska T, Mangialaio S, Zickler C, Cheevapruk S, Hasler P, Regenass S, et al. Protein microarray platform for the multiplex analysis of biomarkers in human sera. J Immunol Methods. 2006;316:1-7 pubmed
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| Matsumoto S, Hara T, Hori T, Mitsuyama K, Nagaoka M, Tomiyasu N, et al. Probiotic Lactobacillus-induced improvement in murine chronic inflammatory bowel disease is associated with the down-regulation of pro-inflammatory cytokines in lamina propria mononuclear cells. Clin Exp Immunol. 2005;140:417-26 pubmed
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| Suwa T, Hogg J, Vincent R, Mukae H, Fujii T, van Eeden S. Ambient air particulates stimulate alveolar macrophages of smokers to promote differentiation of myeloid precursor cells. Exp Lung Res. 2002;28:1-18 pubmed
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Siebert J, Hamann L, Verolet C, Gameiro C, Grillet S, Siegrist C, et al. Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children. Front Immunol. 2018;9:1780 pubmed 出版商
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Schotte H, Schluter B, Willeke P, Mickholz E, Schorat M, Domschke W, et al. Long-term treatment with etanercept significantly reduces the number of proinflammatory cytokine-secreting peripheral blood mononuclear cells in patients with rheumatoid arthritis. Rheumatology (Oxford). 2004;43:960-4 pubmed
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Hsiao Y, Liao K, Hung S, Chu R. Tumor-infiltrating lymphocyte secretion of IL-6 antagonizes tumor-derived TGF-beta 1 and restores the lymphokine-activated killing activity. J Immunol. 2004;172:1508-14 pubmed
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Reinartz S, Hombach A, Köhler S, Schlebusch H, Wallwiener D, Abken H, et al. Interleukin-6 fused to an anti-idiotype antibody in a vaccine increases the specific humoral immune response against CA125+ (MUC-16) ovarian cancer. Cancer Res. 2003;63:3234-40 pubmed
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Tsunoda M, Litonjua A, Kuniak M, Weiss S, Satoh T, Guevarra L, et al. Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women. Int Arch Allergy Immunol. 2003;130:158-64 pubmed
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Miner J, Tyree C, Hu J, Berger E, Marschke K, Nakane M, et al. A nonsteroidal glucocorticoid receptor antagonist. Mol Endocrinol. 2003;17:117-27 pubmed
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King C, Marshall J, Alshurafa H, Anderson R. Release of vasoactive cytokines by antibody-enhanced dengue virus infection of a human mast cell/basophil line. J Virol. 2000;74:7146-50 pubmed
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Marth T, Kelsall B. Regulation of interleukin-12 by complement receptor 3 signaling. J Exp Med. 1997;185:1987-95 pubmed
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May L, Patel K, Garcia D, Ndubuisi M, Ferrone S, Mittelman A, et al. Sustained high levels of circulating chaperoned interleukin-6 after active specific cancer immunotherapy. Blood. 1994;84:1887-95 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IL-6单克隆抗体(7IL6), 生物素
目录# :
M621B
规格 :
250微克
定价 :
美国489
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类
克隆 :
7IL6
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes. In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.
免疫原 :
重组人类IL-6
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Western Blot: Assay-dependent
别名 :
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
更多信息或购买 :
公司信息
赛默飞世尔