产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IFN丙单克隆抗体(B133.5)
目录 :
M701
规格 :
500微克
价格 :
美国428
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B133.5
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪
更多信息或购买 :
文章摘录数: 83
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| Nowacki T, Kuerten S, Zhang W, Shive C, Kreher C, Boehm B, et al. Granzyme B production distinguishes recently activated CD8(+) memory cells from resting memory cells. Cell Immunol. 2007;247:36-48 pubmed
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| Chen X, O Donnell M, Luo Y. Dose-dependent synergy of Th1-stimulating cytokines on bacille Calmette-Guérin-induced interferon-gamma production by human mononuclear cells. Clin Exp Immunol. 2007;149:178-85 pubmed
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| Basu R, Roy S, Walden P. HLA class I-restricted T cell epitopes of the kinetoplastid membrane protein-11 presented by Leishmania donovani-infected human macrophages. J Infect Dis. 2007;195:1373-80 pubmed
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| Kitawaki T, Kadowaki N, Sugimoto N, Kambe N, Hori T, Miyachi Y, et al. IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells. Int Immunol. 2006;18:1789-99 pubmed
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| Alleva D, Maki R, Putnam A, Robinson J, Kipnes M, Dandona P, et al. Immunomodulation in type 1 diabetes by NBI-6024, an altered peptide ligand of the insulin B epitope. Scand J Immunol. 2006;63:59-69 pubmed
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| Nagarajan S, Selvaraj P. Human tumor membrane vesicles modified to express glycolipid-anchored IL-12 by protein transfer induce T cell proliferation in vitro: a potential approach for local delivery of cytokines during vaccination. Vaccine. 2006;24:2264-74 pubmed
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| Kleen T, Kadereit S, Fanning L, Jaroscak J, Fu P, Meyerson H, et al. Recipient-specific tolerance after HLA-mismatched umbilical cord blood stem cell transplantation. Transplantation. 2005;80:1316-22 pubmed
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| Kuekrek H, Schlingmann T, Valdez H, Boehm B, Pollard R, Mitsuyasu R, et al. Differential effect of interleukin-2 treatment on primary and secondary immunizations in HIV infected individuals. AIDS. 2005;19:1967-74 pubmed
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| Quast S, Zhang W, Shive C, Kovalovski D, Ott P, Herzog B, et al. IL-2 absorption affects IFN-gamma and IL-5, but not IL-4 producing memory T cells in double color cytokine ELISPOT assays. Cell Immunol. 2005;237:28-36 pubmed
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| Berner B, Tary Lehmann M, Yonkers N, Askari A, Lehmann P, Anthony D. Phenotypic and functional analysis of EBV-specific memory CD8 cells in SLE. Cell Immunol. 2005;235:29-38 pubmed
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| Lyke K, Burges R, Cissoko Y, Sangare L, Kone A, Dao M, et al. HLA-A2 supertype-restricted cell-mediated immunity by peripheral blood mononuclear cells derived from Malian children with severe or uncomplicated Plasmodium falciparum malaria and healthy controls. Infect Immun. 2005;73:5799-808 pubmed
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| Groh M, Maitra B, Szekely E, Koc O. Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells. Exp Hematol. 2005;33:928-34 pubmed
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| Della Bella S, Riva A, Tanzi E, Nicola S, Amendola A, Vecchi L, et al. Hepatitis C virus-specific reactivity of CD4+-lymphocytes in children born from HCV-infected women. J Hepatol. 2005;43:394-402 pubmed
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| Konur A, Schulz U, Eissner G, Andreesen R, Holler E. Interferon (IFN)-gamma is a main mediator of keratinocyte (HaCaT) apoptosis and contributes to autocrine IFN-gamma and tumour necrosis factor-alpha production. Br J Dermatol. 2005;152:1134-42 pubmed
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| Salerno Goncalves R, Wahid R, Sztein M. Immunization of volunteers with Salmonella enterica serovar Typhi strain Ty21a elicits the oligoclonal expansion of CD8+ T cells with predominant Vbeta repertoires. Infect Immun. 2005;73:3521-30 pubmed
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| Tambur A, Ben Ari Z, Herrera N, Klein T, Michowiz R, Mor E. Donor-specific hyporesponsiveness in ELISPOT assay is associated with early recurrence of hepatitis C in liver transplant recipients. Hum Immunol. 2005;66:21-7 pubmed
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| Meloni F, Cascina A, Paschetto E, Marone Bianco A, Morosini M, Pellegrini C, et al. Monocyte chemoattractant protein-1 levels in bronchoalveolar lavage fluid of lung-transplanted patients treated with tacrolimus as rescue treatment for refractory acute rejection. Transplant Proc. 2003;35:1523-6 pubmed
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Szmacinski H, Toshchakov V, Piao W, Lakowicz J. Imaging of Protein Secretion from a Single Cell Using Plasmonic Substrates. Bionanoscience. 2013;3:30-36 pubmed
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de Jong J, Stoop H, Gillis A, van Gurp R, van Drunen E, Beverloo H, et al. JKT-1 is not a human seminoma cell line. Int J Androl. 2007;30:350-65 pubmed
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Guthmann M, Bitton R, Carnero A, Gabri M, Cinat G, Koliren L, et al. Active specific immunotherapy of melanoma with a GM3 ganglioside-based vaccine: a report on safety and immunogenicity. J Immunother. 2004;27:442-51 pubmed
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Nissinen R, Leirisalo Repo M, Peltomaa R, Palosuo T, Vaarala O. Cytokine and chemokine receptor profile of peripheral blood mononuclear cells during treatment with infliximab in patients with active rheumatoid arthritis. Ann Rheum Dis. 2004;63:681-7 pubmed
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Kleen T, Asaad R, Landry S, Boehm B, Tary Lehmann M. Tc1 effector diversity shows dissociated expression of granzyme B and interferon-gamma in HIV infection. AIDS. 2004;18:383-92 pubmed
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Schotte H, Schluter B, Willeke P, Mickholz E, Schorat M, Domschke W, et al. Long-term treatment with etanercept significantly reduces the number of proinflammatory cytokine-secreting peripheral blood mononuclear cells in patients with rheumatoid arthritis. Rheumatology (Oxford). 2004;43:960-4 pubmed
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Ott P, Berner B, Herzog B, Guerkov R, Yonkers N, Durinovic Bello I, et al. CD28 costimulation enhances the sensitivity of the ELISPOT assay for detection of antigen-specific memory effector CD4 and CD8 cell populations in human diseases. J Immunol Methods. 2004;285:223-35 pubmed
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Rasmussen A, Zocca M, Bonefeld C, von Essen M, Lauritsen J, Tomra S, et al. Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen. Scand J Immunol. 2004;59:220-7 pubmed
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Maitra B, Szekely E, Gjini K, Laughlin M, Dennis J, Haynesworth S, et al. Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation. Bone Marrow Transplant. 2004;33:597-604 pubmed
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Manfras B, Reuter S, Wendland T, Boehm B, Kern P. Impeded Th1 CD4 memory T cell generation in chronic-persisting liver infection with Echinococcus multilocularis. Int Immunol. 2004;16:43-50 pubmed
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Tambur A. Monitoring indirect presentation of alloantigens by utilizing the autologous processing machinery of dendritic cells in-vitro. J Immunol Methods. 2003;283:215-23 pubmed
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Guerkov R, Targoni O, Kreher C, Boehm B, Herrera M, Tary Lehmann M, et al. Detection of low-frequency antigen-specific IL-10-producing CD4(+) T cells via ELISPOT in PBMC: cognate vs. nonspecific production of the cytokine. J Immunol Methods. 2003;279:111-21 pubmed
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Kreher C, Dittrich M, Guerkov R, Boehm B, Tary Lehmann M. CD4+ and CD8+ cells in cryopreserved human PBMC maintain full functionality in cytokine ELISPOT assays. J Immunol Methods. 2003;278:79-93 pubmed
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Mannering S, Purcell A, Honeyman M, McCluskey J, Harrison L. Human T-cells recognise N-terminally Fmoc-modified peptide. Vaccine. 2003;21:3638-46 pubmed
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Tsunoda M, Litonjua A, Kuniak M, Weiss S, Satoh T, Guevarra L, et al. Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women. Int Arch Allergy Immunol. 2003;130:158-64 pubmed
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Moore M, Kurago Z, Fullenkamp C, Lutz C. Squamous cell carcinoma cells differentially stimulate NK cell effector functions: the role of IL-18. Cancer Immunol Immunother. 2003;52:107-15 pubmed
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Salerno Goncalves R, Wyant T, Pasetti M, Fernandez Vina M, Tacket C, Levine M, et al. Concomitant induction of CD4+ and CD8+ T cell responses in volunteers immunized with Salmonella enterica serovar typhi strain CVD 908-htrA. J Immunol. 2003;170:2734-41 pubmed
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Xainli J, Baisor M, Kastens W, Bockarie M, Adams J, King C. Age-dependent cellular immune responses to Plasmodium vivax Duffy binding protein in humans. J Immunol. 2002;169:3200-7 pubmed
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Salerno Goncalves R, Pasetti M, Sztein M. Characterization of CD8(+) effector T cell responses in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine. J Immunol. 2002;169:2196-203 pubmed
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Libraty D, Endy T, Houng H, Green S, Kalayanarooj S, Suntayakorn S, et al. Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections. J Infect Dis. 2002;185:1213-21 pubmed
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Wurtzen P, Claesson M. A HLA-A2 restricted human CTL line recognizes a novel tumor cell expressed p53 epitope. Int J Cancer. 2002;99:568-72 pubmed
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Shi Y, Lutz C. Interferon--gamma control of EBV-transformed B cells: a role for CD8+ T cells that poorly kill EBV-infected cells. Viral Immunol. 2002;15:213-25 pubmed
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Hancock G, Scheuer C, Sierzega R, Pryharski K, McBride J, Watelet L, et al. Adaptive immune responses of patients with asthma to the attachment (G) glycoprotein of respiratory synctial virus. J Infect Dis. 2001;184:1589-93 pubmed
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Hioe C, Tuen M, Chien P, Jones G, Ratto Kim S, Norris P, et al. Inhibition of human immunodeficiency virus type 1 gp120 presentation to CD4 T cells by antibodies specific for the CD4 binding domain of gp120. J Virol. 2001;75:10950-7 pubmed
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King C, Malhotra I, Mungai P, Wamachi A, Kioko J, Muchiri E, et al. Schistosoma haematobium-induced urinary tract morbidity correlates with increased tumor necrosis factor-alpha and diminished interleukin-10 production. J Infect Dis. 2001;184:1176-82 pubmed
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Hesse M, Karulin A, Boehm B, Lehmann P, Tary Lehmann M. A T cell clone's avidity is a function of its activation state. J Immunol. 2001;167:1353-61 pubmed
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Valdez H, Anthony D, Farukhi F, Patki A, Salkowitz J, Heeger P, et al. Immune responses to hepatitis C and non-hepatitis C antigens in hepatitis C virus infected and HIV-1 coinfected patients. AIDS. 2000;14:2239-46 pubmed
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Gasche C, Bakos S, Dejaco C, Tillinger W, Zakeri S, Reinisch W. IL-10 secretion and sensitivity in normal human intestine and inflammatory bowel disease. J Clin Immunol. 2000;20:362-70 pubmed
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Wierda W, Cantwell M, Woods S, Rassenti L, Prussak C, Kipps T. CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia. Blood. 2000;96:2917-24 pubmed
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Hartig C, Haller G, Sachs D, Kuhlenschmidt S, Heeger P. Naturally developing memory T cell xenoreactivity to swine antigens in human peripheral blood lymphocytes. J Immunol. 2000;164:2790-6 pubmed
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Heeger P, Greenspan N, Kuhlenschmidt S, Dejelo C, Hricik D, Schulak J, et al. Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J Immunol. 1999;163:2267-75 pubmed
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Malhotra I, Mungai P, Wamachi A, Kioko J, Ouma J, Kazura J, et al. Helminth- and Bacillus Calmette-Guérin-induced immunity in children sensitized in utero to filariasis and schistosomiasis. J Immunol. 1999;162:6843-8 pubmed
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Steenbakkers P, Boots A, Rijnders A. T-cell anergy induced by clonotype-specific antibodies: modulation of an autoreactive human T-cell clone in vitro. Immunology. 1999;96:586-94 pubmed
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Stenger S, Niazi K, Modlin R. Down-regulation of CD1 on antigen-presenting cells by infection with Mycobacterium tuberculosis. J Immunol. 1998;161:3582-8 pubmed
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Medhat A, Shehata M, Bucci K, Mohamed S, Dief A, Badary S, et al. Increased interleukin-4 and interleukin-5 production in response to Schistosoma haematobium adult worm antigens correlates with lack of reinfection after treatment. J Infect Dis. 1998;178:512-9 pubmed
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Secrist H, Levy S, DeKruyff R, Umetsu D. Ligation of TAPA-1 (CD81) or major histocompatibility complex class II in co-cultures of human B and T lymphocytes enhances interleukin-4 synthesis by antigen-specific CD4+ T cells. Eur J Immunol. 1996;26:1435-42 pubmed
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Kubin M, Kamoun M, Trinchieri G. Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells. J Exp Med. 1994;180:211-22 pubmed
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Nakai I, Oka T, Field J, Najarian J, Sutherland D, Brayman K. Neonatal tolerance induction in diabetes-prone BB rats as a model for donor-specific pancreas transplantation during adulthood. Transplant Proc. 1992;24:2902 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IFN丙单克隆抗体(B133.5)
目录# :
M701
规格 :
500微克
定价 :
美国428
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 1:100, Western Blot: 2 µg/mL
物种 :
人类
克隆 :
B133.5
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines. Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. IFN gamma gene mutations are associated with aplastic anemia.
免疫原 :
重组人类IFN丙
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:100, Western Blot: 2 µg/mL
别名 :
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g
更多信息或购买 :
公司信息
赛默飞世尔