产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
脂联素单克隆抗体(19F1)
目录 :
MA1-054
规格 :
100微克
价格 :
美国441.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
19F1
反应物种 :
人类, 小鼠, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; domestic rabbit; 图 3
Cawthorn W, Scheller E, Parlee S, Pham H, Learman B, Redshaw C, et al. Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia. Endocrinology. 2016;157:508-21 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Davis G, Stephens J, Nelson A. Effect of 12 Weeks of Periodized Resistance Training Upon Total Plasma Adiponectin Concentration in Healthy Young Men. J Strength Cond Res. 2015;29:3097-104 pubmed 出版商
  • 免疫印迹; 小鼠
Fuller S, Richard A, Ribnicky D, Beyl R, Mynatt R, Stephens J. St. John's Wort Has Metabolically Favorable Effects on Adipocytes In Vivo. Evid Based Complement Alternat Med. 2014;2014:862575 pubmed 出版商
  • 免疫印迹; 人类
Richard A, Amini Vaughan Z, Ribnicky D, Stephens J. Naringenin inhibits adipogenesis and reduces insulin sensitivity and adiponectin expression in adipocytes. Evid Based Complement Alternat Med. 2013;2013:549750 pubmed 出版商
  • 免疫印迹; 小鼠
Du B, Cawthorn W, Su A, Doucette C, Yao Y, Hemati N, et al. The transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor-? (TGF?) signaling. J Biol Chem. 2013;288:3036-47 pubmed 出版商
  • 免疫印迹; 人类; 0.2 ng/ml
Vidal C, Gunaratnam K, Tong J, Duque G. Biochemical changes induced by strontium ranelate in differentiating adipocytes. Biochimie. 2013;95:793-8 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Seese R, Babayan A, Katz A, Cox C, Lauterborn J, Lynch G, et al. LTP induction translocates cortactin at distant synapses in wild-type but not Fmr1 knock-out mice. J Neurosci. 2012;32:7403-13 pubmed 出版商
  • 免疫印迹; 小鼠
Park Y, Lee Y, Kim S, Lee E, Kim K, Williams D, et al. Snail, a transcriptional regulator, represses adiponectin expression by directly binding to an E-box motif in the promoter. Metabolism. 2012;61:1622-32 pubmed 出版商
  • 免疫印迹; 人类
Boccara F, Auclair M, Cohen A, Lefèvre C, Prot M, Bastard J, et al. HIV protease inhibitors activate the adipocyte renin angiotensin system. Antivir Ther. 2010;15:363-75 pubmed 出版商
  • 免疫印迹; 小鼠
Vernochet C, Davis K, Scherer P, Farmer S. Mechanisms regulating repression of haptoglobin production by peroxisome proliferator-activated receptor-gamma ligands in adipocytes. Endocrinology. 2010;151:586-94 pubmed 出版商
Wang T, Hill R, Dzieciatkowska M, Zhu L, Infante A, Hu G, et al. Site-Dependent Lineage Preference of Adipose Stem Cells. Front Cell Dev Biol. 2020;8:237 pubmed 出版商
Jorgensen A, Varkey M, Gorkun A, Clouse C, Xu L, Chou Z, et al. Bioprinted Skin Recapitulates Normal Collagen Remodeling in Full-Thickness Wounds. Tissue Eng Part A. 2020;26:512-526 pubmed 出版商
El Ouarrat D, Isaac R, Lee Y, Oh D, Wollam J, Lackey D, et al. TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance. Cell Metab. 2020;31:162-173.e5 pubmed 出版商
Seo J, Riopel M, Cabrales P, Huh J, Bandyopadhyay G, Andreyev A, et al. Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity. Nat Metab. 2019;1:86-97 pubmed 出版商
Rotter D, Peiris H, Grinsfelder D, Martin A, Burchfield J, Parra V, et al. Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis. EMBO Rep. 2018;19: pubmed 出版商
Chan C, Gulati G, Sinha R, Tompkins J, Lopez M, Carter A, et al. Identification of the Human Skeletal Stem Cell. Cell. 2018;175:43-56.e21 pubmed 出版商
Gulati G, Bennett M, Abulaban K, Song H, Zhang X, Ma Q, et al. Prospective validation of a novel renal activity index of lupus nephritis. Lupus. 2017;26:927-936 pubmed 出版商
Cawthorn W, Scheller E, Learman B, Parlee S, Simon B, Mori H, et al. Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction. Cell Metab. 2014;20:368-375 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA1-054 图像 1
Immunohistochemistry was performed on biopsies of deparaffinized Human skin tissue. To expose target proteins, heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1:20 with a mouse monoclonal antibody recognizing Adiponectin (MA1-054) or without primary antibody (negative control) overnight at 4°C in a humidified chamber. Tissues were washed extensively with PBST and endogenous peroxidase activity was quenched with a peroxidase suppressor. Detection was performed using a biotin-conjugated secondary antibody and SA-HRP, followed by colorimetric detection using DAB. Tissues were counterstained with hematoxylin and prepped for mounting.
图像 2 :
赛默飞世尔 MA1-054 图像 2
产品信息
产品类型 :
抗体
产品名称 :
脂联素单克隆抗体(19F1)
目录# :
MA1-054
规格 :
100微克
价格 :
美国441.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 兔
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 2 µg/mL
物种 :
人类, 小鼠, 兔
克隆 :
19F1
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling.
免疫原 :
全长, 重组, 人类脂联素
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 2 µg/mL
别名 :
30 kDa adipocyte complement-related protein; 30kDa; Acdc; Acrp30; Ad; adipo; adipocyte complement related protein; adipocyte complement related protein of 30 kDa; adipocyte complement-related 30 kDa protein; adipocyte complement-related protein of 30 kDa; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; adiponectin; adiponectin, C1Q and collagen domain containing; Adipoq; Adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPIOQ; ADPN; Apm1; APM-1; APN; GBP28; Gelatin-binding protein; gelatin-binding protein 28
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国