产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
粘蛋白1单克隆抗体(GP1.4)
目录 :
MA1-06503
规格 :
100微克
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
GP1.4
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1f
Kato K, Uchino R, Lillehoj E, Knox K, Lin Y, Kim K. Membrane-Tethered MUC1 Mucin Counter-Regulates the Phagocytic Activity of Macrophages. Am J Respir Cell Mol Biol. 2016;54:515-23 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 5
  • 流式细胞仪; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Li Q, Liu G, Yuan H, Wang J, Guo Y, Chen T, et al. Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21(WAF1) pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells. Oncotarget. 2015;6:4253-65 pubmed
  • 免疫组化; 人类; 1:400
BaÅŸak K, KiroÄŸlu K. Multiple oncocytic cystadenoma with intraluminal crystalloids in parotid gland: case report. Medicine (Baltimore). 2014;93:e246 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Abdelzaher E, Abdallah D. Expression of mesothelioma-related markers in meningiomas: an immunohistochemical study. Biomed Res Int. 2014;2014:968794 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠; 1:2000
Wang F, Li Q, Ni W, Fang F, Sun X, Xie F, et al. Expression of human full-length MUC1 inhibits the proliferation and migration of a B16 mouse melanoma cell line. Oncol Rep. 2013;30:260-8 pubmed 出版商
  • 免疫组化; 人类; 1:500
Lau P, Yau D, Lau W, Mak L, Chan J. Multinodular reticular schwannoma in the head and neck region: a potential diagnostic pitfall. Int J Surg Pathol. 2013;21:54-8 pubmed 出版商
  • 免疫细胞化学; 人类
Hisatsune A, Nakayama H, Kawasaki M, Horie I, Miyata T, Isohama Y, et al. Anti-MUC1 antibody inhibits EGF receptor signaling in cancer cells. Biochem Biophys Res Commun. 2011;405:377-81 pubmed 出版商
  • 免疫组化; 人类
Metallo C, Azarin S, Moses L, Ji L, de Pablo J, Palecek S. Human embryonic stem cell-derived keratinocytes exhibit an epidermal transcription program and undergo epithelial morphogenesis in engineered tissue constructs. Tissue Eng Part A. 2010;16:213-23 pubmed 出版商
  • 免疫组化; 人类; 1:100
Kelten C, Kabukcu S, Sen N, Teke Z, Yaren A, Erdem E, et al. Secondary involvement of the breast in T-cell non-Hodgkin lymphoma, an unusual example mimicking inflammatory breast carcinoma. Arch Gynecol Obstet. 2009;280:149-52 pubmed 出版商
  • 免疫组化; 人类
Vardar E, Gunlusoy B, Arslan M, Kececi S. Myointimoma of the glans penis. Pathol Int. 2007;57:158-61 pubmed
  • 免疫组化; 人类; 1:1000
Yilmazbayhan D, Ates L, Dilege S, Gulluoglu M, Tanju S, Kalayci G. Pulmonary large cell carcinoma with rhabdoid phenotype. Ann Diagn Pathol. 2005;9:223-6 pubmed
Stanley C, Phillips T. Selective secretion and replenishment of discrete mucin glycoforms from intestinal goblet cells. Am J Physiol. 1999;277:G191-200 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
粘蛋白1单克隆抗体(GP1.4)
目录# :
MA1-06503
规格 :
100微克
价格 :
美国425.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 1:25-1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:25-1:200, Immunohistochemistry (Paraffin): 1:25-1:200, Western Blot: 1:100-1:1,000
物种 :
人类
克隆 :
GP1.4
抗体亚型 :
IgG1
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
MUC1 (Mucin 1, Episialin, MAM-6, CA 15-3, PEM and EMA) is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. MUC1 is a transmembrane glycoprotein with a large mucin-like extracellular domain that matures through several intermediate forms generated by proteolysis, and sequential addition and processing of numerous O-linked glycans that are heavily sialylated. MUC1 is highly polymorphic and each allele encodes a product that contains a different number of repeats (between 30 and 90) leading to large differences in molecular weight of the protein. MUC1 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells, and is expressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. Overexpression, aberrant intracellular localization, and changes in glycosylation of the MUC1 protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of the MUC1 gene have been reported, but the full-length nature of only some has been determined. Transgenic MUC-1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands.
免疫原 :
Human milk fat globule.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:25-1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:25-1:200, Immunohistochemistry (Paraffin): 1:25-1:200, Western Blot: 1:100-1:1,000
别名 :
ADMCKD; ADMCKD1; Breast carcinoma-associated antigen DF3; CA 15-3; Cancer antigen 15-3; carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; J19; KL-6; Krebs von den Lungen-6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease, autosomal dominant; Muc1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin1; mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen; Tumor-associated mucin
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国