产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD19单克隆抗体(4G7)
目录 :
MA1-10126
规格 :
100微克
价格 :
美国235.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4G7
反应物种 :
人类
应用 :
免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 4
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Sathler Avelar R, Vitelli Avelar D, Massara R, de Lana M, Pinto Dias J, Teixeira Carvalho A, et al. Etiological treatment during early chronic indeterminate Chagas disease incites an activated status on innate and adaptive immunity associated with a type 1-modulated cytokine pattern. Microbes Infect. 2008;10:103-13 pubmed 出版商
|
| Martins M, Silva M, Marciano A, Peruhype Magalhães V, Eloi Santos S, Ribeiro J, et al. Activation/modulation of adaptive immunity emerges simultaneously after 17DD yellow fever first-time vaccination: is this the key to prevent severe adverse reactions following immunization?. Clin Exp Immunol. 2007;148:90-100 pubmed
|
| Muench M, Roncarolo M, Menon S, Xu Y, Kastelein R, Zurawski S, et al. FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver. Blood. 1995;85:963-72 pubmed
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Dieu Nosjean M, Massacrier C, Homey B, Vanbervliet B, Pin J, Vicari A, et al. Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. J Exp Med. 2000;192:705-18 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD19单克隆抗体(4G7)
目录# :
MA1-10126
规格 :
100微克
价格 :
美国235.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 1 µg/mL, Immunocytochemistry: Assay-dependent
物种 :
人类
克隆 :
4G7
抗体亚型 :
IgG1, kappa
储存 :
4° C, 不冻结
描述 :
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
免疫原 :
人类CCL(慢性淋巴细胞白血病)细胞
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/mL, Immunocytochemistry: Assay-dependent
别名 :
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
更多信息或购买 :
公司信息
赛默飞世尔