产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
EpCAM单克隆抗体(VU-1D9)
目录 :
MA1-10195
规格 :
100微克
价格 :
美国275.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
VU-1D9
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:50; 图 2c,3
Grzelak C, Sigglekow N, Tirnitz Parker J, Hamson E, Warren A, Maneck B, et al. Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease. PLoS ONE. 2017;12:e0171480 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Kershaw S, Cummings J, Morris K, Tugwood J, Dive C. Optimisation of immunofluorescence methods to determine MCT1 and MCT4 expression in circulating tumour cells. BMC Cancer. 2015;15:387 pubmed 出版商
  • 免疫细胞化学; 人类; 0.75 ug/ml
Shah P, Herrera Loeza S, Sims C, Yeh J, Allbritton N. Small sample sorting of primary adherent cells by automated micropallet imaging and release. Cytometry A. 2014;85:642-9 pubmed 出版商
  • 免疫细胞化学; 人类
Becker T, Caixeiro N, Lim S, Tognela A, Kienzle N, Scott K, et al. New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use. Int J Cancer. 2014;134:2523-33 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Nasarre P, Gemmill R, Potiron V, Roche J, Lu X, Baron A, et al. Neuropilin-2 Is upregulated in lung cancer cells during TGF-?1-induced epithelial-mesenchymal transition. Cancer Res. 2013;73:7111-21 pubmed 出版商
  • 流式细胞仪; 人类
Mosoyan G, Nagi C, Marukian S, Teixeira A, Simonian A, Resnick Silverman L, et al. Multiple breast cancer cell-lines derived from a single tumor differ in their molecular characteristics and tumorigenic potential. PLoS ONE. 2013;8:e55145 pubmed 出版商
  • 免疫组化; 人类; 1:200
Bauerschlag D, Bräutigam K, Moll R, Sehouli J, Mustea A, Salehin D, et al. Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary. J Cancer Res Clin Oncol. 2013;139:347-55 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
  • 免疫细胞化学; 人类; 1:100
Khoja L, Backen A, Sloane R, Menasce L, Ryder D, Krebs M, et al. A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker. Br J Cancer. 2012;106:508-16 pubmed 出版商
  • 免疫印迹; 人类
Horio M, Sato M, Takeyama Y, Elshazley M, Yamashita R, Hase T, et al. Transient but not stable ZEB1 knockdown dramatically inhibits growth of malignant pleural mesothelioma cells. Ann Surg Oncol. 2012;19 Suppl 3:S634-45 pubmed 出版商
  • 免疫组化; 人类
Ligtenberg M, Kuiper R, Chan T, Goossens M, Hebeda K, Voorendt M, et al. Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1. Nat Genet. 2009;41:112-7 pubmed 出版商
  • 免疫组化; 人类; 1:200
Meinhold Heerlein I, Bauerschlag D, Hilpert F, Dimitrov P, Sapinoso L, Orlowska Volk M, et al. Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential. Oncogene. 2005;24:1053-65 pubmed
Sowamber R, Chehade R, Bitar M, Dodds L, Milea A, Slomovitz B, et al. CCAAT/enhancer binding protein delta (C/EBPδ) demonstrates a dichotomous role in tumour initiation and promotion of epithelial carcinoma. EBioMedicine. 2019;: pubmed 出版商
Nicolazzo C, Colangelo L, Corsi A, Carpino G, Gradilone A, Sonato C, et al. Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma. Anal Cell Pathol (Amst). 2018;2018:9718585 pubmed 出版商
Sansone P, Berishaj M, Rajasekhar V, Ceccarelli C, Chang Q, Strillacci A, et al. Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles. Cancer Res. 2017;77:1927-1941 pubmed 出版商
Quintanilla R, Asprer J, Sylakowski K, Lakshmipathy U. Kinetic Measurement and Real Time Visualization of Somatic Reprogramming. J Vis Exp. 2016;: pubmed 出版商
Schaner M, Ross D, Ciaravino G, Sorlie T, Troyanskaya O, Diehn M, et al. Gene expression patterns in ovarian carcinomas. Mol Biol Cell. 2003;14:4376-86 pubmed
产品信息
产品类型 :
抗体
产品名称 :
EpCAM单克隆抗体(VU-1D9)
目录# :
MA1-10195
规格 :
100微克
价格 :
美国275.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 1-3 µg/mL, Immunocytochemistry: 4 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 5-10 µg/mL, Immunoprecipitation: 1-2 µg/mL, Western Blot: 1-4 µg/mL
物种 :
人类
克隆 :
VU-1D9
抗体亚型 :
IgG1
储存 :
4° C, 不冻结
描述 :
Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in the epithelium with a molecular weight of approximately 40 kDa, which functions as an epithelial cell adhesion molecule. Ep-CAM functions as a homotypic calcium-independent cell adhesion molecule, and has a direct impact on cell cycle, proliferation and metabolism of epithelial cells and fibroblasts due to its ability to rapidly induce the proto-oncogene c-myc and the cell cycle regulating genes cyclin A and E. Ep-CAM mediates Ca2+-independent homotypic interactions. Formation of Ep-CAM-mediated adhesions have a negative regulatory effect on adhesions mediated by classic cadherins, which may have strong effects on the differentiation and growth of epithelial cells. Ep-CAM overexpression was suggested to be associated with enhanced epithelial proliferation. Ep-CAM is highly expressed in human carcinomas, and is a marker for tumors of epithelial lineage. Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and many carcinoma types. Also, Ep-CAM reportedly distinguishes adenocarcinomas from pleural mesotheliomas.
免疫原 :
Small cell lung carcinoma cell line H69.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1-3 µg/mL, Immunocytochemistry: 4 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 5-10 µg/mL, Immunoprecipitation: 1-2 µg/mL, Western Blot: 1-4 µg/mL
别名 :
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国