产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD86单克隆抗体(BU63)
目录 :
MA1-10293
规格 :
100微克
价格 :
美国228.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
BU63
反应物种 :
baboons, 人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 34
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 3d
Mytych J, Romerowicz Misielak M, Koziorowski M. Long-term culture with lipopolysaccharide induces dose-dependent cytostatic and cytotoxic effects in THP-1 monocytes. Toxicol In Vitro. 2017;42:1-9 pubmed 出版商
  • 流式细胞仪; 人类; 图 8
Babu R, Brown A. A consensus surface activation marker signature is partially dependent on human immunodeficiency virus type 1 Nef expression within productively infected macrophages. Retrovirology. 2013;10:155 pubmed 出版商
  • 流式细胞仪; 人类
St Gelais C, Coleman C, Wang J, Wu L. HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation. PLoS ONE. 2012;7:e34521 pubmed 出版商
  • 流式细胞仪; 人类; 表 3
Garbe K, Bratke K, Wagner S, Virchow J, Lommatzsch M. Plasmacytoid dendritic cells and their Toll-like receptor 9 expression selectively decrease with age. Hum Immunol. 2012;73:493-7 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Kim J, Kim Y, Jeoung D, Choe J. Human follicular dendritic cells promote the APC capability of B cells by enhancing CD86 expression levels. Cell Immunol. 2012;273:109-14 pubmed 出版商
  • 流式细胞仪; 人类; 表 1
Jones H, Klein N, Dixon G. Human dendritic cell culture and bacterial infection. Methods Mol Biol. 2012;799:217-35 pubmed 出版商
  • 流式细胞仪; 人类
Coleman C, Spearman P, Wu L. Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef. Retrovirology. 2011;8:26 pubmed 出版商
  • 流式细胞仪; 人类; 图 5
Schrauf C, Kirchberger S, Majdic O, Seyerl M, Zlabinger G, Stuhlmeier K, et al. The ssRNA genome of human rhinovirus induces a type I IFN response but fails to induce maturation in human monocyte-derived dendritic cells. J Immunol. 2009;183:4440-8 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Kuhne M, Erben U, Schulze Tanzil G, Köhler D, Wu P, Richter F, et al. HLA-B27-restricted antigen presentation by human chondrocytes to CD8+ T cells: potential contribution to local immunopathologic processes in ankylosing spondylitis. Arthritis Rheum. 2009;60:1635-46 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Stephens T, Nikoopour E, Rider B, Leon Ponte M, Chau T, Mikolajczak S, et al. Dendritic cell differentiation induced by a self-peptide derived from apolipoprotein E. J Immunol. 2008;181:6859-71 pubmed
  • 流式细胞仪; 人类; 图 3
Jacobi A, Reiter K, Mackay M, Aranow C, Hiepe F, Radbruch A, et al. Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95. Arthritis Rheum. 2008;58:1762-73 pubmed 出版商
  • 流式细胞仪; 人类; 表 1
Kolar G, Mehta D, Pelayo R, Capra J. A novel human B cell subpopulation representing the initial germinal center population to express AID. Blood. 2007;109:2545-52 pubmed
  • 流式细胞仪; 人类; 表 2
  • 免疫细胞化学; 人类; 图 2h
Sandilands G, McCrae J, Hill K, Perry M, Baxter D. Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils. Immunology. 2006;119:562-71 pubmed
  • 流式细胞仪; 人类
Summers K, Marleau A, Mahon J, McManus R, Hramiak I, Singh B. Reduced IFN-alpha secretion by blood dendritic cells in human diabetes. Clin Immunol. 2006;121:81-9 pubmed
  • 流式细胞仪; 人类; 图 1
Reis E, Barbuto J, Isaac L. Human monocyte-derived dendritic cells are a source of several complement proteins. Inflamm Res. 2006;55:179-84 pubmed
  • 流式细胞仪; 人类
Lopez Santalla M, Valeri A, Perez Blas M, Aguilera Montilla N, Gutierrez A, Lasa I, et al. Expression of CD45 and proliferative response to CD3 as suitable classification markers of patients with gastric adenocarcinoma. Cancer Immunol Immunother. 2006;55:744-8 pubmed
  • 流式细胞仪; 人类; 图 4
Kirchberger S, Majdic O, Steinberger P, Bluml S, Pfistershammer K, Zlabinger G, et al. Human rhinoviruses inhibit the accessory function of dendritic cells by inducing sialoadhesin and B7-H1 expression. J Immunol. 2005;175:1145-52 pubmed
  • 流式细胞仪; 人类; 图 1
Bluml S, Kirchberger S, Bochkov V, Kronke G, Stuhlmeier K, Majdic O, et al. Oxidized phospholipids negatively regulate dendritic cell maturation induced by TLRs and CD40. J Immunol. 2005;175:501-8 pubmed
  • 流式细胞仪; 人类; 3.3 ug/ml
McIlroy D, Tanguy Royer S, Le Meur N, Guisle I, Royer P, Léger J, et al. Profiling dendritic cell maturation with dedicated microarrays. J Leukoc Biol. 2005;78:794-803 pubmed
  • 流式细胞仪; 人类
Game D, Rogers N, Lechler R. Acquisition of HLA-DR and costimulatory molecules by T cells from allogeneic antigen presenting cells. Am J Transplant. 2005;5:1614-25 pubmed
  • 流式细胞仪; 人类; 表 1
Lozza L, Lilleri D, Percivalle E, Fornara C, Comolli G, Revello M, et al. Simultaneous quantification of human cytomegalovirus (HCMV)-specific CD4+ and CD8+ T cells by a novel method using monocyte-derived HCMV-infected immature dendritic cells. Eur J Immunol. 2005;35:1795-804 pubmed
  • 流式细胞仪; 人类
Aguilera Montilla N, Perez Blas M, Valeri A, Lopez Santalla M, Rodríguez Juan C, Mencia A, et al. Higher proliferative capacity of T lymphocytes from patients with Crohn disease than from ulcerative colitis is disclosed by use of Herpesvirus saimiri-transformed T-cell lines. Scand J Gastroenterol. 2004;39:1236-42 pubmed
  • 流式细胞仪; 人类; 图 1
Kudela P, Paukner S, Mayr U, Cholujova D, Schwarczova Z, Sedlak J, et al. Bacterial ghosts as novel efficient targeting vehicles for DNA delivery to the human monocyte-derived dendritic cells. J Immunother. 2005;28:136-43 pubmed
  • 流式细胞仪; 人类; 图 6
Sandilands G, Ahmed Z, Perry N, Davison M, Lupton A, Young B. Cross-linking of neutrophil CD11b results in rapid cell surface expression of molecules required for antigen presentation and T-cell activation. Immunology. 2005;114:354-68 pubmed
  • 流式细胞仪; 人类; 图 4
Pfistershammer K, Majdic O, Stockl J, Zlabinger G, Kirchberger S, Steinberger P, et al. CD63 as an activation-linked T cell costimulatory element. J Immunol. 2004;173:6000-8 pubmed
  • 流式细胞仪; 人类
Zingoni A, Sornasse T, Cocks B, Tanaka Y, Santoni A, Lanier L. Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions. J Immunol. 2004;173:3716-24 pubmed
  • 流式细胞仪; baboons
Frost P, Hubbard G, Dammann M, Snider C, Moore C, Hodara V, et al. White monkey syndrome in infant baboons (Papio species). J Med Primatol. 2004;33:197-213 pubmed
  • 流式细胞仪; 人类
Valeri A, Perez Blas M, Gutierrez A, Lopez Santalla M, Aguilera N, Rodríguez Juan C, et al. Intrinsic defects explain altered proliferative responses of T lymphocytes and HVS-derived T-cell lines in gastric adenocarcinoma. Cancer Immunol Immunother. 2003;52:708-14 pubmed
  • 酶联免疫吸附测定; 人类; 图 6
Selenko Gebauer N, Majdic O, Szekeres A, Höfler G, Guthann E, Korthauer U, et al. B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy. J Immunol. 2003;170:3637-44 pubmed
  • 流式细胞仪; 人类
McDowell M, Marovich M, Lira R, Braun M, Sacks D. Leishmania priming of human dendritic cells for CD40 ligand-induced interleukin-12p70 secretion is strain and species dependent. Infect Immun. 2002;70:3994-4001 pubmed
  • 流式细胞仪; 人类; 图 3
Berg L, James M, Alvarez Iglesias M, Glennie S, Lechler R, Marelli Berg F. Functional consequences of noncognate interactions between CD4+ memory T lymphocytes and the endothelium. J Immunol. 2002;168:3227-34 pubmed
  • 流式细胞仪; 人类
Steinberger P, Szekeres A, Wille S, Stockl J, Selenko N, Prager E, et al. Identification of human CD93 as the phagocytic C1q receptor (C1qRp) by expression cloning. J Leukoc Biol. 2002;71:133-40 pubmed
Hou T, Li S, Zhang G, Li Y. High-fluence low-power laser irradiation promotes odontogenesis and inflammation resolution in periodontitis by enhancing stem cell proliferation and differentiation. Int J Mol Med. 2018;42:2107-2119 pubmed 出版商
Morbach H, Wiegering V, Richl P, Schwarz T, Suffa N, Eichhorn E, et al. Activated memory B cells may function as antigen-presenting cells in the joints of children with juvenile idiopathic arthritis. Arthritis Rheum. 2011;63:3458-66 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD86单克隆抗体(BU63)
目录# :
MA1-10293
规格 :
100微克
价格 :
美国228.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µg/ml, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
物种 :
人类
克隆 :
BU63
抗体亚型 :
IgG1
储存 :
4° C, 不冻结
描述 :
CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms of CD86. Additional transcript variants have been described for CD86, but their full-length sequences have not been determined. Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
免疫原 :
B-lymphoblastoid cell line ARH 77
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µg/ml, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
别名 :
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国