HMOX1单克隆抗体(HO-1-1) | 赛默飞世尔 MA1-112 产品信息

产品简要

公司名称 :

赛默飞世尔

其他品牌 :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

产品类型 :

抗体

产品名称 :

HMOX1单克隆抗体(HO-1-1)

MA1-112

规格 :

200微克

价格 :

美国496.00

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

HO-1-1

反应物种 :

人类, 小鼠, 大鼠, 犬, 牛

应用 :

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片

更多信息或购买 :

赛默飞世尔产品网页

文章摘录数: 21

出版应用/物种/样本/稀释	参考文献
免疫细胞化学; 人类; 1:100; 图 s7b 免疫印迹; 人类; 图 3b	Wang G, Zhou H, Strulovici Barel Y, Al Hijji M, Ou X, Salit J, et al. Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium. Autophagy. 2017;13:1205-1220 pubmed 出版商
免疫印迹; 大鼠; 图 4a	Chen Z, Wang Q. Activation of PPAR? by baicalin attenuates pulmonary hypertension in an infant rat model by suppressing HMGB1/RAGE signaling. FEBS Open Bio. 2017;7:477-484 pubmed 出版商
免疫印迹; 小鼠; 1:500; 图 5a	Lee J, Kim H, Han J, Kim Y, Son C. Anti-fatigue effect of Myelophil in a chronic forced exercise mouse model. Eur J Pharmacol. 2015;764:100-8 pubmed 出版商
免疫印迹; 小鼠; 1:500	Hong S, Lee J, Lee J, Lee H, Kim H, Lee S, et al. The traditional drug Gongjin-Dan ameliorates chronic fatigue in a forced-stress mouse exercise model. J Ethnopharmacol. 2015;168:268-78 pubmed 出版商
	Chen H, Nguyen N, Magtoto C, Cobbold S, Bidgood G, Meza Guzman L, et al. Design and characterization of a heterobifunctional degrader of KEAP1. Redox Biol. 2023;59:102552 pubmed 出版商
	Ren R, Fang Y, Sherchan P, Lu Q, Lenahan C, Zhang J, et al. Kynurenine/Aryl Hydrocarbon Receptor Modulates Mitochondria-Mediated Oxidative Stress and Neuronal Apoptosis in Experimental Intracerebral Hemorrhage. Antioxid Redox Signal. 2022;37:1111-1129 pubmed 出版商
	Soliman S, El Labbad E, Abu Qiyas A, Fayed B, Hamoda A, Al Rawi A, et al. Novel Secreted Peptides From Rhizopus arrhizus var. delemar With Immunomodulatory Effects That Enhance Fungal Pathogenesis. Front Microbiol. 2022;13:863133 pubmed 出版商
	Lawrence M, Elhendawi M, Morlock M, Liu W, Liu S, Palakkan A, et al. Human iPSC-derived renal organoids engineered to report oxidative stress can predict drug-induced toxicity. iScience. 2022;25:103884 pubmed 出版商
	Lin Y, Lin C, Ho E, Ke Y, Petridi S, Elliott C, et al. Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson's disease. elife. 2021;10: pubmed 出版商
	Wu Y, Liang S, Zhu H, Zhu Y. Analysis of immune-related key genes in Alzheimer's disease. Bioengineered. 2021;12:9610-9624 pubmed 出版商
	Ebrahimpour A, Wang M, Li L, Jegga A, Bonnen M, Eissa N, et al. Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway. J Inflamm (Lond). 2021;18:17 pubmed 出版商
	Fige É, Szendrei J, Sós L, Kraszewska I, Potor L, Balla J, et al. Heme Oxygenase-1 Contributes to Both the Engulfment and the Anti-Inflammatory Program of Macrophages during Efferocytosis. Cells. 2021;10: pubmed 出版商
	Eassawy M, Salem A, Ismail A. Biochemical study on the protective effect of curcumin on acetaminophen and gamma-irradiation induced hepatic toxicity in rats. Environ Toxicol. 2020;: pubmed 出版商
	Lombard D, Kohler W, Guo A, Gendron C, Han M, Ding W, et al. High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv. 2020;6: pubmed 出版商
	De Nuccio C, Bernardo A, Troiano C, Brignone M, Falchi M, Greco A, et al. NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation. Int J Mol Sci. 2020;21: pubmed 出版商
	Chen W, Hu S, Mao S, Xu Y, Guo H, Li H, et al. Discovery of Mitochondrial Transcription Inhibitors Active in Pancreatic Cancer Cells. ChemMedChem. 2020;15:2029-2039 pubmed 出版商
	Yi W, Lan H, Wen Y, Wang Y, He D, Bai Z, et al. HO-1 overexpression alleviates senescence by inducing autophagy via the mitochondrial route in human nucleus pulposus cells. J Cell Physiol. 2020;: pubmed 出版商
	Wiel C, Le Gal K, Ibrahim M, Jahangir C, Kashif M, Yao H, et al. BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis. Cell. 2019;: pubmed 出版商
	Gill N, Leng Y, Romero R, Xu Y, Panaitescu B, Miller D, et al. The immunophenotype of decidual macrophages in acute atherosis. Am J Reprod Immunol. 2019;81:e13098 pubmed 出版商
	Forootan S, Mutter F, Kipar A, Iwawaki T, Francis B, Goldring C, et al. Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity. Sci Rep. 2017;7:16084 pubmed 出版商
	Nguyen Ho Bouldoires T, ClapÃ©ron A, Mergey M, Wendum D, Desbois Mouthon C, Tahraoui S, et al. Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to hydrogen peroxide-induced oxidative stress in human hepatobiliary cancer cells. Free Radic Biol Med. 2015;89:34-46 pubmed 出版商

图像

图像 1 :

Immunofluorescent analysis of Heme Oxygenase-1 (HO-1, green) in HeLa cells either left untreated (left panel) or treated with 0.5mM copper sulfate (right panel) for 24 hours. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA (Product # 37525) for 15 minutes at room temperature. Cells were probed with an HO-1 monoclonal antibody (Product # MA1-112) at a dilution of 1:100 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488 goat anti-mouse IgG secondary antibody (Product # 35502) at a dilution of 1:400 for 30 minutes at room temperature. F-Actin (red) was stained with DyLight 554 Phalloidin (Product # 21834) and nuclei (blue) were stained with Hoechst 33342 dye (Product # 62249). Images were taken on a Thermo Scientific ArrayScan or ToxInsight Instrument at 20X magnification.

产品信息

产品类型 :

抗体

产品名称 :

HMOX1单克隆抗体(HO-1-1)

目录# :

MA1-112

规格 :

200微克

价格 :

美国496.00

克隆性 :

单克隆

纯度 :

蛋白质G

宿主 :

小鼠

反应物种 :

牛, 狗, 人类, 小鼠, 大鼠

应用 :

Flow Cytometry: 10 µg/mL, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:1,000

物种 :

牛, 狗, 人类, 小鼠, 大鼠

克隆 :

HO-1-1

抗体亚型 :

IgG1, kappa

储存 :

-20° C, 避免反复冷冻/解冻

描述 :

Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.

免疫原 :

Synthetic peptide corresponding to the sequence near the N-terminus (amino acids 1-30) of human Heme Oxygenase 1

格式 :

液体

应用w/稀释 :

Flow Cytometry: 10 µg/mL, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:1,000

别名 :

bK286B10; D8Wsu38e; heat shock protein 32; heat shock protein, 32-kD; heme orygenase 1; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; heme oxygenase 1; heme oxygenase-1; Hemox; hemoxygenase; Heox; HEOXG; Hmox; Hmox1; HMOX1D; HO; Ho1; HO-1; Hsp32; P32 protein

更多信息或购买 :

赛默飞世尔产品网页

公司信息

赛默飞世尔

上海浦东新金桥路27号7号楼

analyze.cn@thermofisher.com

http://www.thermo.com.cn

1084193588

公司总部: 美国