产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD4单克隆抗体(GK1.5)
目录 :
MA1-146毫克
规格 :
1毫克
价格 :
美国1060.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
GK1.5
反应物种 :
小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 90
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:100; 图 1c
Benkhoucha M, Tran N, Breville G, Senoner I, Bradfield P, Papayannopoulou T, et al. CD4+c-Met+Itgα4+ T cell subset promotes murine neuroinflammation. J Neuroinflammation. 2022;19:103 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3, 1a
Keller E, Dvorina N, Jørgensen T. Spontaneous CD4+ T Cell Activation and Differentiation in Lupus-Prone B6.Nba2 Mice Is IFNAR-Independent. Int J Mol Sci. 2022;23: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Hao W, Luo Q, Menger M, Fassbender K, Liu Y. Treatment With CD52 Antibody Protects Neurons in Experimental Autoimmune Encephalomyelitis Mice During the Recovering Phase. Front Immunol. 2021;12:792465 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s8d
Wang Z, He L, Li W, Xu C, Zhang J, Wang D, et al. GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma. J Immunother Cancer. 2021;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Flamini S, Sergeev P, Viana de Barros Z, Mello T, Biagioli M, Paglialunga M, et al. Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment. Cell Death Dis. 2021;12:421 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3b
Datta M, Staszewski O. Hdac1 and Hdac2 are essential for physiological maturation of a Cx3cr1 expressing subset of T-lymphocytes. BMC Res Notes. 2021;14:135 pubmed 出版商
  • 流式细胞仪; 小鼠
Chu A, Kok S, TSUI J, Lin M, Aguirre B, Wadehra M. Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface. J Reprod Immunol. 2021;145:103309 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Khan T, Hartley A, Haskard D, Caga Anan M, Pennell D, Collins P, et al. Oxidised LDL and Anti-Oxidised LDL Antibodies Are Reduced by Lipoprotein Apheresis in a Randomised Controlled Trial on Patients with Refractory Angina and Elevated Lipoprotein(a). Antioxidants (Basel). 2021;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Herring S, Oda J, Wagoner J, Kirchmeier D, O Connor A, Nelson E, et al. Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs. Antimicrob Agents Chemother. 2021;65: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Mazur Bialy A, Pochec E. The Time-Course of Antioxidant Irisin Activity: Role of the Nrf2/HO-1/HMGB1 Axis. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Webb L, Fra Bido S, Innocentin S, Matheson L, Attaf N, Bignon A, et al. Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ. Aging Cell. 2021;20:e13295 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Zhao L, Hu S, Davila M, Yang J, Lin Y, Albanese J, et al. Coordinated co-migration of CCR10+ antibody-producing B cells with helper T cells for colonic homeostatic regulation. Mucosal Immunol. 2021;14:420-430 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4
Neuper T, Neureiter D, Sarajlic M, Strandt H, Bauer R, Schwarz H, et al. IL-31 transgenic mice show reduced allergen-induced lung inflammation. Eur J Immunol. 2021;51:191-196 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Uhl B, Braun C, Dominik J, Luft J, Canis M, Reichel C. A Novel Experimental Approach for In Vivo Analyses of the Salivary Gland Microvasculature. Front Immunol. 2020;11:604470 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Jin C, Du L, Nuerlan A, Wang X, Yang Y, Guo R. High expression of RRM2 as an independent predictive factor of poor prognosis in patients with lung adenocarcinoma. Aging (Albany NY). 2020;13:3518-3535 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4e
Luoni M, Giannelli S, Indrigo M, Niro A, Massimino L, Iannielli A, et al. Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Witalis M, Chang J, Zhong M, Bouklouch Y, Panneton V, Li J, et al. Progression of AITL-like tumors in mice is driven by Tfh signature proteins and T-B cross talk. Blood Adv. 2020;4:868-879 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 3b
Rosenbaum M, Gewies A, Pechloff K, Heuser C, Engleitner T, Gehring T, et al. Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells. Nat Commun. 2019;10:2352 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Lee Y, Ju J, Shon W, Oh S, Min C, Kang M, et al. Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD. Immune Netw. 2018;18:e44 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Gubernatorova E, Gorshkova E, Namakanova O, Zvartsev R, Hidalgo J, Drutskaya M, et al. Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation. Front Immunol. 2018;9:2718 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 2g
He Z, Zhang J, Huang Z, Du Q, Li N, Zhang Q, et al. Sumoylation of RORγt regulates TH17 differentiation and thymocyte development. Nat Commun. 2018;9:4870 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 ev2c
Er J, Koean R, Ding J. Loss of T-bet confers survival advantage to influenza-bacterial superinfection. EMBO J. 2019;38: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4i
Luo H, Winkelmann E, Zhu S, Ru W, Mays E, Silvas J, et al. Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection. J Clin Invest. 2018;128:4980-4991 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Lin Y, Wang L, Lee C, Chen S. Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses. Sci Rep. 2018;8:12184 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Cheng Y, Zhu X, Wang X, Zhuang Q, Huyan X, Sun X, et al. Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation. Front Immunol. 2018;9:1566 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3c
Baens M, Stirparo R, Lampi Y, Verbeke D, Vandepoel R, Cools J, et al. Malt1 self-cleavage is critical for regulatory T cell homeostasis and anti-tumor immunity in mice. Eur J Immunol. 2018;48:1728-1738 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4c
Manresa Arraut A, Johansen F, Brakebusch C, Issazadeh Navikas S, Hasseldam H. RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis. Front Immunol. 2018;9:1235 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:6; 图 s2a
Gu C, Borjabad A, Hadas E, Kelschenbach J, Kim B, Chao W, et al. EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment. PLoS Pathog. 2018;14:e1007061 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine T, et al. Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression. J Clin Invest. 2018;128:2487-2499 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Safya H, Mellouk A, Legrand J, Le Gall S, Benbijja M, Kanellopoulos Langevin C, et al. Variations in Cellular Responses of Mouse T Cells to Adenosine-5'-Triphosphate Stimulation Do Not Depend on P2X7 Receptor Expression Levels but on Their Activation and Differentiation Stage. Front Immunol. 2018;9:360 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
A Verghese D, Demir M, Chun N, Fribourg M, Cravedi P, Llaudó I, et al. T Cell Expression of C5a Receptor 2 Augments Murine Regulatory T Cell (TREG) Generation and TREG-Dependent Cardiac Allograft Survival. J Immunol. 2018;200:2186-2198 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Liang W, Mao S, Sun S, Li M, Li Z, Yu R, et al. Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation. Front Immunol. 2018;9:78 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Leonardi I, Li X, Semon A, Li D, Doron I, Putzel G, et al. CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi. Science. 2018;359:232-236 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2d
Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Chien C, Yu H, Chen S, Chiang B. Characterization of c-Maf+Foxp3- Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells. Sci Rep. 2017;7:46348 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5d
Inoue T, Shinnakasu R, Ise W, Kawai C, Egawa T, Kurosaki T. The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help. J Exp Med. 2017;214:1181-1198 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:800; 图 s1c
Barthels C, Ogrinc A, Steyer V, Meier S, Simon F, Wimmer M, et al. CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis. Nat Commun. 2017;8:14715 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Szabo P, Goswami A, Mazzuca D, Kim K, O Gorman D, Hess D, et al. Rapid and Rigorous IL-17A Production by a Distinct Subpopulation of Effector Memory T Lymphocytes Constitutes a Novel Mechanism of Toxic Shock Syndrome Immunopathology. J Immunol. 2017;198:2805-2818 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1b
Oh J, Oh D, Jung H, Lee H. A mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract. Proc Natl Acad Sci U S A. 2017;114:E1188-E1195 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Ishiguro T, Fukawa T, Akaki K, Nagaoka K, Takeda T, Iwakura Y, et al. Absence of DCIR1 reduces the mortality rate of endotoxemic hepatitis in mice. Eur J Immunol. 2017;47:704-712 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2c
van Nieuwenhuijze A, Dooley J, Humblet Baron S, Sreenivasan J, Koenders M, Schlenner S, et al. Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice. Cell Mol Life Sci. 2017;74:2095-2106 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Cañete A, Carmona R, Ariza L, Sanchez M, Rojas A, Muñoz Chápuli R. A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice. Haematologica. 2017;102:647-655 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Engler J, Kursawe N, Solano M, Patas K, Wehrmann S, Heckmann N, et al. Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy. Proc Natl Acad Sci U S A. 2017;114:E181-E190 pubmed 出版商
  • 流式细胞仪; 小鼠
Marshall N, Vong A, Devarajan P, Brauner M, Kuang Y, Nayar R, et al. NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection. J Immunol. 2017;198:1142-1155 pubmed 出版商
  • 流式细胞仪; 小鼠
Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani R, Jiménez Andrade G, et al. Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction. J Biol Chem. 2017;292:1762-1772 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Lamprianou S, Gysemans C, Bou Saab J, Pontes H, Mathieu C, Meda P. Glibenclamide Prevents Diabetes in NOD Mice. PLoS ONE. 2016;11:e0168839 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3D
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s6
Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 6a
Coleman C, Sisk J, Halasz G, Zhong J, Beck S, Matthews K, et al. CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome. J Virol. 2017;91: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Massaad M, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, et al. Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. J Clin Invest. 2016;126:4219-4236 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Uckelmann H, Blaszkiewicz S, Nicolae C, Haas S, Schnell A, Wurzer S, et al. Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4. J Exp Med. 2016;213:1961-71 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Henry E, Sy C, Inclan Rico J, Espinosa V, Ghanny S, Dwyer D, et al. Carbonic anhydrase enzymes regulate mast cell-mediated inflammation. J Exp Med. 2016;213:1663-73 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Carow B, Gao Y, Coquet J, Reilly M, Rottenberg M. lck-Driven Cre Expression Alters T Cell Development in the Thymus and the Frequencies and Functions of Peripheral T Cell Subsets. J Immunol. 2016;197:2261-8 pubmed 出版商
  • 流式细胞仪; 小鼠
Seehus C, Kaye J. In vitro Differentiation of Murine Innate Lymphoid Cells from Common Lymphoid Progenitor Cells. Bio Protoc. 2016;6: pubmed
  • 流式细胞仪; 小鼠; 图 5d
Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, et al. FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling. Cancer Res. 2016;76:4124-35 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6
  • 流式细胞仪; 小鼠; 图 6
Stachtea X, Tykesson E, van Kuppevelt T, Feinstein R, Malmström A, Reijmers R, et al. Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis. PLoS ONE. 2015;10:e0140279 pubmed 出版商
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Matsuda Y, Wang X, Oishi H, Guan Z, Saito M, Liu M, et al. Spleen Tyrosine Kinase Modulates Fibrous Airway Obliteration and Associated Lymphoid Neogenesis After Transplantation. Am J Transplant. 2016;16:342-52 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2e
Lowe K, Navarro Núñez L, Bénézech C, Nayar S, Kingston B, Nieswandt B, et al. The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state. Eur J Immunol. 2015;45:2484-93 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6b
  • 免疫组化; 小鼠; 图 3a
Lal G, Nakayama Y, Sethi A, Singh A, Burrell B, Kulkarni N, et al. Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance. Transplantation. 2015;99:1817-28 pubmed 出版商
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Jing W, Gershan J, Weber J, Tlomak D, McOlash L, Sabatos Peyton C, et al. Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma. J Immunother Cancer. 2015;3:2 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Bertin S, Lozano Ruiz B, Bachiller V, García Martínez I, Herdman S, Zapater P, et al. Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice. Mucosal Immunol. 2015;8:505-15 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Griffiths K, Stylianou E, Poyntz H, Betts G, Fletcher H, McShane H. Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice. PLoS ONE. 2013;8:e78312 pubmed 出版商
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Barron L, Knoechel B, Lohr J, Abbas A. Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance. J Immunol. 2008;180:2762-6 pubmed
  • 流式细胞仪; 小鼠; 图 1
Lu M, Tayu R, Ikawa T, Masuda K, Matsumoto I, Mugishima H, et al. The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors. J Immunol. 2005;175:5848-56 pubmed
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Xu H, Wipasa J, Yan H, Zeng M, Makobongo M, Finkelman F, et al. The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection. J Exp Med. 2002;195:881-92 pubmed
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Farrar J, Ouyang W, Lohning M, Assenmacher M, Radbruch A, Kanagawa O, et al. An instructive component in T helper cell type 2 (Th2) development mediated by GATA-3. J Exp Med. 2001;193:643-50 pubmed
  • 流式细胞仪; 小鼠; 图 2
Samoilova E, Horton J, Bassiri H, Zhang H, Linsley P, Carding S, et al. B7 blockade prevents activation-induced cell death of thymocytes. Int Immunol. 1997;9:1663-8 pubmed
  • 流式细胞仪; 小鼠; 图 3
Postel Vinay M, de Mello Coelho V, Gagnerault M, Dardenne M. Growth hormone stimulates the proliferation of activated mouse T lymphocytes. Endocrinology. 1997;138:1816-20 pubmed
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Wu L, Scollay R, Egerton M, Pearse M, Spangrude G, Shortman K. CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus. Nature. 1991;349:71-4 pubmed
Elsayed R, Elashiry M, Liu Y, Morandini A, El Awady A, Elashiry M, et al. Microbially-Induced Exosomes from Dendritic Cells Promote Paracrine Immune Senescence: Novel Mechanism of Bone Degenerative Disease in Mice. Aging Dis. 2023;14:136-151 pubmed 出版商
Zhang Z, Zhai C, Yang X, Li H, Wu L, Li L. Knockdown of CD146 promotes endothelial-to-mesenchymal transition via Wnt/β-catenin pathway. PLoS ONE. 2022;17:e0273542 pubmed 出版商
Deng Z, Teng Y, Zhou Q, Ouyang Z, Hu Y, Long H, et al. Shuyu pills inhibit immune escape and enhance chemosensitization in hepatocellular carcinoma. World J Gastrointest Oncol. 2021;13:1725-1740 pubmed 出版商
Zhu Q, Yuan J, He Y, Hu Y. The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer. J Oncol. 2021;2021:5170496 pubmed 出版商
Liu H, Pedros C, Kong K, Canonigo Balancio A, Xue W, Altman A. Leveraging the Treg-intrinsic CTLA4-PKCη signaling pathway for cancer immunotherapy. J Immunother Cancer. 2021;9: pubmed 出版商
Baloche V, Rivière J, Tran T, Gelin A, Bawa O, Signolle N, et al. Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model. Sci Rep. 2021;11:5227 pubmed 出版商
Lu Y, Zhao Q, Liao J, Song E, Xia Q, Pan J, et al. Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell. 2020;180:1081-1097.e24 pubmed 出版商
Harris M, Fufa T, Palmer J, Joshi S, Larson D, Incao A, et al. A direct link between MITF, innate immunity, and hair graying. PLoS Biol. 2018;16:e2003648 pubmed 出版商
Indrova M, Rossowska J, Pajtasz Piasecka E, Mikyšková R, Richter J, Rosina J, et al. The role of immune cell subpopulations in the growth and rejection of TC-1/A9 tumors in novel mouse strains differing in the H2-D haplotype and NKC domain. Oncol Lett. 2018;15:3594-3601 pubmed 出版商
Perry C, Muñoz Rojas A, Meeth K, Kellman L, Amezquita R, Thakral D, et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med. 2018;215:877-893 pubmed 出版商
Ames R, Ting L, Gendlina I, Kim K, Macian F. The Transcription Factor NFAT1 Participates in the Induction of CD4+ T Cell Functional Exhaustion during Plasmodium yoelii Infection. Infect Immun. 2017;85: pubmed 出版商
Xu X, Han L, Zhao G, Xue S, Gao Y, Xiao J, et al. LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis. J Exp Med. 2017;214:209-226 pubmed 出版商
Fröhlich M, Gogishvili T, Langenhorst D, Luhder F, Hunig T. Interrupting CD28 costimulation before antigen rechallenge affects CD8(+) T-cell expansion and effector functions during secondary response in mice. Eur J Immunol. 2016;46:1644-55 pubmed 出版商
Poczobutt J, Nguyen T, Hanson D, Li H, Sippel T, Weiser Evans M, et al. Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment. J Immunol. 2016;196:891-901 pubmed 出版商
Yang W, Vethanayagam R, Dong Y, Cai Q, Hu B. Activation of the antigen presentation function of mononuclear phagocyte populations associated with the basilar membrane of the cochlea after acoustic overstimulation. Neuroscience. 2015;303:1-15 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD4单克隆抗体(GK1.5)
目录# :
MA1-146毫克
规格 :
1毫克
价格 :
美国1060.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 1:50, Immunocytochemistry: 1:20, Western Blot: 1:1,000
物种 :
小鼠
克隆 :
GK1.5
抗体亚型 :
IgG2b, kappa
储存 :
-20°C
描述 :
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
免疫原 :
小鼠CTL克隆V4
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:50, Immunocytochemistry: 1:20, Western Blot: 1:1,000
别名 :
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国