产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PKC甲单克隆抗体(MC5)
目录 :
MA1-157
规格 :
100微克
价格 :
美国471.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MC5
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, 犬, 牛, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 6
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
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产品信息
产品类型 :
抗体
产品名称 :
PKC甲单克隆抗体(MC5)
目录# :
MA1-157
规格 :
100微克
价格 :
美国471.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Bovine, Canine, Human, Mouse, Non-human primate, Rabbit, Rat
应用 :
Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 5 µg, Western Blot: 1:1,000
物种 :
Bovine, Canine, Human, Mouse, Non-human primate, Rabbit, Rat
克隆 :
MC5
抗体亚型 :
IgG2a
储存 :
-20°C
描述 :
The PKC family of serine/threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. Protein kinase C (PKC) can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
免疫原 :
纯化牛大脑蛋白激酶Cα
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 5 µg, Western Blot: 1:1,000
别名 :
AAG6; aging-associated gene 6; AI875142; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; Pkca; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; Prkca; prkcaa; protein kinase C; protein kinase C alpha; protein kinase C alpha type; protein kinase C alpha type; protein kinase C, alpha, a; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045); unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔