产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
c Myc单克隆抗体(9E11)
目录 :
MA1-16637
规格 :
100微升
价格 :
美国450.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
9E11
反应物种 :
人类, 小鼠, 大鼠, 鸡
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 31
参考文献
Song Y, Hou G, Diep J, Ooi Y, Akopyants N, Beverley S, et al. Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation. Nucleic Acids Res. 2021;49:12706-12715 pubmed 出版商
Ghiselli F, Rossi B, Felici M, Parigi M, Tosi G, Fiorentini L, et al. Isolation, culture, and characterization of chicken intestinal epithelial cells. BMC Mol Cell Biol. 2021;22:12 pubmed 出版商
Yao Y, Yu D, Xu L, Gu T, Li Y, Zheng X, et al. Tupaia OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS. J Immunol. 2020;205:3419-3428 pubmed 出版商
Xu L, Yu D, Fan Y, Peng L, Wu Y, Yao Y. Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew. Proc Natl Acad Sci U S A. 2016;113:10950-5 pubmed 出版商
Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed 出版商
Yeheskely Hayon D, Kotler A, Stark M, Hashimshony T, Sagee S, Kassir Y. The roles of the catalytic and noncatalytic activities of Rpd3L and Rpd3S in the regulation of gene transcription in yeast. PLoS ONE. 2013;8:e85088 pubmed 出版商
Du W, Josephrajan A, Adhikary S, Bowles T, Bielinsky A, Eichman B. Mcm10 self-association is mediated by an N-terminal coiled-coil domain. PLoS ONE. 2013;8:e70518 pubmed 出版商
Inoue M, Yasuda K, Uemura H, Yasaka N, Schnaufer A, Yano M, et al. Trypanosoma brucei 14-3-3I and II proteins predominantly form a heterodimer structure that acts as a potent cell cycle regulator in vivo. J Biochem. 2013;153:431-9 pubmed 出版商
Milliman E, Hu Z, Yu M. Genomic insights of protein arginine methyltransferase Hmt1 binding reveals novel regulatory functions. BMC Genomics. 2012;13:728 pubmed 出版商
Cattoretti G. MYC expression and distribution in normal mature lymphoid cells. J Pathol. 2013;229:430-40 pubmed 出版商
Milliman E, Yadav N, Chen Y, Muddukrishna B, Karunanithi S, Yu M. Recruitment of Rpd3 to the telomere depends on the protein arginine methyltransferase Hmt1. PLoS ONE. 2012;7:e44656 pubmed 出版商
Kulemzina I, Schumacher M, Verma V, Reiter J, Metzler J, Failla A, et al. Cohesin rings devoid of Scc3 and Pds5 maintain their stable association with the DNA. PLoS Genet. 2012;8:e1002856 pubmed 出版商
Kanke M, Kodama Y, Takahashi T, Nakagawa T, Masukata H. Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components. EMBO J. 2012;31:2182-94 pubmed 出版商
Casolari J, Thompson M, Salzman J, Champion L, Moerner W, Brown P. Widespread mRNA association with cytoskeletal motor proteins and identification and dynamics of myosin-associated mRNAs in S. cerevisiae. PLoS ONE. 2012;7:e31912 pubmed 出版商
Li M, Shandilya S, Carpenter M, Rathore A, Brown W, Perkins A, et al. First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G. ACS Chem Biol. 2012;7:506-17 pubmed 出版商
Sarkar T, Sharan S, Wang J, Pawar S, Cantwell C, Johnson P, et al. Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells. Mol Cell Biol. 2012;32:320-32 pubmed 出版商
Fukuura M, Nagao K, Obuse C, Takahashi T, Nakagawa T, Masukata H. CDK promotes interactions of Sld3 and Drc1 with Cut5 for initiation of DNA replication in fission yeast. Mol Biol Cell. 2011;22:2620-33 pubmed 出版商
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Demorest Z, MacDuff D, Brown W, Morham S, Parise L, Harris R. The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination. PLoS ONE. 2010;5:e11660 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
c Myc单克隆抗体(9E11)
目录# :
MA1-16637
规格 :
100微升
价格 :
美国450.00
克隆性 :
单克隆
纯度 :
蛋白质A/G
宿主 :
小鼠
反应物种 :
鸡, 人类, 小鼠, 大鼠, 酵母
应用 :
ChIP Assay: 2 µg/500 µg extract, ELISA: 1:100-1:2,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: 2 µg/mg lysate, Western Blot: 1:500-1:1,000
物种 :
鸡, 人类, 小鼠, 大鼠, 酵母
克隆 :
9E11
抗体亚型 :
IgG2a, kappa
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
The c-Myc protein is a 62 kDa transcription factor that is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies have shown that c-Myc is essential for vasculogenesis and angiogenesis in tumor development, which distributes blood throughout the cells. The c-myc oncogene (p62 c-myc) is involved in the control of normal cellular proliferation and differentiation, and the deregulated expression of c-Myc induces apoptosis in different cell types. Antibodies against c-myc epitopes recognize overexpressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins. c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (delta light chain); or 22 (light chain) is described in Burkitts lymphoma and other B-cell lymphoproliferative conditions. An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.
免疫原 :
Synthetic peptide, conjugated to KLH, corresponding to residues A(408) E E Q K L I S E E D L(420) of human c-Myc.
格式 :
液体
应用w/稀释 :
ChIP Assay: 2 µg/500 µg extract, ELISA: 1:100-1:2,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: 2 µg/mg lysate, Western Blot: 1:500-1:1,000
别名 :
AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; class E basic helix-loop-helix protein 39; cmyc; c-Myc; c-myc epitope tag; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; MYC proto-oncogene, bHLH transcription factor; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene-like protein
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国