产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3单克隆抗体(CPP32 4-1-18)
目录 :
MA1-16843
规格 :
200µL
价格 :
425.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CPP32 4-1-18
反应物种 :
bees , 人类, 小鼠, 大鼠, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 10
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠; 1:500; 图 4a
Fodor R, Georgescu A, Grigorescu B, Cioc A, Veres M, Cotoi O, et al. Caspase 3 expression and plasma level of Fas ligand as apoptosis biomarkers in inflammatory endotoxemic lung injury. Rom J Morphol Embryol. 2016;57:951-957 pubmed
  • 免疫组化-石蜡切片; 大鼠; 1:500; 图 3g
Nooh H, Nour Eldien N. The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis. Acta Histochem. 2016;118:588-595 pubmed 出版商
  • 免疫印迹; 人类; 1:250; 图 2
Soto Nuñez M, Díaz Morales K, Cuautle Rodríguez P, Torres Flores V, Lopez Gonzalez J, Mandoki Weitzner J, et al. Single-cell microinjection assay indicates that 7-hydroxycoumarin induces rapid activation of caspase-3 in A549 cancer cells. Exp Ther Med. 2015;10:1789-1795 pubmed
  • 免疫组化-石蜡切片; bees
Higes M, Juarranz A, Dias Almeida J, Lucena S, Botías C, Meana A, et al. Apoptosis in the pathogenesis of Nosema ceranae (Microsporidia: Nosematidae) in honey bees (Apis mellifera). Environ Microbiol Rep. 2013;5:530-6 pubmed 出版商
  • 免疫组化; 小鼠; 1:50
Gezginci Oktayoglu S, Sacan O, Yanardag R, Karatug A, Bolkent S. Exendin-4 improves hepatocyte injury by decreasing proliferation through blocking NGF/TrkA in diabetic mice. Peptides. 2011;32:223-31 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Tunçdemir M, Demirkesen O, Ozturk M, Atukeren P, Gumustas M, Turan T. Antiapoptotic effect of angiotensin-II type-1 receptor blockade in renal tubular cells of hyperoxaluric rats. Urol Res. 2010;38:71-80 pubmed 出版商
  • 免疫组化; domestic rabbit; 1:100
Mor F, Ozmen O. Effect of vitamin C in reducing the toxicity of endosulfan in liver in rabbits. Exp Toxicol Pathol. 2010;62:75-80 pubmed 出版商
  • 免疫组化; 人类
Chu P, Jung S, Yeh C, Wu H, Shiu T, She H, et al. Expression of caspase-3-dependent apoptosis in mural thrombi leukocytes. APMIS. 2008;116:995-9 pubmed 出版商
  • 免疫印迹; 小鼠; 1:50
Gezginci Oktayoglu S, Tunali S, Yanardag R, Bolkent S. Effects of Z-FA.FMK on D-galactosamine/tumor necrosis factor-alpha-induced kidney injury and oxidative stress in mice : effects of Z-FA.FMK on TNF-alpha-mediated kidney injury. Mol Cell Biochem. 2008;309:9-20 pubmed
  • 免疫组化; 大鼠; 图 5
Damron T, Horton J, Naqvi A, Margulies B, Strauss J, Grant W, et al. Decreased proliferation precedes growth factor changes after physeal irradiation. Clin Orthop Relat Res. 2004;:233-42 pubmed
图像
图像 1 :
赛默飞世尔 MA1-16843 图像 1
Western blot detection of Caspase (19 and 35 kDa) from HEK293 cell extract using MA1-16843. Lanes 1 and 2 contain inactive and active Caspase, respectively.
产品信息
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3单克隆抗体(CPP32 4-1-18)
目录# :
MA1-16843
规格 :
200µL
价格(美元) :
425.00美元
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunohistochemistry (Paraffin): 1:200-1:500, Western Blot: 1:500-1:1000
物种 :
人类, 小鼠, 大鼠
克隆 :
CPP32 4-1-18
抗体亚型 :
IgG2a, kappa
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
免疫原 :
全长重组人类胱氨酸-天冬氨酸蛋白酶3蛋白
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:200-1:500, Western Blot: 1:500-1:1000
别名 :
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; Protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国