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抗体

CD7单克隆抗体(最小必需培养基-186)

MA1-19080

100微克

美国322.00

单克隆

小鼠

未共轭

最小必需培养基-186

免疫印迹, 免疫组化, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片

CD7单克隆抗体(最小必需培养基-186)

MA1-19080

100微克

美国322.00

单克隆

蛋白质A

小鼠

人类

Flow Cytometry: 2 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

人类

最小必需培养基-186

IgG1

4° C, 不冻结

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.

Human acute myelogenous leukaemia cell line KG-1.

液体

Flow Cytometry: 2 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41