产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD14单克隆抗体(B-A8)
目录 :
MA1-19240
规格 :
100微克
价格 :
美国366
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B-A8
反应物种 :
人类
应用 :
酶联免疫吸附测定, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 6
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Paupert J, Mansat De Mas V, Demur C, Salles B, Muller C. Cell-surface MMP-9 regulates the invasive capacity of leukemia blast cells with monocytic features. Cell Cycle. 2008;7:1047-53 pubmed
|
| Semnani R, Sabzevari H, Iyer R, Nutman T. Filarial antigens impair the function of human dendritic cells during differentiation. Infect Immun. 2001;69:5813-22 pubmed
|
| Matasic R, Dietz A, Vuk Pavlovic S. Maturation of human dendritic cells as sulfasalazine target. Croat Med J. 2001;42:440-5 pubmed
|
| Matasic R, Dietz A, Vuk Pavlovic S. Cyclooxygenase-independent inhibition of dendritic cell maturation by aspirin. Immunology. 2000;101:53-60 pubmed
|
| McRae B, Nagai T, Semnani R, van Seventer J, van Seventer G. Interferon-alpha and -beta inhibit the in vitro differentiation of immunocompetent human dendritic cells from CD14(+) precursors. Blood. 2000;96:210-7 pubmed
|
Harvey H, Post D, Apicella M. Immortalization of human urethral epithelial cells: a model for the study of the pathogenesis of and the inflammatory cytokine response to Neisseria gonorrhoeae infection. Infect Immun. 2002;70:5808-15 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD14单克隆抗体(B-A8)
目录# :
MA1-19240
规格 :
100微克
价格 :
美国366
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: Assay Dependent, Flow Cytometry: Assay Dependent, Immunohistochemistry (Paraffin): 2-10 µg/mL
物种 :
人类
克隆 :
B-A8
抗体亚型 :
IgG1
储存 :
4° C, 不冻结
描述 :
CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.
免疫原 :
人类单核细胞
格式 :
液体
应用w/稀释 :
ELISA: Assay Dependent, Flow Cytometry: Assay Dependent, Immunohistochemistry (Paraffin): 2-10 µg/mL
别名 :
CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; Monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; Myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14
更多信息或购买 :
公司信息
赛默飞世尔