产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD38单克隆抗体(HIT2)
目录 :
MA1-19316
规格 :
100微克
价格 :
美国410
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
HIT2
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 29
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| Keefer M, Zheng B, Rosenberg A, Kobie J. Increased Steady-State Memory B Cell Subsets Among High-Risk Participants in an HIV Vaccine Trial. AIDS Res Hum Retroviruses. 2016;32:1143-1148 pubmed
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| Diaz Blanco E, Bruns I, Neumann F, Fischer J, Graef T, Rosskopf M, et al. Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase. Leukemia. 2007;21:494-504 pubmed
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| Kolar G, Mehta D, Pelayo R, Capra J. A novel human B cell subpopulation representing the initial germinal center population to express AID. Blood. 2007;109:2545-52 pubmed
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| Kolar G, Mehta D, Wilson P, Capra J. Diversity of the Ig repertoire is maintained with age in spite of reduced germinal centre cells in human tonsil lymphoid tissue. Scand J Immunol. 2006;64:314-24 pubmed
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| Biedermann B, Gil D, Bowen D, Crocker P. Analysis of the CD33-related siglec family reveals that Siglec-9 is an endocytic receptor expressed on subsets of acute myeloid leukemia cells and absent from normal hematopoietic progenitors. Leuk Res. 2007;31:211-20 pubmed
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| Jamieson C, Gotlib J, Durocher J, Chao M, Mariappan M, Lay M, et al. The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci U S A. 2006;103:6224-9 pubmed
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| Timeus F, Crescenzio N, Sanavio F, Fazio L, Doria A, Foglia L, et al. Multilineage engraftment of refrozen cord blood hematopoietic progenitors in NOD/SCID mice. Haematologica. 2006;91:369-72 pubmed
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| Ninos J, Jefferies L, Cogle C, Kerr W. The thrombopoietin receptor, c-Mpl, is a selective surface marker for human hematopoietic stem cells. J Transl Med. 2006;4:9 pubmed
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| Crough T, Burrows J, Fazou C, Walker S, Davenport M, Khanna R. Contemporaneous fluctuations in T cell responses to persistent herpes virus infections. Eur J Immunol. 2005;35:139-49 pubmed
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| Ku C, Padilla J, Grose C, Butcher E, Arvin A. Tropism of varicella-zoster virus for human tonsillar CD4(+) T lymphocytes that express activation, memory, and skin homing markers. J Virol. 2002;76:11425-33 pubmed
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| Rutella S, Pierelli L, Bonanno G, Sica S, Ameglio F, Capoluongo E, et al. Role for granulocyte colony-stimulating factor in the generation of human T regulatory type 1 cells. Blood. 2002;100:2562-71 pubmed
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| Lewandowski D, Linassier C, Iochmann S, Degenne M, Domenech J, Colombat P, et al. Phosphatidylinositol 3-kinases are involved in the all-trans retinoic acid-induced upregulation of CD38 antigen on human haematopoietic cells. Br J Haematol. 2002;118:535-44 pubmed
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| Basch R, Zhang X, Dolzhanskiy A, Karpatkin S. Expression of CD41 and c-mpl does not indicate commitment to the megakaryocyte lineage during haemopoietic development. Br J Haematol. 1999;105:1044-54 pubmed
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| Luque R, Brieva J, Moreno A, Manzanal A, Escribano L, Villarrubia J, et al. Normal and clonal B lineage cells can be distinguished by their differential expression of B cell antigens and adhesion molecules in peripheral blood from multiple myeloma (MM) patients--diagnostic and clinical implications. Clin Exp Immunol. 1998;112:410-8 pubmed
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| Denning Kendall P, Nicol A, Horsley H, Donaldson C, Bradley B, Hows J. Is in vitro expansion of human cord blood cells clinically relevant?. Bone Marrow Transplant. 1998;21:225-32 pubmed
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图像
图像 1 :
产品信息
产品类型 :
抗体
产品名称 :
CD38单克隆抗体(HIT2)
目录# :
MA1-19316
规格 :
100微克
价格 :
美国410
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 2 µg/mL
物种 :
人类
克隆 :
HIT2
抗体亚型 :
IgG1
储存 :
4° C, 不冻结
描述 :
CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.
免疫原 :
Fetal human thymocytes.
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 2 µg/mL
别名 :
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10
更多信息或购买 :
公司信息
赛默飞世尔