产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SLP76单克隆抗体(SLP-76/03)
目录 :
MA1-19369
规格 :
100微克
价格 :
美国409
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SLP-76/03
反应物种 :
人类, 小鼠, pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
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图像
图像 1 :
产品信息
产品类型 :
抗体
产品名称 :
SLP76单克隆抗体(SLP-76/03)
目录# :
MA1-19369
规格 :
100微克
价格 :
美国409
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类, 小鼠, 猪
应用 :
Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1:1000
物种 :
人类, 小鼠, 猪
克隆 :
SLP-76/03
抗体亚型 :
IgG2b
储存 :
4° C, 不冻结
描述 :
SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
免疫原 :
Bacterially expressed fusion protein representing amino acids 216-434 of human SLP76 with histidine tag
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1:1000
别名 :
76 kDa tyrosine phosphoprotein; AI323664; BB161688; LCP2; lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm
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公司信息
赛默飞世尔