产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
STIM1单克隆抗体(CDN3H4)
目录 :
MA1-19451
规格 :
100微克
价格 :
美国440
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CDN3H4
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 6
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:200; 图 5cb
Tammineni E, Kraeva N, Figueroa L, Manno C, Ibarra C, Klip A, et al. Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes. elife. 2020;9: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:300; 图 6
Sun J, Lu F, He H, Shen J, Messina J, Mathew R, et al. STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion. J Cell Biol. 2014;207:535-48 pubmed 出版商
  • 免疫印迹; 小鼠
Li T, FINCH E, Graham V, Zhang Z, Ding J, Burch J, et al. STIM1-Ca(2+) signaling is required for the hypertrophic growth of skeletal muscle in mice. Mol Cell Biol. 2012;32:3009-17 pubmed 出版商
  • 免疫印迹; 人类
Li H, Ding X, Lopez J, Takeshima H, Ma J, Allen P, et al. Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes. J Biol Chem. 2010;285:39171-9 pubmed 出版商
Voros O, Panyi G, Hajdu P. Immune Synapse Residency of Orai1 Alters Ca2+ Response of T Cells. Int J Mol Sci. 2021;22: pubmed 出版商
Besprozvannaya M, Dickson E, Li H, Ginburg K, Bers D, Auwerx J, et al. GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells. elife. 2018;7: pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA1-19451 图像 1
图像 2 :
赛默飞世尔 MA1-19451 图像 2
产品信息
产品类型 :
抗体
产品名称 :
STIM1单克隆抗体(CDN3H4)
目录# :
MA1-19451
规格 :
100微克
价格 :
美国440
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: Assay Dependent, Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 1 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
CDN3H4
抗体亚型 :
IgG1
储存 :
4° C, 不冻结
描述 :
STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
免疫原 :
Synthetic peptide corresponding to the C-terminal cytoplasmic part of STIM1
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay Dependent, Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 1 µg/mL
别名 :
D11S4896E; GOK; IMD10; RGD:1306831}; SIM; Stim1; stim1 {ECO:0000312; STIM1L; STRMK; Stromal interaction molecule 1; stromal interaction molecule 1 precursor; TAM; TAM1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国