产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD63单克隆抗体(最小必需培养基-259), PE
目录 :
MA1-19650
规格 :
100试验
价格 :
美国469
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
最小必需培养基-259
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 3
参考文献
Machala M, Slav xed k J, Kov xe1 x10d O, Proch xe1 zkov xe1 J, P x11b n x10d xed kov xe1 K, Pa x159 enicov xe1 M, et al. Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes. Int J Mol Sci. 2021;22: pubmed 出版商
Görgens A, Bremer M, Ferrer Tur R, Murke F, Tertel T, Horn P, et al. Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material. J Extracell Vesicles. 2019;8:1587567 pubmed 出版商
Malla B, Aebersold D, Dal Pra A. Protocol for serum exosomal miRNAs analysis in prostate cancer patients treated with radiotherapy. J Transl Med. 2018;16:223 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD63单克隆抗体(最小必需培养基-259), PE
目录# :
MA1-19650
规格 :
100试验
价格 :
美国469
克隆性 :
单克隆
纯度 :
尺寸排阻色谱法
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 20 µL x 100 µL whole blood or 10^6 cells
物种 :
人类
克隆 :
最小必需培养基-259
抗体亚型 :
IgG1
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells. CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40. Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.
免疫原 :
T细胞株HPB-都是
格式 :
液体
应用w/稀释 :
Flow Cytometry: 20 µL x 100 µL whole blood or 10^6 cells
别名 :
C75951; CD 63; CD63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; tetraspanin-30; TSPAN30; Tspan-30
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国