产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ITGB1单克隆抗体(最小必需培养基-101A), PE
目录 :
MA1-19762
规格 :
100试验
价格 :
美国422
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
最小必需培养基-101A
反应物种 :
人类, 犬, pigs
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 4
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
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| Campioni D, Moretti S, Ferrari L, Punturieri M, Castoldi G, Lanza F. Immunophenotypic heterogeneity of bone marrow-derived mesenchymal stromal cells from patients with hematologic disorders: correlation with bone marrow microenvironment. Haematologica. 2006;91:364-8 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
ITGB1单克隆抗体(最小必需培养基-101A), PE
目录# :
MA1-19762
规格 :
100试验
价格 :
美国422
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
狗, 人类, 猪
应用 :
Flow Cytometry: Assay Dependent
物种 :
狗, 人类, 猪
克隆 :
最小必需培养基-101A
抗体亚型 :
IgG1
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. ITGB1 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins. ITGB1 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. Decreased expression of ITGB1 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug. ITGB1 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue. Further, ITGB1 also regulates tissue damage and disease symptoms related to inflammatory bowel disease. Through an ITGB1-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta. More than 8 beta subunits with numerous splice variant isoforms have been identified in mammals. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. The distribution pattern in adult tissues for integrin beta types are mutually exclusive. Beta1A is present in all tissues, except cardiac and skeletal muscle which express the beta1D variant.
免疫原 :
Raji Burkitt's lymphoma cell line.
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay Dependent
别名 :
4633401G24Rik; AA409975; AA960159; beta OL; Beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; GPIIA; integrin beta 1; integrin beta 1 (fibronectin receptor beta); Integrin beta1; Integrin beta-1; integrin beta-1 subunit; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; Itgb1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA
更多信息或购买 :
公司信息
赛默飞世尔