产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
钙粘蛋白N单克隆抗体(8C11)
目录 :
MA1-2002
规格 :
100微克
价格 :
美国459
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
8C11
反应物种 :
中国人仓鼠, 人类, 小鼠, 鸡, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 7
出版应用/物种/样本/稀释 | 参考文献 |
---|---|
| |
| |
| |
Wahl J, Kim Y, Cullen J, Johnson K, Wheelock M. N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane. J Biol Chem. 2003;278:17269-76 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
钙粘蛋白N单克隆抗体(8C11)
目录# :
MA1-2002
规格 :
100微克
价格 :
美国459
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
仓鼠, 人类, 小鼠, 兔
应用 :
Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50 - 1:200, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 5 µg, Western Blot: 1:1000
物种 :
仓鼠, 人类, 小鼠, 兔
克隆 :
8C11
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.
免疫原 :
Bacterial fusion protein corresponding to the extracellular domain of N-cadherin.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50 - 1:200, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 5 µg, Western Blot: 1:1000
别名 :
bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; cdh2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; LOC100344571; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; Neural cadherin; neural cadherin A; Neural cadherin-2; neural-cadherin; pac; Parachute; wu:fb47h04; XELAEV_18031953mg; ZNCAD
更多信息或购买 :
公司信息
赛默飞世尔