产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NF-H单克隆抗体(3G3)
目录 :
MA1-2012
规格 :
100微克
价格 :
美国420.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3G3
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 14
| 参考文献 |
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Silverstein A, Galigniana M, Chen M, Owens Grillo J, Chinkers M, Pratt W. Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin. J Biol Chem. 1997;272:16224-30 pubmed
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Dittmar K, Pratt W. Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation. J Biol Chem. 1997;272:13047-54 pubmed
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Gradin K, McGuire J, Wenger R, Kvietikova I, fhitelaw M, Toftgard R, et al. Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor. Mol Cell Biol. 1996;16:5221-31 pubmed
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Benson D, Mandell J, Shaw G, Banker G. Compartmentation of alpha-internexin and neurofilament triplet proteins in cultured hippocampal neurons. J Neurocytol. 1996;25:181-96 pubmed
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Owens Grillo J, Czar M, Hutchison K, Hoffmann K, Perdew G, Pratt W. A model of protein targeting mediated by immunophilins and other proteins that bind to hsp90 via tetratricopeptide repeat domains. J Biol Chem. 1996;271:13468-75 pubmed
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McGuire J, Coumailleau P, Whitelaw M, Gustafsson J, Poellinger L. The basic helix-loop-helix/PAS factor Sim is associated with hsp90. Implications for regulation by interaction with partner factors. J Biol Chem. 1995;270:31353-7 pubmed
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Czar M, Owens Grillo J, Dittmar K, Hutchison K, Zacharek A, Leach K, et al. Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex. J Biol Chem. 1994;269:11155-61 pubmed
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McGuire J, Whitelaw M, Pongratz I, Gustafsson J, Poellinger L. A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor. Mol Cell Biol. 1994;14:2438-46 pubmed
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Gradin K, Whitelaw M, Toftgard R, Poellinger L, Berghard A. A tyrosine kinase-dependent pathway regulates ligand-dependent activation of the dioxin receptor in human keratinocytes. J Biol Chem. 1994;269:23800-7 pubmed
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Hutchison K, Dittmar K, Pratt W. All of the factors required for assembly of the glucocorticoid receptor into a functional heterocomplex with heat shock protein 90 are preassociated in a self-sufficient protein folding structure, a "foldosome". J Biol Chem. 1994;269:27894-9 pubmed
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Hutchison K, Stancato L, Owens Grillo J, Johnson J, Krishna P, Toft D, et al. The 23-kDa acidic protein in reticulocyte lysate is the weakly bound component of the hsp foldosome that is required for assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90. J Biol Chem. 1995;270:18841-7 pubmed
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Coumailleau P, Poellinger L, Gustafsson J, Whitelaw M. Definition of a minimal domain of the dioxin receptor that is associated with Hsp90 and maintains wild type ligand binding affinity and specificity. J Biol Chem. 1995;270:25291-300 pubmed
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Fukunaga B, Probst M, Reisz Porszasz S, Hankinson O. Identification of functional domains of the aryl hydrocarbon receptor. J Biol Chem. 1995;270:29270-8 pubmed
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Perdew G, Whitelaw M. Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000. J Biol Chem. 1991;266:6708-13 pubmed
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图像
图像 1 :
产品信息
产品类型 :
抗体
产品名称 :
NF-H单克隆抗体(3G3)
目录# :
MA1-2012
规格 :
100微克
价格 :
美国420.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类, 大鼠
应用 :
Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:100-1:1,000
物种 :
人类, 大鼠
克隆 :
3G3
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
免疫原 :
Synthetic peptide corresponding to 226 amino acids of the C-terminus of neurofilament, heavy chain.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:100-1:1,000
别名 :
200 kDa neurofilament protein; CMT2CC; heavy neurofilament protein; I79_012512; intermediate filament protein; KIAA0845; LOW QUALITY PROTEIN: neurofilament heavy polypeptide; mKIAA0845; NEF3; Nefh; nefh.L; neurofilament; neurofilament 200kDa; neurofilament heavy; neurofilament heavy L homeolog; neurofilament heavy polypeptide; neurofilament heavy polypeptide-like; neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide L homeolog; neurofilament-H; NF 200 kD; NF200; Nfh; NF-H; NHC; XELAEV_18007418mg
更多信息或购买 :
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赛默飞世尔
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