产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
LAMP2单克隆抗体(H4B4)
目录 :
MA1-205
规格 :
100微克
价格 :
美国516.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
H4B4
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 3a
Fonteneau J, Brilot F, Münz C, Gannagé M. The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer. J Immunol. 2016;196:64-71 pubmed 出版商
Bérard M, Sheta R, Malvaut S, Rodriguez Aller R, Teixeira M, Idi W, et al. A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease. PLoS Biol. 2022;20:e3001578 pubmed 出版商
Tsai S, Atai N, Cacciottolo M, Nice J, Salehi A, Guo C, et al. Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity. J Biol Chem. 2021;297:101266 pubmed 出版商
Ressnerova A, Novotný F, Michalkova H, Pumera M, Adam V, Heger Z. Efficient Protein Transfection by Swarms of Chemically Powered Plasmonic Virus-Sized Nanorobots. ACS Nano. 2021;15:12899-12910 pubmed 出版商
Dykstra K, Fay H, Massey A, Yang N, Johnson M, Portwood S, et al. Inhibiting autophagy targets human leukemic stem cells and hypoxic AML blasts by disrupting mitochondrial homeostasis. Blood Adv. 2021;5:2087-2100 pubmed 出版商
Liu M, Pi H, Xi Y, Wang L, Tian L, Chen M, et al. KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity. Autophagy. 2021;17:903-924 pubmed 出版商
Guo C, Tsai S, Ai Y, Li M, Pekosz A, Cox A, et al. The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike. bioRxiv. 2020;: pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
LAMP2单克隆抗体(H4B4)
目录# :
MA1-205
规格 :
100微克
价格 :
美国516.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Human, Mouse, Non-human primate
应用 :
Flow Cytometry: 5-10 µg/mL, Immunocytochemistry: 2-10 µg/mL, Western Blot: 1:1,000
物种 :
Human, Mouse, Non-human primate
克隆 :
H4B4
抗体亚型 :
IgG2b
储存 :
-20°C
描述 :
LAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is approximately 46 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of about 100-130 kDa. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail. LAMP2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail. The LAMP protein has 3 variant forms: LAMP-2A, -2B, and 2C. LAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation. LAMP2 deficiency causes an accumulation of autophagosomes in many tissues leading to cardiomyopathy and myopathy (Danon’s disease).
免疫原 :
adherent spleen cells of human origin
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5-10 µg/mL, Immunocytochemistry: 2-10 µg/mL, Western Blot: 1:1,000
别名 :
CD107 antigen-like family member B; CD107b; EGK_20887; Igp96; Lamp II; LAMP2; LAMP-2; LAMP-2 Isoform 2A; LAMP-2 Variant A; Lamp-2a; Lamp-2b; Lamp-2c; LAMPB; LGP110; LGP-110; LGP-96; LGP-B; lysosomal associated membrane protein 2; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; Mac3; RP23-193O17.2
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国